Effect of recombinant human nerve growth factor on presynaptic cholinergic function in rat hippocampal slices following partial septohippocampal lesions: Measures of [3H]acetylcholine synthesis, [3H]acetylcholine release and choline acetyltransferase activity

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem

1986 • 4,155 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1986 • 1,458 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease

1983 • 811 citations

An immunohistochemical study of the nerve growth factor receptor in developing rats

1988 • 610 citations

Cholinergic function and intellectual decline in Alzheimer's disease

1986 • 605 citations

The physiological function of nerve growth factor in the central nervous system: Comparison with the periphery

1987 • 558 citations

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system.

1986 • 525 citations

The expression, localization and functional significance of β-nerve growth factor in the central nervous system

1987 • 496 citations

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

1989 • 470 citations

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

1984 • 446 citations

Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra

1979 • 422 citations

Expression of the β-Nerve Growth Factor Gene in Hippocampal Neurons

1988 • 356 citations

Differential Alteration of Various Cholinergic Markers in Cortical and Subcortical Regions of Human Brain in Alzheimer's Disease

1988 • 334 citations

Morphological response of axotomized septal neurons to nerve growth factor

1988 • 323 citations

Rat β‐nerve growth factor sequence and site of synthesis in the adult hippocampus

1988 • 309 citations

Survival of Adult Basal Forebrain Cholinergic Neurons After Loss of Target Neurons

1990 • 282 citations

Exocytosis

1990 • 260 citations

Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: Response to fimbria‐fornix transection

1989 • 255 citations

NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat

1989 • 243 citations

Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: Colocalization with cholinergic neurons

1989 • 239 citations

Delayed treatment with nerve growth factor reverses the apparent loss of cholinergic neurons after acute brain damage

1988 • 233 citations

Rescue of lesioned septal cholinergic neurons by nerve growth factor: specificity and requirement for chronic treatment

1988 • 213 citations

Choline acetyltransferase immunohistochemistry in brains of alzheimer's disease patients and controls

1983 • 206 citations

Nerve growth factor receptor is associated with cholinergic neurons of the basal forebrain but not the pontomesencephalon

1989 • 206 citations

Nerve growth factor (NGF) reverses axotomy-induced decreases in choline acetyltransferase, NGF receptor and size of medial septum cholinergic neurons

1989 • 197 citations

GLUCOSE METABOLISM AND ACETYLCHOLINE SYNTHESIS IN RELATION TO NEURONAL ACTIVITY IN ALZHEIMER'S DISEASE

1980 • 196 citations

Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease

1983 • 194 citations

Behavioural and neurochemical effects of chronic intraventricular injections of nerve growth factor in adult rats with fimbria lesions

1985 • 172 citations

Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease

1989 • 168 citations

Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury

1988 • 153 citations

Experimental approaches to age-related cognitive impairments

1988 • 149 citations

Transient expression of NGF-receptor-like immunoreactivity in postnatal rat brain and spinal cord

1988 • 134 citations

Increased beta-nerve growth factor messenger RNA and protein levels in neonatal rat hippocampus following specific cholinergic lesions

1987 • 132 citations

Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients

1989 • 118 citations

Spatial learning in rats: Correlation with cortical choline acetyltransferase and improvement with NGF following NBM damage

1989 • 117 citations

Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection

1990 • 113 citations

Nerve growth factor mRNA in brain: Localization by in situ hybridization

1986 • 110 citations

Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat

1991 • 106 citations

Coexistence of choline acetyltransferase and nerve growth factor receptors in the rat basal forebrain

1988 • 102 citations

Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy.

1990 • 97 citations

Exogenous Nerve Growth Factor Increases the Activity of High‐Affinity Choline Uptake and Choline Acetyltransferase in Brain of Fisher 344 Male Rats

1990 • 95 citations

Nerve Growth Factor: Enhanced Recovery of Feeding after Hypothalamic Damage

1973 • 93 citations

Secretory Vesicle-Associated Proteins and Their Role in Exocytosis

1990 • 90 citations

Nerve growth factor affects uninjured, adult rat septohippocampal cholinergic neurons

1989 • 87 citations

Effects of nerve growth factor on behavioral recovery following caudate nucleus lesions in rats

1978 • 77 citations

Long-term effects of nerve growth factor and neural transplants on behavior of rats with medial septal lesions

1986 • 76 citations

Interaction between nerve growth factor and GM1 monosialoganglioside in preventing cortical choline acetyltransferase and high affinity choline uptake decrease after lesion of the nucleus basalis

1989 • 75 citations

Axotomy-dependent stimulation of choline acetyltransferase activity by exogenous mouse nerve growth factor in adult rat basal forebrain

1989 • 67 citations

Long-term administration of mouse nerve growth factor to adult rats with partial lesions of the cholinergic septohippocampal pathway

1990 • 66 citations

Chapter 7 The current status of the cortical cholinergic system in Alzheimer's disease and Parkinson's disease

1986 • 57 citations

Distribution of β‐nerve growth factor receptors in the human basal forebrain

1989 • 48 citations

Potential Neurotrophic Factors in the Mammalian Central Nervous System: Functional Significance in the Developing and Aging Brain

1990 • 48 citations

Nerve Growth Factor Increases the Intracellular Content of Acetylcholine in Cultured Septal Neurons from Developing Rats

1988 • 47 citations

Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice cultures

1990 • 43 citations

Nerve growth factor produces a temporary facilitation of recovery from entorhinal cortex lesions

1983 • 38 citations

Vasoactive Intestinal Peptide Increases Acetylcholine Synthesis by Rat Hippocampal Slices

1988 • 37 citations

Neurotrophic factors and Alzheimer's disease

1989 • 27 citations

Neonatal brain damage and recovery: Intraventricular injection of NGF at time of injury alters performance of active avoidance

1985 • 23 citations

Nerve Growth Factor and Behavioral Recovery After Brain Damage in Rats

1991 • 10 citations

Nerve Growth Factor

1988 • 10 citations

Nuclear Testing Violations: Keeping It All in the Family

1974 • 4 citations