Human uroporphyrinogen III synthase: molecular cloning, nucleotide sequence, and expression of a full-length cDNA.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Plasmid screening at high colony density

1980 • 1,100 citations

The tac promoter: a functional hybrid derived from the trp and lac promoters.

1983 • 1,001 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

The GenBank genetic sequence databank

1986 • 464 citations

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

1984 • 379 citations

Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

1988 • 313 citations

Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product.

1982 • 235 citations

Biosynthesis of the pigments of life: formation of the macrocycle

1980 • 224 citations

Tissue‐specific expression of porphobilinogen deaminase

1987 • 209 citations

Sequence homology between two membrane transport ATPases, the Kdp-ATPase of Escherichia coli and the Ca2+-ATPase of sarcoplasmic reticulum.

1984 • 204 citations

The Enzymatic Synthesis of Porphyrins from Porphobilinogen

1958 • 168 citations

Protein Sequence Analysis: Automated Microsequencing

1983 • 163 citations

Nitrogen fixation specific regulatory genes ofKlebsiella pneumoniaeandRhizobium melilotishare homology with the general nitrogen regulatory genentrCofK. pneumoniae

1985 • 160 citations

Molecular cloning and complete primary sequence of human erythrocyte porphobilinogen deaminase

1986 • 141 citations

Human delta-aminolevulinate dehydratase: nucleotide sequence of a full-length cDNA clone.

1986 • 125 citations

The Enzymatic Synthesis of Porphyrins from Porphobilinogen

1953 • 109 citations

Molecular cloning and nucleotide sequence of a complete human uroporphyrinogen decarboxylase cDNA.

1986 • 107 citations

The 3′ untranslated regions of the duplicated human α-globin genes are unexpectedly divergent

1980 • 106 citations

Solubilization and immune-detection of β-galactosidase hybrid proteins carrying foreign antigenic determinants

1983 • 102 citations

Three-dimensional structure of the bifunctional enzyme N-(5'-phosphoribosyl)anthranilate isomerase-indole-3-glycerol-phosphate synthase from Escherichia coli.

1987 • 90 citations

Purification and properties of uroporphyrinogen III synthase (co-synthetase) from Euglena gracilis

1985 • 73 citations

Isolation of recombinant cDNAs encoding chicken erythroid delta-aminolevulinate synthase.

1985 • 71 citations

Molecular cloning and sequencing of the hemD gene of Escherichia coli K-12 and preliminary data on the Uro operon

1987 • 66 citations

Nucleotide sequence of theAgrobacterium tumefaciensoctopine Ti plasmld-encodedtmrgene

1983 • 57 citations

Purification and properties of uroporphyrinogen III synthase from human erythrocytes.

1987 • 52 citations

Coupled-enzyme and direct assays for uroporphyrinogen III synthase activity in human erythrocytes and cultured lymphoblasts

1987 • 48 citations

Computer analysis and structure prediction of nucleic acid and proteins

1984 • 47 citations

Nucleotide sequence for the hemD gene of Escherichia coli encoding uroporphyrinogen III synthase and initial evidence for a hem operon

1988 • 44 citations