Roles of metabotropic glutamate receptors in LTP and LTD in

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

Differential Presynaptic Localization of Metabotropic Glutamate Receptor Subtypes in the Rat Hippocampus

1997 • 1,105 citations

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1999 • 770 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

1997 • 631 citations

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

1994 • 607 citations

Long-Term Depression in Hippocampus

1996 • 583 citations

Two Distinct Forms of Long-Term Depression Coexist in CA1 Hippocampal Pyramidal Cells

1997 • 547 citations

Postsynaptic Induction and Presynaptic Expression of Hippocampal Long-Term Depression

1994 • 481 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation

1994 • 405 citations

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

1998 • 360 citations

Impairment of Hippocampal Mossy Fiber LTD in Mice Lacking mGluR2

1996 • 342 citations

The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus

1997 • 330 citations

(RS)-2-Chloro-5-Hydroxyphenylglycine (CHPG) Activates mGlu5, but not mGlu1, Receptors Expressed in CHO Cells and Potentiates NMDA Responses in the Hippocampus

1997 • 306 citations

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

1994 • 303 citations

Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus

1993 • 262 citations

Group 1 and 2 Metabotropic Glutamate Receptors Play Differential Roles in Hippocampal Long-Term Depression and Long-Term Potentiation in Freely Moving Rats

1997 • 235 citations

Selective Abolition of the NMDA Component of Long-Term Potentiation in Mice Lacking mGluR5

1998 • 229 citations

Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation

1995 • 197 citations

An investigation of depotentiation of longterm potentiation in the CA1 region of the hippocampus

1994 • 195 citations

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses

1995 • 175 citations

A Role for cAMP in Long-Term Depression at Hippocampal Mossy Fiber Synapses

1998 • 167 citations

The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity

1998 • 161 citations

Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors

1999 • 137 citations

Facilitation of long-term potentiation by prior activation of metabotropic glutamate receptors

1996 • 130 citations

Priming of long-term potentiation induced by activation of metabotropic glutamate receptors coupled to phospholipase C

1998 • 130 citations

Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus

1993 • 130 citations

When Are Class I Metabotropic Glutamate Receptors Necessary for Long-Term Potentiation?

1998 • 120 citations

Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning

1994 • 114 citations

Trans-ACPD enhances long-term potentiation in the hippocampus

1991 • 107 citations

Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro

1995 • 107 citations

Requirement of rapid Ca²⁺ entry and synaptic activation of metabotropic glutamate receptors for the induction of long‐term depression in adult rat hippocampus

1998 • 89 citations

Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats

1998 • 76 citations

Metabotropic Glutamate Receptor Mediated Long-term Depression in Developing Hippocampus

1997 • 76 citations

mGluR II agonist inhibition of LTP induction, and mGluR II antagonist inhibition of LTD induction, in the dentate gyrus in vitro

1997 • 70 citations

Evidence for Involvement of the cGMP–Protein Kinase G Signaling System in the Induction of Long-Term Depression, But Not Long-Term Potentiation, in the Dentate GyrusIn Vitro

1998 • 64 citations

Priming of group 2 metabotropic glutamate receptors facilitates induction of long-term depression in the dentate gyrus of freely moving rats

1998 • 60 citations

Evidence for Postsynaptic Induction and Expression of NMDA Receptor Independent LTP

1998 • 57 citations

Involvement of calcium/calmodulin-dependent protein kinases in the setting of a molecular switch involved in hippocampal LTP

1998 • 56 citations

On the mechanism of long-term potentiation induced by (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) in rat hippocampal slices

1995 • 54 citations

Metabotropic receptor stimulation coupled to weak tetanus leads to long-term potentiation and a rapid elevation of cytosolic protein kinase C activity

1993 • 54 citations

An antagonist of the metabotropic glutamate receptor prevents LTP in the dentate gyrus of freely moving rats

1993 • 54 citations

Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype

1997 • 49 citations

Two distinct forms of long-term depression coexist at the mossy fiber-CA3 synapse in the hippocampus during development

1998 • 47 citations

Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists

1995 • 46 citations

Group 1 metabotropic glutamate receptors contribute to slow-onset potentiation in the rat CA1 region in vivo

1997 • 42 citations

Regulation of synaptic plasticity by mGluR1 studied in vivo in mGluR1 mutant mice

1997 • 36 citations

Metabotropic Glutamate Receptors and Brain Function

1998 • 34 citations

Activation of group-II metabotropic glutamate receptors blocks induction of long-term potentiation and depotentiation in area CA1 of the rat in vivo

1997 • 32 citations

Antagonist activity of α‐substituted 4‐carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells

1999 • 31 citations

(+)-MCPG Blocks Induction of LTP in CA1 of Rat Hippocampus via Agonist Action at an mGluR Group II Receptor

1998 • 29 citations

A novel form of long‐term depression in the CA1 area of the adult rat hippocampus independent of glutamate receptors activation

1998 • 26 citations

(R,S)-α-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo

1997 • 25 citations

(RS)-α-Methyl-4-carboxyphenylglycine inhibits long-term potentiation only following the application of low frequency stimulation in the rat dentate gyrus in vitro

1995 • 21 citations

Potentiation of synaptic transmission in the rat dentate gyrus in vitro by (S)-3,5-dihydroxyphenylglycine ((S)-DHPG)

1997 • 20 citations

Metabotropic glutamate receptors are involved in calcium-induced LTP of AMPA and NMDA receptor-mediated responses in the rat hippocampus

1998 • 17 citations

Reduced long-term potentiation in the dentate gyrus of mGlu1 receptor-mutant mice in vivo

1996 • 17 citations

Priming of long-term potentiation by prior activation of group I and II metabotropic glutamate receptors in the rat dentate gyrus in vitro

1998 • 14 citations

The role of group II metabotropic glutamate receptors in hippocampal CA1 long-term potentiation in vitro

1998 • 11 citations

Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CAI synapses in the hippocampus

1999 • 8 citations

US report finds NIH's Gallo guilty of misstatement

1993 • 6 citations