Nerve growth factor abrogates the tumorigenicity of human small cell lung cancer cell lines

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1994 • 1,065 citations

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

1994 • 978 citations

The neurotrophic factor concept: a reexamination

1993 • 745 citations

Association between High Levels of Expression of the TRK Gene and Favorable Outcome in Human Neuroblastoma

1993 • 698 citations

Nerve growth factor: from neurotrophin to neurokine

1996 • 687 citations

Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene

1990 • 606 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

A simple, rapid method for the purification of poly A+ RNA.

1988 • 382 citations

Treatment and Prevention of Rat Glioblastoma by Immunogenic C6 Cells Expressing Antisense Insulin-Like Growth Factor I RNA

1993 • 328 citations

Paraneoplastic myasthenic syndrome IgG inhibits 45Ca2+ flux in a human small cell carcinoma line

1985 • 248 citations

Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

1997 • 229 citations

Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis.

1993 • 208 citations

Expression of neuroendocrine cell markers L-dopa decarboxylase, chromogranin A, and dense core granules in human tumors of endocrine and nonendocrine origin.

1988 • 184 citations

The p53 tumor suppressor protein, a modulator of cell proliferation.

1992 • 171 citations

Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity.

1995 • 152 citations

Co‐expression of urokinase, urokinase receptor and PAI‐1 is necessary for optimum invasiveness of cultured lung cancer cells

1995 • 146 citations

Growth of human small cell (oat cell) carcinoma of the lung in serum-free growth factor-supplemented medium.

1980 • 134 citations

Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma

1994 • 133 citations

Mediation of NGF-stimulated extracellular matrix invasion by the human melanoma low-affinity p75 neurotrophin receptor: melanoma p75 functions independently of trkA.

1993 • 122 citations

Effects of phorbol ester tumor promoters and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells.

1982 • 118 citations

Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line.

1993 • 106 citations

Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines.

1992 • 106 citations

Nerve growth factor suppresses the transforming phenotype of human prolactinomas.

1993 • 92 citations

Serotonin release and cell proliferation are under the control of α‐bungarotoxin‐sensitive nicotinic receptors in small‐cell lung carcinoma cell lines

1994 • 86 citations

Association of neurotrophin receptor expression and differentiation in human neuroblastoma.

1995 • 83 citations

Calcium channel subtypes controlling serotonin release from human small cell lung carcinoma cell lines.

1993 • 83 citations

Nerve growth factor stimulates clonal growth of human lung cancer cell lines and a human glioblastoma cell line expressing high-affinity nerve growth factor binding sites involving tyrosine kinase signaling.

1995 • 75 citations

Nerve growth factor in the anterior pituitary: localization in mammotroph cells and cosecretion with prolactin by a dopamine-regulated mechanism.

1996 • 69 citations

Heterogeneity of human neuroblastoma cell lines in their proliferative responses to basic FGF, NGF, and EGF: Correlation with expression of growth factors and growth factor receptors

1995 • 61 citations

Neuronal‐type nicotinic receptors in human neuroblastoma and small‐cell lung carcinoma cell lines

1992 • 60 citations

Nerve growth factor controls proliferation and progression of human prolactinoma cell lines through an autocrine mechanism.

1996 • 59 citations

p75(NGFR) and TrkA receptors collaborate to rapidly activate a p75(NGFR)-associated protein kinase.

1996 • 53 citations

Nerve growth factor receptors in chromatin of melanoma cells, proliferating melanocytes, and colorectal carcinoma cells in vitro.

1988 • 51 citations

Voltage-operated calcium channels in small cell lung carcinoma cell lines: pharmacological, functional, and immunological properties.

1990 • 49 citations

Nerve Growth and Expression of Receptors for Nerve Growth Factor in Tumors of Melanocyte Origin

1991 • 49 citations

Biology of small-cell lung cancer

1992 • 48 citations

Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype.

1994 • 48 citations

Steady-state polypeptide modulations associated with nerve growth factor (NGF)-induced terminal differentiation and NGF deprivation-induced apoptosis in human neuroblastoma cells.

1992 • 41 citations

Nerve growth factor receptor expression in peripheral and central neuroectodermal tumors, other pediatric brain tumors, and during development of the adrenal gland.

1991 • 39 citations

Inhibition of tumor growth in liver epithelial cells transfected with a transforming growth factor alpha antisense gene.

1994 • 35 citations

Mitogenic effect of neurotrophic factors on human imr 32 neuroblastoma cells

1990 • 28 citations

Nerve growth factor may stimulate either division or differentiation of cloned C1300 neuroblastoma cells in serum‐free cultures

1980 • 28 citations

Human central nervous system primitive neuroectodermal tumor expressing nerve growth factor receptors: CHP707M

1990 • 27 citations

Antagonistic effect of PDGF and NGF on transcription of ribosomal DNA and tumor cell proliferation

1989 • 24 citations

Nerve growth factor and bromocriptine: a sequential therapy for human bromocriptine-resistant prolactinomas

1995 • 24 citations

Chromatin and cell surface receptors mediate melanoma cell growth response to nerve growth factor

1991 • 11 citations

Immunolocalization of secretogranin II and insulin in a nerve growth factor-differentiated insulinoma cell line.

1995 • 7 citations