Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease

Cholinergic innervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (Substantia innominata), and hypothalamus in the rhesus monkey

1983 • 1,898 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1986 • 1,458 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

1987 • 1,031 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation.

1985 • 941 citations

The organization and some projections of cholinergic neurons of the mammalian forebrain

1982 • 821 citations

Alzheimer's Disease

1986 • 772 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?

1983 • 725 citations

Cholinergic function and intellectual decline in Alzheimer's disease

1986 • 605 citations

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat

1984 • 598 citations

Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry

1984 • 586 citations

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system.

1986 • 525 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

Dorsal Root Ganglion Neurons Are Destroyed by Exposure in Utero to Maternal Antibody to Nerve Growth Factor

1980 • 500 citations

Nerve growth factor increases choline acetyl-transferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons

1985 • 491 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Choline Acetyltransferase Activity in Striatum of Neonatal Rats Increased by Nerve Growth Factor

1985 • 483 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system

1983 • 461 citations

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

1984 • 446 citations

Nerve Growth Factor Gene Expression in the Developing Rat Brain

1986 • 436 citations

Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra

1979 • 422 citations

Acetylcholinesterase-rich projections from the basal forebrain of the rhesus monkey to neocortex

1976 • 417 citations

Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in alzheimer's disease

1985 • 407 citations

Distribution of neuronal receptors for nerve growth factor in the rat

1986 • 398 citations

Nerve growth factor and Alzheimer's disease

1986 • 378 citations

Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons

1986 • 377 citations

Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum

1983 • 359 citations

Expression of the β-Nerve Growth Factor Gene in Hippocampal Neurons

1988 • 356 citations

Neurochemical Studies of Early-Onset Alzheimer's Disease

1985 • 356 citations

New Perspectives on Alzheimer's Disease

1986 • 349 citations

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

1986 • 335 citations

Identification of central cholinergic neurons containing both choline acetyltransferase and acetylcholinesterase and of central neurons containing only acetylcholinesterase

1983 • 335 citations

The Biology and Mechanism of Action of Nerve Growth Factor

1982 • 324 citations

Development of septal cholinergic neurons in culture: plating density and glial cells modulate effects of NGF on survival, fiber growth, and expression of transmitter-specific enzymes

1988 • 321 citations

Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies.

1984 • 318 citations

Nerve growth factor (NGF) stimulation of cholinergic telencephalic neurons in aggregating cell cultures

1982 • 291 citations

Localization of nerve growth factor receptors in cholinergic neurons of the human basal forebrain

1986 • 289 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase

1984 • 285 citations

Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system

1987 • 268 citations

Nerve growth factor receptor molecules in rat brain.

1986 • 268 citations

MOLECULAR BIOLOGY OF ALZHEIMER'S DISEASE

1989 • 266 citations

The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia

1984 • 265 citations

Expression of NGF receptor in the developing and adult primate central nervous system

1988 • 251 citations

Nerve growth factor promotes cholinergic development in brain striatal cultures.

1985 • 245 citations

Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brain

1987 • 237 citations

Neurotrophic Factors

1985 • 230 citations

Rescue of lesioned septal cholinergic neurons by nerve growth factor: specificity and requirement for chronic treatment

1988 • 213 citations

Topography of the Magnocellular Basal Forebrain System in Human Brain

1984 • 194 citations

Basal forebrain magnocellular neurons stain for nerve growth factor receptor: Correlation with cholinergic cell bodies and effects of axotomy

1987 • 193 citations

Cholinergic denervation of the rat hippocampus by fimbrial transection leads to a transient accumulation of nerve growth factor (NGF) without change in mRNANGF content

1986 • 188 citations

The Biological Substrates of Alzheimerʼs Disease

1987 • 180 citations

Is Alzheimer disease caused by lack of nerve growth factor?

1983 • 178 citations

In Vitro Evidence for Two Distinct Hippocampal Growth Factors: Basis of Neuronal Plasticity?

1982 • 177 citations

Behavioural and neurochemical effects of chronic intraventricular injections of nerve growth factor in adult rats with fimbria lesions

1985 • 172 citations

The localization and distribution of high affinity β-nerve growth factor binding sites in the central nervous system of the adult rat. A light microscopic autoradiographic study using [125I]β-nerve growth factor

1987 • 169 citations

Developmentally regulated expression of the nerve growth factor receptor gene in the periphery and brain.

1987 • 157 citations

Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: Assessment of potential neurotrophic effects

1988 • 151 citations

Transient expression of NGF-receptor-like immunoreactivity in postnatal rat brain and spinal cord

1988 • 134 citations

Increased beta-nerve growth factor messenger RNA and protein levels in neonatal rat hippocampus following specific cholinergic lesions

1987 • 132 citations

Conditioned medium enhances neuritic outgrowth from rat spinal cord explants

1980 • 131 citations

A cytoarchitectonic and histochemical study of nucleus basalis and associated cell groups in the normal human brain

1984 • 130 citations

Developing dorsal root ganglion neurons require trophic support from their central processes: evidence for a role of retrogradely transported nerve growth factor from the central nervous system to the periphery.

1984 • 125 citations

The Human Gene for the β Subunit of Nerve Growth Factor Is Located on the Proximal Short Arm of Chromosome 1

1983 • 113 citations

Cholinergic System in Behavior: The Search for Mechanisms of Action

1982 • 89 citations

The importance of both early and delayed responses in the biological actions of nerve growth factor

1984 • 88 citations

Nerve growth factor promotes development of the rat septo-hippocampal cholinergic projection in vitro

1987 • 80 citations

Partial reversal of lesion-induced deficits in cortical cholinergic markers by nerve growth factor

1986 • 75 citations

Sympathetic noradrenergic sprouting in response to central cholinergic denervation

1981 • 72 citations

Production and Characterization of Monoclonal Antibodies against Human Malignant Melanoma

1983 • 71 citations

NGF receptor immunoreactivity in rat brain: Topographic distribution and response to entorhinal ablation

1987 • 71 citations

NGF receptor immunoreactivity in aged rat brain

1989 • 66 citations

Failure of nerve growth factor to affect fetal mouse brain stem catecholaminergic neurons in culture

1980 • 62 citations

Alzheimer plaques and cortical cholinergic innervation

1986 • 62 citations

Evaluation of the effects of nerve growth factor and anti-nerve growth factor on the development of central catecholamine-containing neurons

1978 • 59 citations

Development of cholinergic pedunculopontine neurons in vitro: Comparison with Cholinergic septal cells and response to nerve growth factor, ciliary neuronotrophic factor, and retinoic acid

1988 • 57 citations

Effect of thyroid hormone analogs on the activity of choline acetyltransferase in cultures of dissociated septal cells

1986 • 56 citations

Acetylcholine-rich transplants in the hippocampus: influence of intrinsic growth factors and application of nerve growth factor on choline acetyltransferase activity

1985 • 47 citations

Distribution and characteristics of nerve growth factor binding on cholinergic neurons of rat and monkey forebrain

1987 • 42 citations

Properties of receptors for nerve growth factor in the mature rat nervous system

1987 • 36 citations

CHOLINERGIC SYSTEMS IN MAMMALIAN BRAIN IDENTIFIED WITH ANTIBODIES AGAINST CHOLINE ACETYLTRANSFERASE

1985 • 10 citations

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