Serotonin-Induced Regulation of the Actin Network for Learning-Related Synaptic Growth Requires Cdc42, N-WASP, and PAK in Aplysia Sensory Neurons

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho GTPases in cell biology

2002 • 4,662 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses

2001 • 3,785 citations

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

1998 • 2,538 citations

Dendritic spine changes associated with hippocampal long-term synaptic plasticity

1999 • 1,694 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite

1999 • 964 citations

Structural Changes Accompanying Memory Storage

1993 • 851 citations

Quantitative Fluorescence Resonance Energy Transfer Measurements Using Fluorescence Microscopy

1998 • 841 citations

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

Actin-Based Plasticity in Dendritic Spines

2000 • 813 citations

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia

1986 • 767 citations

Small GTPases Rac and Rho in the Maintenance of Dendritic Spines and Branches in Hippocampal Pyramidal Neurons

2000 • 710 citations

Hippocampal LTP Is Accompanied by Enhanced F-Actin Content within the Dendritic Spine that Is Essential for Late LTP Maintenance In Vivo

2003 • 685 citations

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

1996 • 667 citations

Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase

1998 • 667 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

1997 • 601 citations

Activation of Rac and Cdc42 Video Imaged by Fluorescent Resonance Energy Transfer-Based Single-Molecule Probes in the Membrane of Living Cells

2002 • 558 citations

EphA Receptors Regulate Growth Cone Dynamics through the Novel Guanine Nucleotide Exchange Factor Ephexin

2001 • 537 citations

The Role of Local Actin Instability in Axon Formation

1999 • 526 citations

A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis

1999 • 510 citations

Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin- Mediated Cell-Cell Adhesion

1998 • 505 citations

Regulation of Dendritic Growth and Remodeling by Rho, Rac, and Cdc42

1997 • 493 citations

A novel ras-related gene family

1985 • 487 citations

Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines

1996 • 454 citations

Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases

2002 • 444 citations

Morphological Basis of Long-Term Habituation and Sensitization in Aplysia

1983 • 420 citations

PAK to the future

1999 • 391 citations

Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain

1996 • 378 citations

Dynamic actin filaments are required for stable long-term potentiation (LTP) in area CA1 of the hippocampus

2000 • 367 citations

Actin has a molecular scaffolding, not propulsive, role in presynaptic function

2003 • 321 citations

C<scp>ELL</scp>-C<scp>ELL</scp> S<scp>IGNALING</scp> D<scp>URING</scp> S<scp>YNAPSE</scp> F<scp>ORMATION IN THE</scp> CNS

2003 • 306 citations

Signalling and crosstalk of Rho GTPases in mediating axon guidance

2002 • 299 citations

A Role for P21-Activated Kinase in Endothelial Cell Migration

1999 • 295 citations

Long-term memory in Aplysia modulates the total number of varicosities of single identified sensory neurons.

1988 • 291 citations

Remodeling of Synaptic Actin Induced by Photoconductive Stimulation

2001 • 275 citations

The Persistence of Long-Term Memory

2004 • 274 citations

Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice

2004 • 272 citations

Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration

2000 • 245 citations

p21-activated Kinase (PAK1) Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Kinase-1 (PDK1)

2000 • 235 citations

Target-Dependent Structural Changes Accompanying Long-Term Synaptic Facilitation in Aplysia Neurons

1990 • 230 citations

Filopodia, Spines, and the Generation of Synaptic Diversity

2000 • 183 citations

Inhibitors of protein and RNA synthesis block structural changes that accompany long-term heterosynaptic plasticity in Aplysia

1992 • 181 citations

Synaptic plasticity in vitro: cell culture of identified Aplysia neurons mediating short-term habituation and sensitization

1986 • 174 citations

Rho proteins: Targets for bacterial toxins

1997 • 172 citations

Rapid Increase in Clusters of Presynaptic Proteins at Onset of Long-Lasting Potentiation

2001 • 168 citations

Presynaptic Activation of Silent Synapses and Growth of New Synapses Contribute to Intermediate and Long-Term Facilitation in Aplysia

2003 • 139 citations

Long-term sensitization in Aplysia increases the number of presynaptic contacts onto the identified gill motor neuron L7.

1988 • 120 citations

Stimulation of phospholipase C-β₂by the Rho GTPases Cdc42Hs and Rac1

1998 • 117 citations

Presynaptic Morphological Changes Associated with Long-Term Synaptic Facilitation Are Triggered by Actin Polymerization at Preexisting Varicositis

2000 • 84 citations

Parameters influencing ectopic gene expression in Aplysia neurons

1996 • 63 citations