Mechanism of Shigella entry into epithelial cells

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants

1998 • 2,394 citations

Supramolecular Structure of the Salmonella typhimurium Type III Protein Secretion System

1998 • 872 citations

S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells

1998 • 804 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.

1994 • 594 citations

A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells

1998 • 582 citations

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

1997 • 564 citations

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

1996 • 522 citations

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

1997 • 424 citations

The secretion of the Shigella flexneri Ipa invasins is activated by epithelial cells and controlled by IpaB and IpaD.

1994 • 362 citations

AB5 toxins

1995 • 236 citations

Interaction of Ipa proteins of Shigella flexneri with alpha5beta1 integrin promotes entry of the bacteria into mammalian cells.

1996 • 223 citations

Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin

1997 • 218 citations

The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells.

1996 • 200 citations

Contact of Shigella with host cells triggers release of Ipa invasins and is an essential function of invasiveness.

1995 • 168 citations

CROSS-TALK BETWEEN BACTERIAL PATHOGENS AND THEIR HOST CELLS

1996 • 153 citations

Rho-dependent membrane folding causes Shigella entry into epithelial cells.

1996 • 141 citations

Invasion and the Pathogenesis of Shigella Infections

1996 • 104 citations

rho, a Small GTP-Binding Protein, Is Essential for Shigella Invasion of Epithelial Cells

1997 • 97 citations

Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent

1997 • 58 citations

Interferon α Inhibits a Src-mediated Pathway Necessary for Shigella-induced Cytoskeletal Rearrangements in Epithelial Cells

1998 • 55 citations

Molecular mechanisms of cell and tissue invasion by Shigella flexneri.

1993 • 22 citations

Bacterial Invasiveness

1996 • 7 citations