Cellular Redistribution of Protein Tyrosine Phosphatases LAR and PTPσ by Inducible Proteolytic Processing

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1993 • 997 citations

Sublines of mouse 3T3 cells that accumulate lipid

1974 • 918 citations

Mammalian Membrane-bound Adenylyl Cyclases

1995 • 722 citations

MEMBRANE-ANCHORED GROWTH FACTORS

1993 • 676 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

1990 • 428 citations

1002 Protein Phosphatases?

1992 • 330 citations

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

1995 • 329 citations

Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo.

1995 • 313 citations

Calpain-catalyzed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets.

1993 • 309 citations

The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules

1993 • 291 citations

Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins

1991 • 287 citations

A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

1988 • 277 citations

Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

1986 • 275 citations

Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation

1993 • 268 citations

Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

1988 • 254 citations

Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex.

1996 • 251 citations

Soluble 80‐kd fragment of cell‐CAM 120/80 disrupts cell‐cell adhesion

1987 • 239 citations

Signal transduction by cell adhesion receptors

1995 • 239 citations

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase

1993 • 227 citations

Receptor tyrosine phosphatase R-PTP-kappa mediates homophilic binding.

1994 • 224 citations

Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.

1994 • 222 citations

Desmosomal cadherins: another growing multigene family of adhesion molecules

1994 • 199 citations

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

1995 • 199 citations

Association of Human Protein-tyrosine Phosphatase κ with Members of the Armadillo Family

1996 • 196 citations

Protein tyrosine phosphatases as adhesion receptors

1995 • 182 citations

Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium.

1991 • 173 citations

Expression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular region.

1992 • 166 citations

Cloning, expression and chromosomal localization of a new putative receptor‐like protein tyrosine phosphatase

1991 • 134 citations

Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase.

1991 • 132 citations

Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor.

1991 • 129 citations

Cloning and Characterization of R-PTP-κ, a New Member of the Receptor Protein Tyrosine Phosphatase Family with a Proteolytically Cleaved Cellular Adhesion Molecule-Like Extracellular Region

1993 • 128 citations

The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor

1992 • 126 citations

Cell surface expression of receptor protein tyrosine phosphatase RPTP mu is regulated by cell-cell contact.

1995 • 121 citations

Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu.

1994 • 112 citations

Purification and characterization of NCAD90, a Soluble endogenous form of N‐cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite‐promoting function

1993 • 108 citations

A novel receptor tyrosine phosphatase-sigma that is highly expressed in the nervous system.

1993 • 97 citations

Elevation of membrane tyrosine phosphatase activity in density-dependent growth-arrested fibroblasts.

1991 • 87 citations

Molecular Characterization of the Human Transmembrane Protein-tyrosine Phosphatase δ

1995 • 82 citations

LAR tyrosine phosphatase receptor: alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats.

1995 • 79 citations

The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype.

1988 • 75 citations

A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium

1993 • 75 citations

MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage.

1993 • 70 citations

Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression.

1993 • 68 citations

Mutational analysis of proprotein processing, subunit association, and shedding of the LAR transmembrane protein tyrosine phosphatase.

1994 • 68 citations

Rapid and Long Term Effects of Protein Kinase C on Receptor Tyrosine Kinase Phosphorylation and Degradation

1995 • 67 citations

Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development

1992 • 63 citations

The N-terminal and C-terminal domains of a receptor tyrosine phosphatase are associated by non-covalent linkage.

1992 • 61 citations

Activation of phosphotyrosine phosphatase activity by reduction of cell-substrate adhesion.

1993 • 58 citations

E‐Cadherin as an Invasion Suppressor

2007 • 53 citations

Genomic organization of the human LAR protein tyrosine phosphatase gene and alternative splicing in the extracellular fibronectin type-III domains.

1994 • 51 citations

Phorbol ester-induced scattering of HT-29 human intestinal cancer cells is associated with down-modulation of E-cadherin

1993 • 48 citations

Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family.

1996 • 46 citations

Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene.

1993 • 44 citations

Importance of tyrosine phosphatases in the effects of cell‐cell contact and microenvironments on EGF‐stimulated tyrosine phosphorylation

1992 • 43 citations

Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphatase family

1994 • 40 citations

Receptor tyrosine phosphatase R-PTP-κ mediates homophilic binding

1994 • 40 citations

Developmentally regulated expression of a murine receptor-type protein tyrosine phosphatase in the thymus.

1994 • 27 citations

Phorbol ester-induced activation of a membrane-bound candidate pro-transforming growth factor-alpha processing enzyme.

1994 • 23 citations

Orthovanadate both mimics and antagonizes the transforming growth factor β action on normal rat kidney cells

1993 • 20 citations

MPTPδ, a Putative Murine Homolog of HPTPδ, Is Expressed in Specialized Regions of the Brain and in the B-Cell Lineage

1993 • 20 citations

Expression of the tyrosine phosphatase LAR-PTP2 is developmentally regulated in lung epithelia

1994 • 17 citations

mRNA Expression of Two Transmembrane Protein Tyrosine Phosphatases Is Modulated by Growth Factors and Growth Arrest in 3T3 Fibroblasts

1995 • 16 citations