Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide

On the Origin of Cancer Cells

1956 • 12,141 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Role of superoxide dismutase in cancer: a review.

1979 • 976 citations

Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme

1975 • 777 citations

Cyclic GMP Metabolism and Involvement in Biological Regulation

1977 • 629 citations

Biochemistry: The Molecular Basis of Cell Structure and Function

1970 • 606 citations

Morphological Transformation of Chinese Hamster Cells by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Testosterone

1971 • 529 citations

Guanosine 3′:5′-Cyclic Monophosphate: A Possible Intracellular Mediator of Mitogenic Influences in Lymphocytes

1972 • 381 citations

The Status of the Gene Map of the Human Chromosomes

1977 • 344 citations

Biochemistry, the molecular basis of cell structure and function

1976 • 316 citations

Cell Transformation by RNA Tumor Viruses

1977 • 298 citations

Role of cyclic nucleotides in cell growth and differentiation

1976 • 290 citations

The glycolysis and respiration of tumors

1961 • 285 citations

Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry

1979 • 276 citations

Subcellular localization of the superoxide-forming enzyme in human neutrophils.

1979 • 268 citations

Effects of Superoxide on the Erythrocyte Membrane

1978 • 267 citations

Evidence that the superoxide-generating system of human leukocytes is associated with the cell surface.

1977 • 240 citations

Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells

1979 • 239 citations

Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.

1977 • 238 citations

The positive control of cell proliferation by the interplay of calcium ions and cyclic nucleotides. A review

1976 • 219 citations

The insulin-like effect of hydrogen peroxide on pathways of lipid synthesis in rat adipocytes.

1979 • 196 citations

Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA synthesis following partial hepatectomy or hormone infusion

1972 • 160 citations

Activation of soluble guanylate cyclase from rat lung by incubation or by hydrogen peroxide.

1976 • 147 citations

Evidence that proteases are involved in superoxide production by human polymorphonuclear leukocytes and monocytes.

1980 • 146 citations

Control mechanisms in cancer

1976 • 138 citations

Superoxide dismutase and superoxide radical in Morris hepatomas.

1980 • 135 citations

Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene product

1979 • 133 citations

Regulation of the synthesis of catalase and peroxidase in Escherichia coli.

1978 • 132 citations

Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutases

1980 • 126 citations

Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts

1974 • 105 citations

Activation and inactivation of rat liver phosphofructokinase by phosphorylation—dephosphorylation

1975 • 98 citations

Regulation of superoxide dismutase synthesis in Escherichia coli: glucose effect

1977 • 97 citations

Superoxide Dismutase Activity of Normal Murine Liver, Regenerating Liver, and H6 Hepatoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 94 citations

Stimulation of glucose transport in rat adipocytes by insulin, adenosine, nicotinic acid and hydrogen peroxide. Role of adenosine 3′:5′-cyclic monophosphate

1979 • 89 citations

Properties and oxidative regulation of guanylate cyclase.

1977 • 83 citations

Role and Regulation of Glucose Metabolism in Proliferating Cells

1979 • 81 citations

Physiological function of superoxide dismutase in glucose-limited chemostat cultures of Escherichia coli

1977 • 74 citations

Adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate: concentrations in Morris hepatomas of different growth rates

1973 • 68 citations

Reactivity of Thiols with Superoxide Radicals

1976 • 67 citations

Superoxide dismutase activity in WI-38 cell cultures: effects of age, trypsinization and SV-40 transformation.

1974 • 67 citations

Enzymatic Aspects of Embryonic Differentiation

1954 • 65 citations

Cyclic Nucleotides in Disease

1976 • 65 citations

Reactivity of thiols with superoxide radicals.

1976 • 64 citations

Characterization of the avian sarcoma virus protein p60src

1978 • 63 citations

Similarities between a phosphoprotein (pp60src)-associated protein kinase of Rous sarcoma virus and a cyclic adenosine 3':5'-monophosphate-independent protein kinase that phosphorylates pyruvate kinase type M2.

1980 • 55 citations

The in vitro inhibition of catalase by a tumor factor.

1952 • 55 citations

Current status of the thiol redox model for the regulation of hexose transport by insulin

1976 • 44 citations

Ouabain-sensitive interaction between human red cell membrane and glycolytic enzyme complex in cytosol

1978 • 42 citations

Possible involvement of proteases in superoxide production by human polymorphonuclear leukocytes

1979 • 41 citations

Oxygen radicals and hydrogen peroxide in rat brain mitochondria

1974 • 40 citations

Increased Urinary Excretion of Cyclic Guanosine Monophosphate in Rats Bearing Morris Hepatoma 3924A

1975 • 40 citations

Inactivation of Pyruvate Kinase Type M2from Chicken Liver by Phosphorylation, Catalyzed by a cAMP-Independent Protein Kinase

1977 • 37 citations

Glucose homeostasis in rats bearing a transplantable sarcoma.

1980 • 34 citations

Comparative study of the cytoplasmic organelles of epithelial cell lines derived from human carcinomas and nonmalignant tissues.

1980 • 32 citations

Control of cell proliferation

1977 • 30 citations

Differential sensitivity of tumor cells to externally generated hydrogen peroxide. Role of glutathione and related enzymes.

1979 • 30 citations

Activation of liver guanylate cyclase by paraquat: possible role of superoxide anion.

1979 • 29 citations

Selenium induced glutathione peroxidase activity in mouse neuroblastoma cells

1977 • 27 citations

Effect of Cyclic Guanosine 3′,5′-Monophosphate on the Synthesis of Enzymes Sensitive to Catabolite Repression in Intact Cells of Escherichia coli

1974 • 24 citations

Metabolic control of glycolysis in normal and tumor permeabilized cells.

1978 • 24 citations

Role of cytoskeletal elements in cytochalasin E-induced superoxide production by human polymorphonuclear leukocytes

1979 • 20 citations

Antioxidants in neoplastic cells: I. Changes in the antioxidative capacity of mouse neuroblastoma cells measured by a single-phase assay

1978 • 18 citations

Similarities between pyruvate kinase from human placenta and tumours

1973 • 16 citations

The extra nuclear control of mitosis & cell function. A theory of cellular organisation

1980 • 12 citations

Expression of Virus Specific Morphological Cell Transformation Induced in E nucleated Cells

1976 • 11 citations

The effect of fetal calf serum on the biology of cultured primary glomerular cells.

1981 • 9 citations

Superoxide dismutase activity in normal mouse brain, prenatal brain, and neuroblastoma cells. Abstr.

1978 • 6 citations

Cyclic AMP-protein-DNA complex formation in mammalian cell-free systems.

1977 • 6 citations