(R,S)-α-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

A persistent postsynaptic modification mediates long-term potentiation in the hippocampus

1988 • 496 citations

NMDA application potentiates synaptic transmission in the hippocampus

1988 • 421 citations

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation

1994 • 405 citations

Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices

1991 • 356 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

The effects of repetitive low frequency stimulation on control and “potentiated” synaptic responses in the hippocampus

1980 • 315 citations

Stable depression of potentiated synaptic responses in the hippocampus with 1–5 Hz stimulation

1990 • 303 citations

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

1994 • 303 citations

Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases.

1994 • 281 citations

Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by d(−)aminophosphonovalerate

1987 • 269 citations

Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus

1993 • 262 citations

Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?

1990 • 259 citations

Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1

1996 • 230 citations

Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation

1995 • 197 citations

An investigation of depotentiation of longterm potentiation in the CA1 region of the hippocampus

1994 • 195 citations

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses

1995 • 175 citations

Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition

1991 • 168 citations

MCPG Antagonizes Metabotropic Glutamate Receptors but not Long‐term Potentiation in the Hippocampus

1994 • 166 citations

Factors regulating the reversibility of long-term potentiation

1996 • 158 citations

Reversal of LTP by theta frequency stimulation

1993 • 144 citations

Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat

1994 • 130 citations

Stimulation at 1-5 Hz does not produce long-term depression or depotentiation in the hippocampus of the adult rat in vivo

1995 • 117 citations

Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning

1994 • 114 citations

(RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons

1993 • 114 citations

A centrally active drug that modulates AMPA receptor gated currents

1994 • 111 citations

Trans-ACPD enhances long-term potentiation in the hippocampus

1991 • 107 citations

Co-activation of metabotropic glutamate and N-methyl-d-aspartate receptors is involved in mechanisms of long-term potentiation maintenance in rat hippocampal ca1 neurons

1993 • 106 citations

Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones

1995 • 101 citations

Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors

1994 • 95 citations

Metabotropic receptor-mediated long-term potentiation in rat hippocampal slices

1991 • 71 citations

Comparing the role of metabotropic glutamate receptors in long-term potentiation and in learning and memory

1996 • 67 citations

Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG

1995 • 67 citations

Thapsigargin blocks long-term potentiation induced by weak, but not strong tetanisation in rat hippocampal CA1 neurons

1995 • 62 citations

On the mechanism of long-term potentiation induced by (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) in rat hippocampal slices

1995 • 54 citations

The molecular switch hypothesis fails to explain the inconsistent effects of the metabotropic glutamate receptor antagonist MCPG on long-term potentiation

1995 • 42 citations

Studies on the role of metabotropic glutamate receptors in long-term potentiation: some methodological considerations

1995 • 39 citations

The effect of urethane anesthesia on evoked potentials in dentate gyrus

1995 • 38 citations

Effect of urethane on synaptic and amino acid-induced excitation in isolated spinal cord preparations

1982 • 37 citations

LTP in hippocampal CA1 of urethane-narcotized rats requires stronger tetanization parameters

1994 • 34 citations

1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo

1995 • 31 citations

(RS)-α-Methyl-4-carboxyphenylglycine (MCPG) does not block theta burst-induced long-term potentiation in area CA1 of rat hippocampal slices

1994 • 31 citations

Activation of metabotropic glutamate receptors induce differential effects on synaptic transmission in the dentate gyrus and CA1 of the hippocampus in the anaesthetized rat

1996 • 26 citations

Antagonists of the metabotropic glutamate receptor do not prevent induction of long-term potentiation in the dentate gyrus of rats

1995 • 26 citations

(RS)-α-Methyl-4-carboxyphenylglycine inhibits long-term potentiation only following the application of low frequency stimulation in the rat dentate gyrus in vitro

1995 • 21 citations

The Effects of <scp>l</scp>‐Glutamate and trans‐(±)‐1‐Amino‐1,3‐Cyclopentanedicarboxylate on Phosphoinositide Hydrolysis Can Be Pharmacologically Differentiated

1994 • 18 citations

Agonist action of (RS)-α-methyl-4-carboxyphenylglycine (MCPG) in the amygdala

1995 • 13 citations