Analysis of heparin, α-dystroglycan and sulfatide binding to the G domain of the laminin α1 chain by site-directed mutagenesis 1 1Edited by A. R. Fersht

A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin

1993 • 1,352 citations

Structure and function of laminin: anatomy of a multidomain glycoprotein

1990 • 812 citations

Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin

1992 • 669 citations

The Reaction of Phenylglyoxal with Arginine Residues in Proteins

1968 • 636 citations

Tetranitromethane. A Reagent for the Nitration of Tyrosyl Residues in Proteins^*

1966 • 635 citations

Dystroglycan Is Essential for Early Embryonic Development: Disruption of Reichert's Membrane in Dag1-Null Mice

1997 • 529 citations

Dystroglycan-α, a dystrophin-associated glycoprotein, is a functional agrin receptor

1994 • 509 citations

Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.

1988 • 486 citations

Laminin-nidogen complex. Extraction with chelating agents and structural characterization

1987 • 453 citations

Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α-dystroglycan and several extracellular matrix proteins

1999 • 448 citations

The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.

1991 • 446 citations

Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.

1990 • 405 citations

Structures of Sialylated O-Linked Oligosaccharides of Bovine Peripheral Nerve α-Dystroglycan

1997 • 388 citations

A Role for Dystroglycan in Basement Membrane Assembly

1998 • 387 citations

Structure and distribution of modules in extracellular proteins

1996 • 322 citations

Protease Resistance and Conformation of Laminin

1982 • 313 citations

[11] Methods for investigating the essential groups for enzyme activity

1957 • 305 citations

Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of laminin

1993 • 282 citations

A single EGF-like motif of laminin is responsible for high affinity nidogen binding.

1993 • 269 citations

Dystroglycan: an extracellular matrix receptor linked to the cytoskeleton

1996 • 264 citations

Properties of the extracellular calcium binding module of the proteoglycan testican

1997 • 247 citations

Molecular Cloning of a Novel Laminin Chain, α5, and Widespread Expression in Adult Mouse Tissues

1995 • 246 citations

The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.

1987 • 243 citations

Alternative Splicing of Agrin Alters Its Binding to Heparin, Dystroglycan, and the Putative Agrin Receptor

1996 • 223 citations

Guidebook to the extracellular matrix and adhesion proteins

1994 • 216 citations

Binding of nidogen and the laminin‐nidogen complex to basement membrane collagen type IV

1989 • 203 citations

Basement‐membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core

1992 • 193 citations

Non-muscle alpha-dystroglycan is involved in epithelial development.

1995 • 186 citations

Neural Targeting of Mycobacterium leprae Mediated by the G Domain of the Laminin-α2 Chain

1997 • 179 citations

[22] Antibodies to collagens and procollagens

1982 • 164 citations

Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain

1990 • 163 citations

The C‐Terminal Domain V of Perlecan Promotes β1 Integrin‐Mediated Cell Adhesion, Binds Heparin, Nidogen and Fibulin‐2 and Can be Modified by Glycosaminoglycans

1997 • 153 citations

Dystroglycan is a binding protein of laminin and merosin in peripheral nerve

1994 • 151 citations

Electron microscopic evidence for a mucin‐like region in chick muscle α‐dystroglycan

1995 • 139 citations

Agrin Is a High-affinity Binding Protein of Dystroglycan in Non-muscle Tissue

1998 • 136 citations

Cloning and Complete Primary Structure of the Mouse Laminin α3 Chain

1995 • 124 citations

Monoclonal antibodies against laminin A chain fragment E3 and their effects on binding to cells and proteoglycan and on kidney development

1992 • 122 citations

Functions of agrin and agrin-related proteins

1993 • 119 citations

Structure and distribution of N-linked oligosaccharide chains on various domains of mouse tumour laminin

1988 • 119 citations

Dystroglycan Is a Dual Receptor for Agrin and Laminin-2 in Schwann Cell Membrane

1996 • 114 citations

Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1623]

1993 • 110 citations

Sequence of extracellular mouse protein BM‐90/fibulin and its calcium‐dependent binding to other basement‐membrane ligands

1993 • 103 citations

Recombinant expression and properties of the human calcium‐binding extracellular matrix protein BM‐40

1991 • 99 citations

Sex hormone‐binding globulin, androgen‐binding protein, and vitamin K‐dependent protein S are homologous to laminin A, merosin, and Drosophila crumbs protein

1992 • 97 citations

Comparison of the specificities of laminin, thrombospondin, and von Willebrand factor for binding to sulfated glycolipids.

1986 • 96 citations

Expression of fibulin-2 by fibroblasts and deposition with fibronectin into a fibrillar matrix

1996 • 95 citations

Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunit.

1991 • 91 citations

Heparin modulation of laminin polymerization.

1990 • 88 citations

Two non-contiguous regions contribute to nidogen binding to a single EGF-like motif of the laminin gamma 1 chain.

1994 • 88 citations

Cloning and expression of laminin α2 chain (M-chain) in the mouse

1995 • 84 citations

Structural study of long arm fragments of laminin

1988 • 82 citations

Agrin Binding to α-Dystroglycan

1996 • 81 citations

Differential Heparin Inhibition of Skeletal Muscle α-Dystroglycan Binding to Laminins

1996 • 81 citations

Recombinant laminin G domain mediates myoblast adhesion and heparin binding.

1993 • 80 citations

Site-directed mutagenesis and structural interpretation of the nidogen binding site of the laminin gamma1 chain.

1996 • 77 citations

Structural analysis and proteolytic processing of recombinant G domain of mouse laminin α2 chain

1998 • 74 citations

In vitro synthesis of novel genes: mutagenesis and recombination by PCR.

1994 • 74 citations

The N‐terminal Region of α‐Dystroglycan is an Autonomous Globular Domain

1997 • 64 citations

Binding and calcium-induced aggregation of laminin onto lipid bilayers.

1991 • 63 citations

Changes in Calcium and Collagen IV Binding Caused by Mutations in the EF Hand and Other Domains of Extracellular Matrix Protein BM-40 (SPARC, Osteonectin)

1994 • 63 citations

Sulfatide-binding domain of the laminin A chain.

1990 • 58 citations

[22] Electron microscopy of extracellular matrix components

1994 • 51 citations

Structural Properties of Recombinant Domain III-3 of Perlecan Containing a Globular Domain Inserted into an Epidermal-Growth-Factor-Like Motif

1995 • 47 citations

Inhibition of glycosaminoglycan modification of perlecan domain I by site‐directed mutagenesis changes protease sensitivity and laminin‐1 binding activity

1998 • 40 citations

The complete cDNA coding sequence and tissue-specific expression of the mouse laminin α4 chain

1996 • 39 citations

Targeting the glycosaminoglycan-binding sites on proteins

1994 • 38 citations

Cranin interacts specifically with the sulfatide‐binding domain of laminin

1993 • 37 citations

Localization of Heparin Binding Activity in Recombinant Laminin G Domain

1997 • 33 citations

Structural Properties of Recombinant Domain III-3 of Perlecan Containing a Globular Domain Inserted into an Epidermal-Growth-Factor-Like Motif

1995 • 33 citations

A family of laminin‐related proteins controlling ectodermal differentiation in Drosophila

1992 • 23 citations

Structure and Function of the Laminin‐Nidogen Complex

1990 • 22 citations

Sequence analysis suggests the presence of an IG-like domain in the N-terminal region of α-dystroglycan which was crystallized after mutation of a protease susceptible site (Arg168 → His)

1998 • 17 citations

Guidebook to the extracellular matrix and adhesion proteins

1994 • 17 citations