Statistical comparison of established T-cell epitope predictors against a large database of human and murine antigens

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1990 • 906 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

A sequence pattern common to T cell epitopes.

1988 • 623 citations

T-cell antigenic sites tend to be amphipathic structures.

1985 • 527 citations

Prediction of immunodominant helper T cell antigenic sites from the primary sequence.

1987 • 483 citations

Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.

1994 • 345 citations

Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning.

1994 • 304 citations

Production of soluble MHC class II proteins with covalently bound single peptides

1994 • 302 citations

Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I.

1993 • 280 citations

Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants.

1995 • 271 citations

Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

1988 • 264 citations

T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones.

1992 • 244 citations

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.

1991 • 242 citations

Chemometrics: applications of mathematics and statistics to laboratory systems

1991 • 231 citations

Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

1989 • 225 citations

Several HLA alleles share overlapping peptide specificities.

1995 • 197 citations

Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients.

1993 • 196 citations

Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides.

1993 • 169 citations

HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.

1993 • 154 citations

T cell epitope specificity in human allergic and nonallergic subjects to bee venom phospholipase A2.

1993 • 153 citations

Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans

1988 • 146 citations

Identification of two promiscuous T cell epitopes from tetanus toxin

1990 • 145 citations

T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes.

1991 • 138 citations

Induction of rabies virus-specific T-helper cells by synthetic peptides that carry dominant T-helper cell epitopes of the viral ribonucleoprotein

1989 • 132 citations

T cell epitopes of house dust mite major allergen Der p II.

1993 • 124 citations

Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme

1989 • 111 citations

Functional analysis of DR17(DR3)-restricted mycobacterial T cell epitopes reveals DR17-binding motif and enables the design of allele-specific competitor peptides.

1992 • 105 citations

Mapping the major human T helper epitopes of tetanus toxin. The emerging picture.

1993 • 104 citations

Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.

1991 • 100 citations

T and B cell epitope mapping of SM23, an integral membrane protein of Schistosoma mansoni.

1992 • 95 citations

Use of Prior Vaccinations for the Development of New Vaccines

1990 • 95 citations

Analysis of human T cell responses to the group II allergen of Dermatophagoides species: Localization of major antigenic sites

1993 • 94 citations

Hydrophobic strip-of-helix algorithm for selection of T cell-presented peptides☆

1987 • 91 citations

Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes

1993 • 83 citations

T cell multideterminant regions in the human immunodeficiency virus envelope: toward overcoming the problem of major histocompatibility complex restriction

1989 • 75 citations

Epitopes recognized by human t lymphocytes on malaria circumsporozoite protein

1988 • 74 citations

Recognition of T cell epitopes and lymphokine secretion by rye grass allergen Lolium perenne I-specific human T cell clones.

1994 • 74 citations

Minute quantities of a single immunodominant foreign epitope are presented as large nested sets by major histocompatibility complex class II molecules

1993 • 73 citations

DRB1*0301 molecules recognize a structural motif distinct from the one recognized by most DR beta 1 alleles.

1992 • 69 citations

Multiple T cell specificities for Bet v I, the major birch pollen allergen, within single individuals. Studies using specific T cell clones and overlapping peptides

1993 • 58 citations

Mapping human T cell epitopes on phospholipase A2: The major bee-venom allergen+

1992 • 54 citations

Genetic restriction and fine specificity of human T cell clones reactive with rabies virus.

1988 • 51 citations

Use of synthetic peptides to establish anti-human acetylcholine receptor CD4+ cell lines from myasthenia gravis patients.

1990 • 50 citations

Analysis of human T-cell epitopes in the 19,000 MW antigen of Mycobacterium tuberculosis: influence of HLA-DR.

1991 • 48 citations

House dust mite allergy: from T‐cell epitopes to immuno‐therapy

1993 • 47 citations

Processing of endogenously synthesized hen egg-white lysozyme retained in the endoplasmic reticulum or in secretory form gives rise to a similar but not identical set of epitopes recognized by class II-restricted T cells.

1993 • 45 citations

Human recognition of T cell epitopes on the Plasmodium vivax circumsporozoite protein.

1992 • 42 citations

Analysis of human t cell response to two plasmodium falciparum merozoite surface antigens

1989 • 42 citations

Characterization of T-cell responses to the house dust mite allergen Der p II in mice. Evidence for major and cryptic epitopes.

1993 • 34 citations

Mapping human T cell epitopes in Leishmania gp63: identification of cross-reactive and species-specific epitopes.

1993 • 34 citations

T cell recognition of Neisseria meningitidis class 1 outer membrane proteins. Identification of T cell epitopes with selected synthetic peptides and determination of HLA restriction elements.

1991 • 33 citations

Human T- and B-cell epitopes of E1 glycoprotein of rubella virus

1993 • 27 citations

Myasthenia gravis. CD4+ T epitopes on the embryonic gamma subunit of human muscle acetylcholine receptor.

1992 • 27 citations

T cell epitope analysis with peptides simultaneously synthesized on cellulose membranes: Fine mapping of two DQ dependent epitopes

1994 • 27 citations

Epitope analysis of the T cell response to a complex antigen: Proliferative responses to human rhinovirus capsids

1993 • 23 citations

Mapping of T cell epitopes of the major fraction of rye grass using peripheral blood mononuclear cells from atopics and non‐atopics. II. Isoallergen clone 5A of Loliuum perenne group I (Lol p I)

1994 • 23 citations

Identification of helper T cell antigenic sites in mice from the haemagglutinin glycoprotein of measles virus

1993 • 21 citations

Identification of B- and T-cell epitopes within the MTP40 protein of Mycobacterium tuberculosis and their correlation with the disease course

1991 • 21 citations

Mapping human T cell epitopes in leishmania gp63. Identification of cross-reactive and species-specific epitopes.

1993 • 21 citations

Multiple T cell antigenic determinants identified within a limited region of the horse cytochrome c molecule

1987 • 20 citations

Comparison of three related methods to select T cell-presented sequences of protein antigens

1990 • 18 citations

Identification of B-cell epitopes on the S4 subunit of pertussis toxin

1993 • 15 citations

T‐Helper‐Cell Determinants in Protein Antigens are Preferentially Located in Cysteine‐Rich Antigen Segments Resistant to Proteolytic Cleavage by Cathepsin B, L, and D

1991 • 14 citations

Identification of human T-cell epitopes on the S4 subunit of pertussis toxin

1992 • 13 citations

Use of synthetic peptides to map regions of rubella virus capsid protein recognized by human T lymphocytes

1994 • 11 citations

T‐Cell Epitopes on the Human Acetylcholine Receptor α‐Subunit Residues 10‐84 in Myasthenia Gravis

1992 • 7 citations

The Leeuwenhoek Lecture, 1993. Peptide vaccines: dream or reality?

1994 • 7 citations

Identification of Mengo Virus T Helper Cell Epitopes

1994 • 5 citations

Epitopes recognized by HIV-SF2 nef-specific CD4+ T-cell clones generated from HIV-1-uninfected donors

1994 • 4 citations

Deleted Work

1955 • 0 citations