Biosynthesis of the pigments of life: formation of the macrocycle

Porphyrins and metalloporphyrins

1976 • 1,942 citations

Porphyrins and Metalloporphyrins

1978 • 1,741 citations

The Enzymatic Synthesis of Porphyrins from Porphobilinogen

1958 • 168 citations

The Enzymatic Synthesis of Porphyrins from Porphobilinogen

1953 • 109 citations

THE PURIFICATION AND PROPERTIES OF UROPORPHYRINOGEN I SYNTHASES AND UROPORPHYRINOGEN III COSYNTHASE. INTERACTIONS BETWEEN THE ENZYMES*

1975 • 82 citations

Studies on porphobilinogen deaminase and uroporphyrinogen III cosynthase from human erythrocytes

1974 • 76 citations

Tetrapyrrylmethane intermediate in the enzymic synthesis of uroporphyrinogen

1972 • 69 citations

Polypyrroles formed from porphobilinogen and amines by uroporphyrinogen synthetase of Rhodopseudomonas spheroides

1973 • 67 citations

The biosynthesis of uroporphyrinogen III: Order of assembly of the four porphobilinogen molecules in the formation of the tetrapyrrole ring

1979 • 60 citations

Order of assembly of the four pyrrole rings during biosynthesis of the natural porphyrins

1979 • 54 citations

Biosynthesis of the natural porphyrins: experiments on the ring-closure steps and with the hydroxy-analogue of porphobilinogen

1979 • 47 citations

Biosynthesis of uroporphyrinogen III from porphobilinogen. Resolution of the enigmatic "switch" mechanism

1976 • 34 citations

Biosynthesis of type-III porphyrins: nature of the rearrangement process

1973 • 30 citations

Biosynthesis of type-III porphyrins: proof of intact ezymic conversion of the head-to-tail bilane into uro'gen-III by intramolecular rearrangement

1978 • 29 citations

Biosynthesis of porphyrins and related macrocycles. Part VI. Nature of the rearrangement process leading to the natural type III porphyrins

1976 • 28 citations

Chemical and enzymic polymerization of 2-aminomethyl-3,3'-carboxymethyl-4,4'-(β-carboxyethyl)dipyrrylmethane

1973 • 25 citations

The enzymatic incorporation of a dipyrrylmethane into uroporphyrinogen III

1972 • 23 citations

Structure of preuroporphyrinogen. Exploration of an enzyme mechanism by carbon-13 and nitrogen-15 NMR spectroscopy

1979 • 21 citations

Zur Uroporphyrinogen-Bildung. Studien mit dem 1 - Aminomethyl-3,8,13,18-tetra( 2-carboxyäthyl)-2,7,12,17-tetracarboxymethylbilinogen

1976 • 18 citations

Biosynthesis of the natural (type-III) porphyrins: proof that rearrangement occurs after head-to-tail bilane formation

1977 • 14 citations

Biosynthesis of porphyrins and related macrocycles. Part VII. Synthesis of specifically labelled [14C1]uroporphyrin-III and of [10,14-13C2]uroporphyrin-III. Conversion of the latter into [10,14-13C2]protoporphyrin-IX; biosynthetic significance of its 13C nuclear magnetic resonance spectrum

1976 • 14 citations

Biosynthesis of natural porphyrins: enzymic experiments on isomeric bilanes

1978 • 11 citations

Intermediates in porphyrin biosynthesis: studies with 14C- and 13C-labelled pyrromethanes

1973 • 11 citations

Mechanistic study of the enzymic incorporation of unrearranged AP·AP pyrromethane into uro'gen-III

1977 • 9 citations

Enzymic formation of the type-III prophyrin macrocycle from unrearranged AP·AP pyrromethane

1977 • 7 citations

Assignment of 13C-signals from the meso-carbons by syntheses of 13C-protoporphyrin-IX dimethyl esters

1973 • 6 citations