Molecular Mechanisms Underlying a Unique Intermediate Phase of Memory in Aplysia

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

1996 • 1,750 citations

Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory

1997 • 1,228 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

Genetic dissection of consolidated memory in Drosophila

1994 • 901 citations

Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP

1994 • 889 citations

Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

1988 • 800 citations

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia

1986 • 767 citations

Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation

1990 • 741 citations

Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage

1997 • 738 citations

CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila

1995 • 639 citations

A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic Facilitation

1983 • 620 citations

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

1993 • 549 citations

A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis

1999 • 510 citations

cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase

1994 • 501 citations

Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats

1997 • 500 citations

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

1980 • 380 citations

Differential Classical Conditioning of a Defensive Withdrawal Reflex in Aplysia californica

1983 • 364 citations

CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation

1998 • 363 citations

Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin

1998 • 355 citations

Monosynaptic connections made by the sensory neurons of the gill- and siphon-withdrawal reflex in Aplysia participate in the storage of long-term memory for sensitization

1985 • 334 citations

Psychobiology of memory: Towards a model of memory formation

1977 • 295 citations

The retention of an incompletely learned avoidance response.

1957 • 274 citations

cAMP Evokes Long-Term Facilitation in Aplysia Sensory Neurons That Requires New Protein Synthesis

1988 • 265 citations

The effects of biogenic amines on conditioned and unconditioned responses to olfactory stimuli in the honeybeeApis mellifera

1982 • 261 citations

Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in aplysia sensory neurons

1992 • 253 citations

Prolonged Activation of cAMP-Dependent Protein Kinase during Conditioning Induces Long-Term Memory in Honeybees

2000 • 248 citations

Inhibitor of protein synthesis blocks longterm behavioral sensitization in the isolated gill‐withdrawal reflex of Aplysia

1989 • 240 citations

A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia

1995 • 209 citations

Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia

1982 • 207 citations

Long-Term Synaptic Facilitation in the Absence of Short-Term Facilitation in Aplysia Neurons

1993 • 197 citations

Identified serotonergic neurons LCB1 and RCB1 in the cerebral ganglia of Aplysia produce presynaptic facilitation of siphon sensory neurons

1989 • 196 citations

Mechanoafferent neurons innervating tail of Aplysia. II. Modulation by sensitizing stimulation

1983 • 194 citations

Short-term, intermediate-term, and long-term memories

1993 • 191 citations

Role of Transforming Growth Factor-β in Long-Term Synaptic Facilitation in Aplysia

1997 • 189 citations

Involvement of hippocampal D1/D5 receptor-cAMP signaling pathways in a late memory consolidation phase of an aversively-motivated task in rats

1997 • 188 citations

Cellular Correlates of Long-Term Sensitization inAplysia

1998 • 178 citations

Second messengers involved in the two processes of presynaptic facilitation that contribute to sensitization and dishabituation in Aplysia sensory neurons.

1990 • 173 citations

Parallel Molecular Pathways Mediate Expression of Distinct Forms of Intermediate-Term Facilitation at Tail Sensory–Motor Synapses in Aplysia

2000 • 142 citations

Serotonin Induces Temporally and Mechanistically Distinct Phases of Persistent PKA Activity in Aplysia Sensory Neurons

1998 • 129 citations

Interneurons involved in mediation and modulation of gill-withdrawal reflex in Aplysia. I. Identification and characterization.

1981 • 125 citations

Retention of an incompletely learned avoidance response: Some further analyses.

1963 • 123 citations

Levels of Serotonin in the Hemolymph ofAplysiaAre Modulated by Light/Dark Cycles and Sensitization Training

1999 • 120 citations

Involvement of Presynaptic and Postsynaptic Mechanisms in a Cellular Analog of Classical Conditioning atAplysiaSensory-Motor Neuron Synapses in Isolated Cell Culture

1998 • 112 citations

Dynamics of Induction and Expression of Long-Term Synaptic Facilitation inAplysia

1996 • 109 citations

Pharmacological Dissociation of Modulatory Effects of Serotonin in Aplysia Sensory Neurons

1991 • 96 citations

Genetic Dissection of Memory Formation in Drosophila melanogaster

1990 • 95 citations

Structure of the network mediating siphon-elicited siphon withdrawal in Aplysia

1995 • 85 citations

A Cellular Mechanism of Classical Conditioning in Aplysia

1984 • 85 citations

Coincident Induction of Long-Term Facilitation in Aplysia : Cooperativity Between Cell Bodies and Remote Synapses

1999 • 80 citations

Long-Term Synaptic Changes Produced by a Cellular Analog of Classical Conditioning in Aplysia

1990 • 76 citations

Activity-dependent potentiation of recurrent inhibition: a mechanism for dynamic gain control in the siphon withdrawal reflex of Aplysia

1993 • 73 citations

Behavioural stages in memory formation

1979 • 72 citations

Induction of long-term facilitation in Aplysia sensory neurons by local application of serotonin to remote synapses.

1993 • 71 citations

The Contribution of Facilitation of Monosynaptic PSPs to Dishabituation and Sensitization of theAplysiaSiphon Withdrawal Reflex

1999 • 65 citations

Biochemical Pathways by Which Serotonin Regulates Translation in the Nervous System of Aplysia

1998 • 62 citations

Long-term regulation of neuronal high-affinity glutamate and glutamine uptake in Aplysia

2000 • 60 citations

Identification and characterization of a multifunction neuron contributing to defensive arousal in Aplysia

1993 • 58 citations

Protein Synthesis–Dependent and mRNA Synthesis–Independent Intermediate Phase of Memory in Hermissenda

1999 • 43 citations

Memory consolidation: Further evidence for the four-phase model from the time-courses of diethyldithiocarbamate and ethacrinic acid amnesias

1982 • 39 citations

Long-Term Enhancement but Not Short-Term inHermissendaIs Dependent upon mRNA Synthesis

1997 • 39 citations

Contextual Modulation of Memory Consolidation

2000 • 39 citations

Variations in Retention Performance during Long Term Memory Formation

1971 • 37 citations

Site Specificity of Short-Term and Long-Term Habituation in the Tail-Elicited Siphon Withdrawal Reflex ofAplysia

1996 • 37 citations

One-Trial Learning and Biphasic Time Course of Performance in the Goldfish

1971 • 35 citations

Transient hypoxic-amnesia: Evidence for a triphasic memory-consolidating mechanism with parallel processing

1978 • 34 citations

Motor neuronal control of tail-directed and head-directed siphon responses in Aplysia californica

1995 • 29 citations

Multiple-Phase Model of Memory Consolidation Confirmed by Behavioral and Pharmacological Analyses of Operant Conditioning in Drosophila

1998 • 28 citations

A single identified interneuron gates tail-shock induced inhibition in the siphon withdrawal reflex of Aplysia

1995 • 23 citations

Biphasicity of the incubation curve

1970 • 17 citations

Serial position-reversal learning in the rat: A preliminary analysis of training criteria.

1963 • 13 citations

A Musical Investigation of the Kamin Effect

1973 • 7 citations