Regulation of Eukaryotic Initiation Factor 4E Phosphorylation in the Nervous System of Aplysia californica

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation

1999 • 2,096 citations

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1994 • 1,684 citations

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1994 • 1,222 citations

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

1991 • 1,041 citations

Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin

1997 • 953 citations

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1997 • 927 citations

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27

1994 • 866 citations

Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage

1997 • 738 citations

PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation

1994 • 672 citations

The mRNA 5′ cap-binding protein eIF4E and control of cell growth

1998 • 651 citations

Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E

1999 • 635 citations

Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change

1995 • 575 citations

Presynaptic facilitation revisited: state and time dependence

1996 • 555 citations

MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia

1997 • 548 citations

The search for physiological substrates of MAP and SAP kinases in mammalian cells

1997 • 544 citations

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia

1994 • 528 citations

A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis

1999 • 510 citations

Phosphorylation of the Cap-Binding Protein Eukaryotic Translation Initiation Factor 4E by Protein Kinase Mnk1 In Vivo

1999 • 449 citations

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1996 • 394 citations

Structure of translation factor elF4E bound to m7GDP and interaction with 4E-binding protein

1997 • 365 citations

Stress-activated Protein Kinases: Activation, Regulation and Function

1997 • 327 citations

The Phosphorylation of Eukaryotic Initiation Factor eIF4E in Response to Phorbol Esters, Cell Stresses, and Cytokines Is Mediated by Distinct MAP Kinase Pathways

1998 • 302 citations

Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: increased cap affinity of the phosphorylated form.

1994 • 285 citations

Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

1995 • 268 citations

Phosphorylation of Eukaryotic Protein Synthesis Initiation Factor 4E at Ser-209

1995 • 210 citations

A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia

1995 • 209 citations

Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E

1991 • 168 citations

Serine 209, Not Serine 53, Is the Major Site of Phosphorylation in Initiation Factor eIF-4E in Serum-treated Chinese Hamster Ovary Cells

1995 • 149 citations

5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in aplysia sensory neurons

1989 • 149 citations

Intrasomatic Injection of Radioactive Precursors for Studying Transmitter Synthesis in Identified Neurons of Aplysia californica

1973 • 143 citations

Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia

1998 • 140 citations

Involvement of Stress-activated Protein Kinase and p38/RK Mitogen-activated Protein Kinase Signaling Pathways in the Enhanced Phosphorylation of Initiation Factor 4E in NIH 3T3 Cells

1997 • 127 citations

Regulation of translation and cell growth by eIF-4E

1994 • 121 citations

Regulation by insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion

1997 • 121 citations

Dynamics of Induction and Expression of Long-Term Synaptic Facilitation inAplysia

1996 • 109 citations

Sensitizing stimuli cause translocation of protein kinase C in Aplysia sensory neurons.

1990 • 102 citations

Phosphorylation of eIF-4E on Serine 209 by Protein Kinase C Is Inhibited by the Translational Repressors, 4E-binding Proteins

1996 • 98 citations

Similar Neuronal Alterations Induced by Axonal Injury And Learning in Aplysia

1991 • 91 citations

Phosphorylation of Mitogen-Activated Protein Kinase by One-Trial and Multi-Trial Classical Conditioning

1998 • 89 citations

Insulin receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents

1996 • 85 citations

Insulin‐stimulated phosphorylation of initiation factor 4E is mediated by the MAP kinase pathway

1996 • 76 citations

Biochemical Pathways by Which Serotonin Regulates Translation in the Nervous System of Aplysia

1998 • 62 citations

Signalling through either the p38 or ERK mitogen‐activated protein (MAP) kinase pathway is obligatory for phorbol ester and T cell receptor complex (TCR‐CD3)‐stimulated phosphorylation of initiation factor (eIF) 4E in Jurkat T cells

1997 • 52 citations

LK6, a short lived protein kinase in Drosophila that can associate with microtubules and centrosomes

1997 • 42 citations

Cellular stress in Xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein

1999 • 30 citations

Cloning and Characterization of Aplycalcin and Aplysia Neurocalcin, Two New Members of the Calmodulin Superfamily of Small Calcium-Binding Proteins

1996 • 27 citations

Stimulation of an Insulin Receptor Activates and Down‐Regulates the Ca²⁺‐Independent Protein Kinase C, Apl II, Through a Wortmannin‐Sensitive Signaling Pathway in Aplysia

1996 • 25 citations

Effect of mRNA Cap Structure on eIF-4E Phosphorylation and Cap Binding Analyses Using Ser209-Mutated eIF-4Es

1998 • 21 citations

Intracellular signalling pathways regulating initiation factor elF4E phosphorylation during the activation of cell growth

1997 • 21 citations

Phosphorylation of eIF4E at a Conserved Serine in Aplysia

1998 • 14 citations