Direct activation of dendritic cells by the malaria parasite,Plasmodium chabaudi chabaudi

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

1999 • 2,950 citations

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

1995 • 1,560 citations

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

2000 • 1,175 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

CD8α+ and CD8α− Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

1999 • 998 citations

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

1997 • 937 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria

1990 • 861 citations

Dendritic Cell Survival and Maturation Are Regulated by Different Signaling Pathways

1998 • 685 citations

Interleukin‐12 is produced by dendritic cells and mediates T helper 1 development as well as interferon‐γ production by T helper 1 cells

1996 • 676 citations

Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells

1999 • 633 citations

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

1997 • 455 citations

Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

2001 • 376 citations

Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control.

1992 • 342 citations

IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism.

1995 • 314 citations

Dendritic cells, but not macrophages, produce IL-12 immediately followingLeishmania donovani infection

1998 • 271 citations

Tumor‐Necrosis Factor and other Cytokines in Cerebral Malaria: Experimental and Clinical Data

1989 • 264 citations

TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation

1999 • 262 citations

A Defect in Interleukin-10 Leads to Enhanced Malarial Disease inPlasmodium chabaudi chabaudiInfection in Mice

1999 • 232 citations

Coordinated events during bacteria-induced DC maturation

1999 • 219 citations

Frequencies of CD4⁺ T cells reactive with Plasmodium chabaudi chabaudi: distinct response kinetics for cells with T_h1 and T_h2 characteristics during infection

1989 • 185 citations

Early gamma interferon responses in lethal and nonlethal murine blood-stage malaria

1997 • 179 citations

Critical role of NK1+ T cells in IL-12-induced immune responses in vivo.

1998 • 179 citations

Cutting Edge: Critical Role of NK1+ T Cells in IL-12-Induced Immune Responses In Vivo

1998 • 136 citations

Mycobacterium tuberculosis‐activated dendritic cells induce protective immunityin mice

2000 • 129 citations

A Th1-associated increase in tumor necrosis factor alpha expression in the spleen correlates with resistance to blood-stage malaria in mice

1996 • 117 citations

Salmonella efficiently enter and survive within cultured CD11c+ dendritic cells initiating cytokine expression

1999 • 113 citations

Neutralizing monoclonal antibodies to glycosylphosphatidylinositol, the dominant TNF-α-inducing toxin ofPlasmodium falciparum: prospects for the immunotherapy of severe malaria

1993 • 108 citations

Role of gamma interferon during infection with Plasmodium chabaudi chabaudi

1990 • 102 citations

Plasmodium chabaudi -Infected Erythrocytes Adhere to CD36 and Bind to Microvascular Endothelial Cells in an Organ-Specific Way

2000 • 86 citations

The Response of CD4⁺ T Cells to Plasmodium chabaudi chabaudi

1989 • 81 citations

Preformed Membrane-Associated Stores of Interleukin (Il)-12 Are a Previously Unrecognized Source of Bioactive IL-12 That Is Mobilized within Minutes of Contact with an Intracellular Parasite

2000 • 73 citations

Functional recognition of in vivo processed self antigen

1994 • 53 citations

Interleukin-12 corrects severe anemia during blood-stage Plasmodium chabaudi AS in susceptible A/J mice.

1998 • 47 citations

Isolation and characterization of parasites and host cell ghosts from erythrocytes infected with Plasmodium chabaudi

1987 • 40 citations

Modulation of CD11C⁺ splenic dendritic cell functions in murine visceral leishmaniasis: correlation with parasite replication in the spleen

2000 • 30 citations

New derivative of pMUS for quantitation of mouse IL-12 (p35, p40), IL-10 and IFN-gamma-R mRNAs.

1994 • 10 citations