Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain
Data up to Jan 2025
Total Citations Per Year
Abstract
References (41)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.
1987 • 5,066 citations
New Perspectives in Cell Adhesion: RGD and Integrins
1987 • 4,835 citations
Structure and biological activity of basement membrane proteins
1989 • 967 citations
Structure and function of laminin: anatomy of a multidomain glycoprotein
1990 • 812 citations
Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix
1981 • 666 citations
The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.
1984 • 634 citations
A Synthetic Peptide Containing the IKVAV Sequence from the A Chain of Laminin Mediates Cell Attachment, Migration, and Neurite Outgrowth
1989 • 623 citations
Role of laminin a chain in the development of epithelial cell polarity
1988 • 488 citations
Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.
1988 • 486 citations
Biological activities of laminin
1985 • 470 citations
Laminin-nidogen complex. Extraction with chelating agents and structural characterization
1987 • 453 citations
Adhesion and cytoskeletal organisation of fibroblasts in response to fibronectin fragments.
1986 • 429 citations
Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.
1990 • 405 citations
Merosin, a tissue-specific basement membrane protein, is a laminin-like protein.
1990 • 398 citations
Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.
1987 • 381 citations
Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function
1988 • 372 citations
Domains of laminin with growth-factor activity
1989 • 341 citations
Mapping of domains in human laminin using monoclonal antibodies: localization of the neurite-promoting site.
1986 • 318 citations
Protease Resistance and Conformation of Laminin
1982 • 313 citations
The laminin B2 chain has a multidomain structure homologous to the B1 chain.
1987 • 307 citations
Cell attachment properties of collagen type VI and arg-gly-asp dependent binding to its α2(VI) and α3(VI) chains
1989 • 252 citations
The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.
1987 • 243 citations
Evidence for coiled-coil alpha-helical regions in the long arm of laminin.
1985 • 195 citations
Two distinct cell-binding domains in laminin can independently promote nonneuronal cell adhesion and spreading [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]
1987 • 195 citations
Primary sequence of a motor neuron-selective adhesive site in the synaptic basal lamina protein s-laminin
1989 • 194 citations
The E8 subfragment of laminin promotes locomotion of myoblasts over extracellular matrix.
1989 • 193 citations
Subunit structure of a laminin-binding integrin and localization of its binding site on laminin
1989 • 172 citations
Identification of a neurite outgrowth‐promoting domain of laminin using synthetic peptides
1989 • 167 citations
Antibody to integrin α6 subunit specifically inhibits cell-binding to laminin fragment 8
1990 • 161 citations
Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies.
1988 • 155 citations
Isolation and characterization of rat schwannoma neurite-promoting factor: evidence that the factor contains laminin
1985 • 152 citations
Identification of the Arg‐Gly‐Asp sequence in laminin A chain as a latent cell‐binding site being exposed in fragment P1
1990 • 150 citations
Human laminin isolated in a nearly intact, biologically active form from placenta by limited proteolysis.
1983 • 147 citations
Laminin a chain synthetic peptide which supports neurite outgrowth
1989 • 122 citations
The high‐affinity binding of laminin to cells
1989 • 83 citations
Structural study of long arm fragments of laminin
1988 • 82 citations
Human laminin: cloning and sequence analysis of cDNAs encoding A, B1 and B2 chains, and expression of the corresponding genes in human skin and cultured cells.
1989 • 75 citations
The neurite-promoting domain of human laminin promotes attachment and induces characteristic morphology in non-neuronal cells
1988 • 65 citations
Evidence for a specific mechanism of laminin assembly
1990 • 47 citations
Structure and Function of the Laminin‐Nidogen Complex
1990 • 22 citations