Interactions of monovalent cations with sodium channels in squid axon. I. Modification of physiological inactivation gating.

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

Inactivation of the sodium channel. II. Gating current experiments.

1977 • 943 citations

Potassium channels as multi-ion single-file pores.

1978 • 816 citations

The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve

1971 • 751 citations

A reinterpretation of mammalian sodium channel gating based on single channel recording

1983 • 675 citations

Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH

1975 • 599 citations

Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

1973 • 540 citations

A quantitative description of membrane current and its application to conduction and excitation in nerve

1990 • 462 citations

Ionic selectivity, saturation, and block in sodium channels. A four-barrier model.

1975 • 400 citations

The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons.

1965 • 345 citations

Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons

1978 • 204 citations

Interactions between quaternary lidocaine, the sodium channel gates, and tetrodotoxin

1979 • 197 citations

Kinetic and pharmacological properties of the sodium channel of frog skeletal muscle.

1976 • 185 citations

Evidence for two types of sodium conductance in axons perfused with sodium fluoride solution

1970 • 166 citations

Influence of membrane thickness and ion concentration on the properties of the gramicidin A channel Autocorrelation, spectral power density, relaxation and single-channel studies

1977 • 162 citations

Destruction of the sodium conductance inactivation by a specific protease in perfused nerve fibres from Loligo.

1976 • 155 citations

Removal of sodium channel inactivation in squid giant axons by n-bromoacetamide.

1978 • 149 citations

Kinetic analysis of pancuronium interaction with sodium channels in squid axon membranes.

1977 • 144 citations

Ionic currents in two strains of rat anterior pituitary tumor cells.

1984 • 142 citations

Relations between the inactivation of sodium channels and the immobilization of gating charge in frog myelinated nerve

1980 • 123 citations

Sodium channel permeation in squid axons. I: Reversal potential experiments.

1980 • 122 citations

Some kinetic and steady-state properties of sodium channels after removal of inactivation.

1981 • 121 citations

Na and Ca channels in a transformed line of anterior pituitary cells.

1984 • 116 citations

Conduction and block by organic cations in a K+-selective channel from sarcoplasmic reticulum incorporated into planar phospholipid bilayers.

1982 • 116 citations

Effects of permeant monovalent cations on end‐plate channels.

1979 • 105 citations

Block of sodium conductance and gating current in squid giant axons poisoned with quaternary strychnine

1979 • 104 citations

The suction pipette method for internal perfusion and voltage clamp of small excitable cells

1980 • 103 citations

Sodium and potassium currents in squid axons perfused with fluoride solutions

1970 • 102 citations

Interaction of permeant ions with channels activated by acetylcholine in Aplysia neurones.

1979 • 101 citations

Sodium channel inactivation in the crayfish giant axon. Must channels open before inactivating?

1981 • 98 citations

Sodium inactivation mechanism modulates QX-314 block of sodium channels in squid axons

1978 • 96 citations

Immobilisation of gating charge by a substance that simulates inactivation

1978 • 95 citations

Magnitude and location of surface charges on Myxicola giant axons.

1975 • 85 citations

Sodium channel selectivity. Dependence on internal permeant ion concentration.

1976 • 77 citations

Rate constants associated with changes in sodium conductance in axons perfused with sodium fluoride

1970 • 75 citations

Block of endplate channels by permeant cations in frog skeletal muscle.

1981 • 72 citations

Modifications of sodium channel gating in Myxicola giant axons by deuterium oxide, temperature, and internal cations

1979 • 69 citations

Arginine-specific reagents remove sodium channel inactivation

1978 • 69 citations

Properties of amphotericin B channels in a lipid bilayer

1977 • 65 citations

The effect of tetramethylammonium on single sodium channel currents

1981 • 62 citations

Simulation of Na channel inactivation by thiazine dyes.

1982 • 60 citations

Dynamics of 9-aminoacridine block of sodium channels in squid axons.

1979 • 59 citations

Interactions of monovalent cations with sodium channels in squid axon. I. Modification of physiological inactivation gating.

1985 • 48 citations

Selective modification of sodium channel gating in lobster axons by 2, 4, 6-trinitrophenol: Evidence for two inactivation mechanisms.

1975 • 47 citations

Interaction of n-alkylguanidines with the sodium channels of squid axon membrane.

1980 • 44 citations

The permeability of the sodium channel in Myxicola to the alkali cations.

1976 • 39 citations

Incomplete inactivation of sodium currents in nonperfused squid axon

1980 • 26 citations

Tetramethylammonium ions alter sodium-channel gating in Myxicola

1983 • 18 citations

Interaction of deoxycholate with the sodium channel of squid axon membranes.

1980 • 15 citations

Internal cesium alters sodium inactivation in Myxicola

1978 • 11 citations