Characterization of Mouse Atp6i Gene, the Gene Promoter, and the Gene Expression

Molecular cloning: A laboratory manual

1990 • 85,659 citations

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

1994 • 1,253 citations

Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency

1996 • 1,003 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

In situ Hybridization

1994 • 875 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts

1996 • 706 citations

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1

1997 • 531 citations

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification

1999 • 462 citations

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors.

1995 • 396 citations

Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone

1995 • 357 citations

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences

1996 • 351 citations

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

1994 • 340 citations

ON THE MECHANISMS OF BONE RESORPTION

1968 • 331 citations

Biology and Physiology of the Osteoclast

1992 • 297 citations

Isolated osteoclasts resorb the organic and inorganic components of bone.

1986 • 276 citations

Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution

1995 • 241 citations

Three Subunit a Isoforms of Mouse Vacuolar H+-ATPase

2000 • 232 citations

Autosomal Recessive Osteopetrosis: Variability of Findings at Diagnosis and During the Natural Course

1994 • 214 citations

BONE-MARROW TRANSPLANTATION FOR IMMUNODEFICIENCIES AND OSTEOPETROSIS: EUROPEAN SURVEY, 1968-1985

1986 • 201 citations

Human cathepsin S: chromosomal localization, gene structure, and tissue distribution

1994 • 193 citations

Inhibition of osteoclast proton transport by bafilomycin A1 abolishes bone resorption

1990 • 178 citations

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

1995 • 167 citations

Cathepsin K Antisense Oligodeoxynucleotide Inhibits Osteoclastic Bone Resorption

1997 • 155 citations

Expression of 92 kD type IV collagenase/gelatinase B in human osteoclasts

1994 • 140 citations

A nonsense mutation in the cathepsin K gene observed in a family with pycnodysostosis.

1996 • 133 citations

Molecular Cloning and Expression of Three Isoforms of the 100-kDa a Subunit of the Mouse Vacuolar Proton-translocating ATPase

2000 • 128 citations

New insights into the cellular, biochemical, and molecular basis of postmenopausal and senile osteoporosis: Roles of IL-6 and gp130

1995 • 117 citations

Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development

1996 • 114 citations

Differentiation kinetics of osteoclasts in the periosteum of embryonic bones in vivo and in vitro

1986 • 112 citations

Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas

1995 • 112 citations

Molecular Cloning and Characterization of a Putative Novel Human Osteoclast-Specific 116-kDa Vacuolar Proton Pump Subunit

1996 • 98 citations

In Situ Hybridization

1993 • 85 citations

Analysis of the 5′-Flanking Regions of Rat Inhibin α- and β-B-Subunit Genes Suggests Two Different Regulatory Mechanisms

1989 • 83 citations

Identification of two new exons and multiple transcription start points in the 5′-untranslated region of the human cathepsin-B-encoding gene

1995 • 79 citations

Isolation and reconstitution of a vacuolar-type proton pump of osteoclast membranes.

1994 • 76 citations

Cathepsin K: Isolation and Characterization of the Murine cDNA and Genomic Sequence, the Homologue of the Human Pycnodysostosis Gene

1996 • 65 citations

Structure and Chromosomal Assignment of the Human Cathepsin K Gene

1997 • 61 citations

Cathepsin K mRNA Detection Is Restricted to Osteoclasts During Fetal Mouse Development

1998 • 58 citations

Characterization of Mouse Cathepsin K Gene, the Gene Promoter, and the Gene Expression

1999 • 57 citations

Genomic Organization and Chromosome Localization of the Human Cathepsin K Gene (CTSK)

1997 • 51 citations

Cloning and characterization of the 5′-flanking region of the mouse tartrate-resistant acid phosphatase gene

1993 • 48 citations

Generation of Mouse Osteoclastogenic Cell Lines Immortalized with SV40 Large T Antigen

1998 • 38 citations

Properties of three isoforms of the 116‐kDa subunit of vacuolar H⁺‐ATPase from a single vertebrate species

2000 • 37 citations

Characterization of the 5′-flanking region of the human tartrate-resistant acid phosphatase (TRAP) gene

1995 • 19 citations

Characterization of a silencer element in the first exon of the human osteocalcin gene

1995 • 18 citations