Epitopes recognized by HIV-SF2 nef-specific CD4+ T-cell clones generated from HIV-1-uninfected donors

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Qualitative Analysis of Immune Function in Patients with the Acquired Immunodeficiency Syndrome

1985 • 737 citations

Nucleotide Sequence and Expression of an AIDS-Associated Retrovirus (ARV-2)

1985 • 718 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

1986 • 673 citations

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1987 • 523 citations

Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients

1986 • 513 citations

Regulatory pathways governing HIV-1 replication

1989 • 401 citations

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion

1988 • 372 citations

Nef Protein of HIV-1 Is a Transcriptional Repressor of HIV-1 LTR

1988 • 366 citations

LONG LATENCY PRECEDES OVERT SEROCONVERSION IN SEXUALLY TRANSMITTED HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

1987 • 348 citations

Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication.

1987 • 310 citations

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

1988 • 294 citations

Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1.

1989 • 266 citations

Human immunodeficiency virus type 1 negative factor is a transcriptional silencer.

1989 • 243 citations

Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.

1989 • 227 citations

Analysis of HLA-DP Allelic Sequence Polymorphism Using the In Vitro Enzymatic Amplification of DPα and DPβ Loci

1989 • 218 citations

A new HTLV-III/LAV Encoded Antigen Detected by Antibodies from AIDS Patients

1985 • 212 citations

Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens.

1984 • 209 citations

Differential Effects of nef on HIV Replication: Implications for Viral Pathogenesis in the Host

1989 • 183 citations

Analysis of HLA-DP allelic sequence polymorphism using the in vitro enzymatic DNA amplification of DP-alpha and DP-beta loci.

1988 • 179 citations

Human cytotoxic T cell clones directed against herpes simplex virus-infected cells. I. Lysis restricted by HLA class II MB and DR antigens.

1984 • 174 citations

The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

1990 • 159 citations

Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteins

1989 • 152 citations

Induction of CD4⁺Human Cytolytic T Cells Specific for HIV-Infected Cells by a Gp160 Subunit Vaccine

1990 • 148 citations

Six epitopes reacting with human cytotoxic CD8+ T cells in the central region of the HIV-1 NEF protein.

1991 • 138 citations

Vaccines 90: Modern approaches to new vaccines including prevention of AIDS

1991 • 137 citations

Mapping the fine specificity of a cytolytic T cell response to HIV-1 nef protein.

1990 • 133 citations

Yeast genetic engineering

1990 • 132 citations

Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clones

1988 • 129 citations

Characterization of the cysteinyl-containing peptides of the gamma subunit of coupling factor 1.

1984 • 119 citations

Expression of specific cytolytic activity by H-2I region-restricted, influenza virus-specific T lymphocyte clones.

1985 • 119 citations

The human MHC-restricted cellular response to herpes simplex virus type 1 is mediated by CD4+, CD8- T cells and is restricted to the DR region of the MHC complex.

1988 • 110 citations

Recognition of hepatitis B surface antigen by human T lymphocytes. Proliferative and cytotoxic responses to a major antigenic determinant defined by synthetic peptides.

1988 • 107 citations

The Sixth International Conference on AIDS.

1990 • 105 citations

Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.

1991 • 100 citations

Proliferative and cytotoxic T cells to AIDS virus glycoproteins in chimpanzees immunized with a recombinant vaccinia virus expressing AIDS virus envelope glycoproteins.

1987 • 99 citations

Influenza virus-specific human cytotoxic T cell clones: Heterogeneity in antigenic specificity and restriction by class II MHC products

1984 • 92 citations

Carboxyl-terminal and central regions of human immunodeficiency virus-1 NEF recognized by cytotoxic T lymphocytes from lymphoid organs. An in vitro limiting dilution analysis.

1992 • 91 citations

An antigenic peptide of the HIV‐1 NEF protein recognized by cytotoxic T lymphocytes of seropositive individuals in association with different HLA‐B

1989 • 91 citations

Regulation of AIDS virus expression

1986 • 81 citations

Antibodies to thenefProtein and tonefPeptides in HIV-1—Infected Seronegative Individuals

1989 • 72 citations

HLA-DR-restricted cytotoxicity of cytomegalovirus-infected monocytes mediated by Leu-3-positive T cells.

1986 • 68 citations

Sequences outside a minimal immunodominant site exert negative effects on recognition by staphylococcal nuclease-specific T cell clones.

1989 • 68 citations

Antigenicity and immunogenicity of domains of the human immunodeficiency virus (HIV) envelope polypeptide expressed in the yeast Saccharomyces cerevisiae

1987 • 61 citations

Specific lysis of varicella zoster virus-infected B lymphoblasts by human T cells

1986 • 56 citations

Characterization of a conserved T cell epitope in HIV-1 gp41 recognized by vaccine-induced human cytolytic T cells.

1991 • 56 citations

Varicella-zoster virus-specific cytotoxic T lymphocytes (Tc): detection and frequency analysis of HLA class I-restricted Tc in human peripheral blood

1987 • 54 citations

Human T cell clones present antigen.

1989 • 53 citations

Cytolytic activity of antigen-specific T cells with helper phenotype.

1986 • 50 citations

Cloned protein antigen-specific, Ia-restricted T cells with both helper and cytolytic activities: Mechanisms of activation and killing

1987 • 46 citations

The immunobiology of T cell responses to Mls-locus-disparate stimulator cells. III. Helper and cytolytic functions of cloned, Mls-reactive T cell lines.

1986 • 45 citations

Multiple subsets of HIV‐specific cytotoxic T lymphocytes in humans and in mice

1989 • 44 citations

Antigenic epitopes of NEF proteins from different HIV-1 strains as recognized by Sera from patients with manifest and latent HIV infection

1990 • 41 citations

Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.

1990 • 38 citations

Reversal of HLA restriction by a point mutation in an antigenic peptide

1989 • 36 citations

Immunogenicity of the Human Immunodeficiency Virus (HIV) RecombinantnefGene Product. Mapping of T-Cell and B-Cell Epitopes in Immunized Chimpanzees

1990 • 36 citations

Hapten-specific, class II-restricted killing by cloned T cells: direct lysis and production of a cytotoxic factor.

1986 • 25 citations

Ir Genes: Antigen-Specific Genetic Regulation of the Immune Response

1987 • 24 citations

Carboxyl-terminal and Central Regions of Human Immunodeficiency Virus-1 NEF Recognized by Cytotoxic T Lymphocytes from Lymphoid Organs

1992 • 22 citations

Helper or cytolytic functions can be selectively induced in bifunctional T cell clones.

1990 • 20 citations

Epitopes of the HIV-1-Negative Factor (nef) Reactive with Murine Monoclonal Antibodies and Human HIV-1-Positive Sera

1991 • 19 citations

Identification of human immunodeficiency virus (HIV) envelope type-specific T helper cells in an HIV-infected individual.

1988 • 18 citations

Determination of B-cell epitopes of nef HIV-I protein: Immunogenicity related to their structure

1992 • 18 citations

Antibodies to recombinant HIV-1 nef protein detected in HIV-1 infection as well as in nonrisk individuals.

1990 • 17 citations

Large fragments of nef‐protein and gp110 envelope glycoprotein from HIV‐1

1990 • 15 citations

In Vitro Characterization of a Biologically Active Molecular Clone of HIV-2_NIH-ZContaining anefDeletion and Expressing a Full-Length Transmembrane Protein

1990 • 6 citations

Inhibition of the In Vitro Generation of Class II-Restricted, HSV-1-Specific, CD4+ CTL by HIV-1

1990 • 4 citations

Deleted Work

1955 • 0 citations