Inhibition of glycosaminoglycan modification of perlecan domain I by site‐directed mutagenesis changes protease sensitivity and laminin‐1 binding activity
Data up to Jan 2025
Total Citations Per Year
Abstract
References (24)
The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases
1996 • 601 citations
Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis
1994 • 541 citations
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.
1991 • 446 citations
Heparan sulfate: a piece of information
1996 • 441 citations
The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices
1994 • 384 citations
Properties of the extracellular calcium binding module of the proteoglycan testican
1997 • 247 citations
Fibroblast growth factors and their receptors
1997 • 204 citations
Binding of nidogen and the laminin‐nidogen complex to basement membrane collagen type IV
1989 • 203 citations
Basement‐membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core
1992 • 193 citations
Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan.
1992 • 180 citations
Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane
1987 • 167 citations
Proteoglycans of basement membranes
1993 • 166 citations
The C‐Terminal Domain V of Perlecan Promotes β1 Integrin‐Mediated Cell Adhesion, Binds Heparin, Nidogen and Fibulin‐2 and Can be Modified by Glycosaminoglycans
1997 • 153 citations
Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin
1998 • 143 citations
The SEA module: A new extracellular domain associated with O‐glycosylation
1995 • 143 citations
Heparan sulphate
1997 • 114 citations
Identification of Sites in Domain I of Perlecan That Regulate Heparan Sulfate Synthesis
1997 • 113 citations
The N‐terminal globular domain of the laminin α1 chain binds to α1β1 and α2β1 integrins and to the heparan sulfate‐containing domains of perlecan
1998 • 96 citations
Two non-contiguous regions contribute to nidogen binding to a single EGF-like motif of the laminin gamma 1 chain.
1994 • 88 citations
Characterization of Recombinant Perlecan Domain I and Its Substitution by Glycosaminoglycans and Oligosaccharides
1997 • 73 citations
Basement membranes
1987 • 71 citations
Structural basis of beta 1 integrin-mediated cell adhesion to a large heparan sulfate proteoglycan from basement membranes.
1993 • 48 citations
Formation of Heparan Sulfate or Chondroitin/Dermatan Sulfate on Recombinant Domain I of Mouse Perlecan Expressed in Chinese Hamster Ovary Cells
1995 • 43 citations
Expression and Characterization of Human Perlecan Domains I and II Synthesized by Baculovirus‐Infected Insect Cells
1996 • 30 citations