Tissue‐specific expression of porphobilinogen deaminase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

The Metabolic Basis of Inherited Disease

1979 • 2,083 citations

Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver

1983 • 469 citations

Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells.

1976 • 318 citations

A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus corresponds to a related pseudogene

1984 • 256 citations

Evaluation of the “scanning model” for initiation of protein synthesis in eucaryotes

1980 • 223 citations

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

1984 • 202 citations

An improved method for detecting foreign DNA in plasmids of Escherichia coli

1979 • 183 citations

Simple, efficientin vitrosynthesis of capped RNA useful for direct expression of cloned eukaryoti genes

1982 • 152 citations

Molecular cloning and complete primary sequence of human erythrocyte porphobilinogen deaminase

1986 • 141 citations

Purification and properties of uroporphyrinogen I synthase from human erythrocytes. Identification of stable enzyme-substrate intermediates.

1980 • 133 citations

Purification and Characterization of Proinsulin mRNA from Rat B‐Cell Tumor

1979 • 86 citations

One gene, but two messenger RNAs encode liver L and red cell L′ pyruvate kinase subunits

1981 • 80 citations

Acute intermittent porphyria: characterization of a novel mutation in the structural gene for porphobilinogen deaminase. Demonstration of noncatalytic enzyme intermediates stabilized by bound substrate.

1985 • 64 citations

Porphyrins and the Porphyrias

2008 • 55 citations

The regulation of heme biosynthesis during erythropoietin-induced erythroid differentiation.

1985 • 36 citations

Molecular cloning of a cDNA sequence complementary to porphobilinogen deaminase mRNA from rat.

1984 • 27 citations

Rare structural variants of human and murine uroporphyrinogen I synthase.

1980 • 9 citations