Rho-dependent membrane folding causes Shigella entry into epithelial cells.

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.

1989 • 1,268 citations

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1991 • 961 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2

1991 • 669 citations

A new protein of the thick filaments of vertebrate skeletal myofibrils

1973 • 615 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

Asparagine residue in the rho Gene Product Is the Modification Site for Botulinum ADP-ribosyltransferase

1989 • 550 citations

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1989 • 529 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface.

1986 • 374 citations

Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation

1987 • 327 citations

Functional modification of a 21-kilodalton G protein when ADP-ribosylated by exoenzyme C3 of Clostridium botulinum.

1988 • 299 citations

Diphtheria Toxin and Related Proteins

1973 • 285 citations

The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197

1984 • 245 citations

Clostridium botulinum type C produces a novel ADP‐ribosyltransferase distinct from botulinum C2 toxin

1987 • 238 citations

Cloning and expression of an afimbrial adhesin (AFA-I) responsible for P blood group-independent, mannose-resistant hemagglutination from a pyelonephritic Escherichia coli strain

1984 • 238 citations

Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium

1992 • 224 citations

ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells.

1993 • 212 citations

Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.

1993 • 211 citations

Clostridium difficile toxin B acts on the GTP-binding protein Rho.

1994 • 204 citations

Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility.

1994 • 199 citations

Substrate for botulinum ADP-ribosyltransferase, Gb, has an amino acid sequence homologous to a putative rho gene product.

1988 • 178 citations

Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells.

1995 • 174 citations

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.

1994 • 171 citations

Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA

1984 • 170 citations

Botulinum ADP‐ribosyltransferase C3

1988 • 162 citations

The ras-Related Gene rhoB Is an Immediate-Early Gene Inducible by v-Fps, Epidermal Growth Factor, and Platelet-Derived Growth Factor in Rat Fibroblasts

1991 • 162 citations

Purification of the 22 kDa protein substrate of botulinum ADP‐ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP‐binding protein highly homologous to the rho gene product

1989 • 139 citations

Genetic and Molecular Basis of Epithelial Cell Invasion by Shigella Species

1991 • 132 citations

ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1.

1988 • 126 citations

Salmonella typhimurium induces membrane ruffling by a growth factor-receptor-independent mechanism.

1993 • 120 citations

Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues.

1988 • 105 citations

Clostridium botulinum C3 ADP-ribosyltransferase gene. Cloning, sequencing, and expression of a functional protein in Escherichia coli.

1991 • 102 citations

A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly.

1993 • 96 citations

Identification of Two Human Rho GDP Dissociation Inhibitor Proteins Whose Overexpression Leads to Disruption of the Actin Cytoskeleton

1993 • 86 citations

ADP-ribosylation of the ras-related, GTP-binding protein RhoA inhibits lymphocyte-mediated cytotoxicity.

1992 • 82 citations

Purification, renaturation, and reconstituted protein kinase activity of the Sendai virus large (L) protein: L protein phosphorylates the NP and P proteins in vitro

1990 • 69 citations

The GDP-bound form of the small G protein Rac1 p21 is a potent activator of the superoxide-forming NADPH oxidase of macrophages.

1994 • 68 citations

Functional Modification of a 21-Kilodalton G Protein when ADP-Ribosylated by Exoenzyme C3 of Clostridium botulinum

1988 • 66 citations

rac p21 Is Involved in Insulin-Induced Membrane Ruffling and rho p21 Is Involved in Hepatocyte Growth Factor- and 12-O-Tetradecanoylphorbol-13-Acetate (TPA)-Induced Membrane Ruffling in KB Cells

1994 • 39 citations

Function of the post-translationally modified C-terminal region of rho p21.

1992 • 2 citations