Analysis of Clathrin-mediated Endocytosis of Epidermal Growth Factor Receptor by RNA Interference

Expression profiling reveals off-target gene regulation by RNAi

2003 • 2,294 citations

Rational siRNA design for RNA interference

2004 • 1,991 citations

Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi

2002 • 1,422 citations

Analysis of gene function in somatic mammalian cells using small interfering RNAs

2002 • 1,108 citations

Signal transduction and endocytosis: close encounters of many kinds

2002 • 820 citations

Simultaneous Binding of PtdIns(4,5)P ₂ and Clathrin by AP180 in the Nucleation of Clathrin Lattices on Membranes

2001 • 719 citations

Clathrin-mediated endocytosis in AP-2–depleted cells

2003 • 679 citations

Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles

2001 • 626 citations

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

2002 • 626 citations

Three ways to make a vesicle

2000 • 547 citations

Accessory factors in clathrin-dependent synaptic vesicle endocytosis

2000 • 513 citations

AP-2/Eps15 Interaction Is Required for Receptor-mediated Endocytosis

1998 • 345 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Clathrin Assembly Lymphoid Myeloid Leukemia (CALM) Protein: Localization in Endocytic-coated Pits, Interactions with Clathrin, and the Impact of Overexpression on Clathrin-mediated Traffic

1999 • 317 citations

Grb2 Regulates Internalization of EGF Receptors through Clathrin-coated Pits

2003 • 306 citations

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

2002 • 305 citations

A Structural Explanation for the Binding of Multiple Ligands by the α-Adaptin Appendage Domain

1999 • 284 citations

Effect of Clathrin Heavy Chain- and α-Adaptin-specific Small Inhibitory RNAs on Endocytic Accessory Proteins and Receptor Trafficking in HeLa Cells

2003 • 261 citations

Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system.

1988 • 236 citations

Epidermal Growth Factor and Membrane Trafficking

2000 • 233 citations

Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization.

1990 • 207 citations

eps15 and eps15R are essential components of the endocytic pathway.

1997 • 201 citations

Differential requirements for AP-2 in clathrin-mediated endocytosis

2003 • 194 citations

Epidermal Growth Factor Receptor Internalization through Clathrin-Coated Pits Requires Cbl RING Finger and Proline-Rich Domains But Not Receptor Polyubiquitylation

2003 • 139 citations

Preparation and Analysis of the Common Urinary Forms of Human Chorionic Gonadotropin

2000 • 131 citations

Stoichiometric Interaction of the Epidermal Growth Factor Receptor with the Clathrin-associated Protein Complex AP-2

1995 • 119 citations

[24] Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

1995 • 109 citations

Endocytosis of the Viral Chemokine Receptor US28 Does Not Require Beta‐Arrestins But Is Dependent on the Clathrin‐Mediated Pathway

2003 • 108 citations

The Eps15 homology (EH) domain

2001 • 90 citations

Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis

2003 • 80 citations

Eps15R Is a Tyrosine Kinase Substrate with Characteristics of a Docking Protein Possibly Involved in Coated Pits-mediated Internalization

1998 • 78 citations

[1] Advanced 5′-silyl-2′-orthoester approach to RNA oligonucleotide synthesis

2000 • 59 citations