CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

1995 • 1,560 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

1996 • 959 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Identification of human cancers deficient in antigen processing.

1993 • 625 citations

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

1993 • 593 citations

Transducers of life and death: TNF receptor superfamily and associated proteins.

1996 • 423 citations

Reversal of tumor-induced immunosuppression: a new approach to cancer therapy.

1997 • 219 citations

Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40‐ligand) and TNF‐α, but strongly enhanced by interleukin‐10

1995 • 215 citations

FLT3 Ligand Induces the Generation of Functionally Active Dendritic Cells in Mice

1997 • 193 citations

Reversal of Tumor-Induced Immunosuppression: A New Approach to Cancer Therapy

1997 • 182 citations

CD40 Ligand Induces an Antileukemia Immune Response In Vivo

1997 • 142 citations

Dendritic Cells: Biology and Clinical Applications

1999 • 139 citations

Dendritic cells presenting tumor antigen

1996 • 117 citations

Tumor's other immune targets: dendritic cells

1999 • 115 citations

FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma.

1998 • 103 citations

Getting to the Source: Dendritic Cells as Therapeutic Reagents for the Treatment of Patients With Cancer

1997 • 95 citations

FLT3-Ligand Administration Inhibits Liver Metastases: Role of NK Cells

1998 • 94 citations

IMMUNOLOGIC DYSFUNCTION IN CANCER

1996 • 78 citations

Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells.

1998 • 76 citations

Antitumor Responses Induced by Transgenic Expression of CD40 Ligand

1997 • 66 citations

CD40 inhibits B cell apoptosis by upregulating bcl-xL expression and blocking oxidant accumulation

1997 • 62 citations

The use of dendritic cells for cancer vaccination.

1999 • 58 citations

Antitumor Activities of IL-12 and Mechanisms of Action

1997 • 54 citations

Genetic modification of a carcinoma with the IL-4 gene increases the influx of dendritic cells relative to other cytokines

1997 • 45 citations

Deleted Work

1955 • 0 citations