Nerve Growth Factor and Behavioral Recovery After Brain Damage in Rats

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

1987 • 1,031 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

The expression, localization and functional significance of β-nerve growth factor in the central nervous system

1987 • 496 citations

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

1989 • 470 citations

Nerve growth factor (NGF) stimulation of cholinergic telencephalic neurons in aggregating cell cultures

1982 • 291 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Brain Plasticity, Learning, and Memory

1985 • 268 citations

Delayed treatment with nerve growth factor reverses the apparent loss of cholinergic neurons after acute brain damage

1988 • 233 citations

Rescue of lesioned septal cholinergic neurons by nerve growth factor: specificity and requirement for chronic treatment

1988 • 213 citations

Near-total loss of ‘learning’ and ‘memory’ as a result of combined cholinergic and serotonergic blockade in the rat

1987 • 175 citations

Potential use of nerve growth factor to treat Alzheimer's disease

1989 • 174 citations

Behavioural and neurochemical effects of chronic intraventricular injections of nerve growth factor in adult rats with fimbria lesions

1985 • 172 citations

Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat

1988 • 171 citations

THE NUCLEUS BASALIS IN ALZHEIMER'S DISEASE: CELL COUNTS AND CORTICAL BIOCHEMISTRY

1983 • 157 citations

Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury

1988 • 153 citations

Sympathetic sprouting in the central nervous system: a model for studies of axonal growth in the mature mammalian brain

1987 • 139 citations

Alzheimer's disease and related disorders

1990 • 125 citations

Sympathetic noradrenergic sprouting in response to central cholinergic denervation: A histochemical study of neuronal sprouting in the rat hippocampal formation

1981 • 121 citations

Spatial learning in rats: Correlation with cortical choline acetyltransferase and improvement with NGF following NBM damage

1989 • 117 citations

Sprouting of sympathetic axons in the hippocampal formation: Conditions necessary to elicit ingrowth

1980 • 89 citations

Neurotrophic agents may exacerbate the pathologic cascade of Alzheimer's disease

1989 • 89 citations

Correlation between cortical plaque count and neuronal loss in the nucleus basalis in Alzheimer's disease

1984 • 81 citations

Behavioral deficits after intrahippocampal fetal septal grafts in rats with selective fimbria-fornix lesions

1988 • 78 citations

Long-term effects of nerve growth factor and neural transplants on behavior of rats with medial septal lesions

1986 • 76 citations

NGF treatment promotes development of basal forebrain tissue grafts in the anterior chamber of the eye

1989 • 76 citations

Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth

1989 • 67 citations

NGF-induced remodeling of mature uninjured axon collaterals

1990 • 60 citations

Effect of nerve growth factor on regeneration of goldfish optic axons

1982 • 49 citations

Sprouting of noradrenergic fibers in hippocampus after medial septal lesions: Contributions of the central and peripheral nervous systems

1983 • 45 citations

Nerve growth factor produces a temporary facilitation of recovery from entorhinal cortex lesions

1983 • 38 citations

Nerve growth factor is a neurotrophic factor for forebrain cholinergic neurons; implications for Alzheimer's disease.

1987 • 34 citations

A delayed sprouting response to partial hippocampal deafferentation: Time course of sympathetic ingrowth following fimbrial lesions

1980 • 26 citations

Nerve growth factor can influence growth of cortex cerebri and hippocampus: Evidence from intraocular grafts

1989 • 24 citations

Neonatal brain damage and recovery: Intraventricular injection of NGF at time of injury alters performance of active avoidance

1985 • 23 citations

Nerve growth factor: effects on d-amphetamine-induced activity and brain monoamines

1979 • 21 citations

Is it possible to design rational treatments for the symptoms of Alzheimer's disease?

1985 • 15 citations

Nerve growth factor disrupts metabolism and behavioral performance of intact rats but does not affect recovery from hypothalamic lesions

1980 • 11 citations

Nerve growth factor applications fail to alter behavior of hippocampal-lesioned rats

1979 • 11 citations

Nerve Growth Factor

1988 • 10 citations

Towards trophic factor pharmacology?

1989 • 4 citations

Detrimental actions of neurotrophic agents

1989 • 3 citations

Regional stimulation of cholinergic function by nerve growth factor in an animal model of Alzheimer's disease.

1989 • 3 citations

Effects of Nerve Growth Factor on Cholinergic Neurons of the Rat Forebrain

1985 • 2 citations