Inhibition of autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

Apoptosis, oncosis, and necrosis. An overview of cell death.

1995 • 3,325 citations

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

1997 • 1,848 citations

Mitochondrial control of apoptosis

1997 • 1,500 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1982 • 1,313 citations

Studies on the mechanisms of autophagy: formation of the autophagic vacuole.

1990 • 789 citations

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.

1994 • 605 citations

Programmed cell death and Bcl-2 protection in the absence of a nucleus.

1994 • 560 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

Identification of Deoxyribonuclease II as an Endonuclease Involved in Apoptosis

1993 • 428 citations

[59] Inhibitors of lysosomal function

1983 • 331 citations

Ultrastructural and biochemical characterization of autophagy in higher plant cells subjected to carbon deprivation: control by the supply of mitochondria with respiratory substrates.

1996 • 270 citations

A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells.

1996 • 229 citations

The discovery of lysosomes.

1981 • 223 citations

Cell death: programmed, apoptosis, necrosis, or other?

1995 • 220 citations

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes.

1990 • 218 citations

Involvement of Cellular Proteolytic Machinery in Apoptosis

1997 • 184 citations

Toxin-induced cell lysis: Protection by 3-methyladenine and cycloheximide

1992 • 111 citations

Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats

1985 • 99 citations

Changes of Mitochondrial Mass in the Hemopoietic Stem Cell Line FDCP-Mix after Treatment with Etoposide: A Correlative Study by Multiparameter Flow Cytometry and Confocal and Electron Microscopy

1995 • 55 citations

TNF-mediated killing of human leukaemic cells: Effects of endogenous antioxidant levels and TNFα expression in leukaemic cell lines

1995 • 12 citations

Small virus‐like particles bud from the cell membranes of normal as well as HIV‐infected human lymphoid cells

1993 • 11 citations

DNA inclusions within autolytic cytoplasmic vacuoles of hemopoietic stem cell line FDCP-Mix.

1996 • 7 citations

Apoptosis Detection by DNA Analysis

2003 • 6 citations