Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

Microglia: Intrinsic immuneffector cell of the brain

1995 • 1,099 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

1996 • 665 citations

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

1997 • 534 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA

1997 • 510 citations

Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II Expression

1996 • 356 citations

Dendritic Cells Induce Autoimmune Diabetes and Maintain Disease via De Novo Formation of Local Lymphoid Tissue

1998 • 315 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1998 • 307 citations

Class II transactivator regulates the expression of multiple genes involved in antigen presentation.

1995 • 267 citations

Critical Influences of the Cytokine Orchestration on the Outcome of Myelin Antigen‐Specific T‐Cell Autoimmunity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

1995 • 239 citations

The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system

1996 • 235 citations

Astrocyte-derived interleukin 3 as a growth factor for microglia cells and peritoneal macrophages.

1986 • 210 citations

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology.

1986 • 204 citations

Dendritic Cells Efficiently Induce Protective Antiviral Immunity

1998 • 189 citations

The Dendritic Cell System And Its Role In Immunogenicity

1991 • 174 citations

Quantitative control of MHC class II expression by the transactivator CIITA

1998 • 117 citations

Expression of Ia molecules by astrocytes during acute experimental allergic encephalomyelitis in the Lewis rat

1985 • 115 citations

Astrocytes Express Elements of the Class II Endocytic Pathway and Process Central Nervous System Autoantigen for Presentation to Encephalitogenic T Cells

1998 • 112 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 107 citations

IFN-gamma regulation of the type IV class II transactivator promoter in astrocytes.

1999 • 91 citations

Expression of Adhesion Molecules and Histocompatibility Antigens at the Blood‐Brain Barrier

1991 • 80 citations

CIITA activates the expression of MHC class II genes in mouse T cells

1995 • 75 citations

Cytokine expression by inflammatory cells obtained from the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis induced by inoculation with myelin basic protein and adjuvants

1998 • 29 citations

The role of cytokines in various animal models of inflammation.

1989 • 25 citations

Regulation by transforming growth factor-beta1 of class II mRNA and protein expression in fibroblast-like synoviocytes from patients with rheumatoid arthritis

1998 • 19 citations

IFN-gamma-induced MHC class II gene expression is suppressed in endothelial cells by dextran sulfate.

1996 • 19 citations

[Effects of interferon-gamma on the central nervous system].

2002 • 3 citations