Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

Bone and haematopoietic defects in mice lacking c-fos

1992 • 939 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1

1997 • 531 citations

Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence.

1982 • 379 citations

ON THE MECHANISMS OF BONE RESORPTION

1968 • 331 citations

Biology and Physiology of the Osteoclast

1992 • 297 citations

Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development

1997 • 292 citations

Autosomal Recessive Osteopetrosis: Variability of Findings at Diagnosis and During the Natural Course

1994 • 214 citations

Phagosome-lysosome fusion is a calcium-independent event in macrophages.

1996 • 115 citations

Molecular Cloning and Characterization of a Putative Novel Human Osteoclast-Specific 116-kDa Vacuolar Proton Pump Subunit

1996 • 98 citations

New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro

1993 • 93 citations

Effect of medium pH on osteoclast activity and osteoclast formation in cultures of dispersed rabbit osteoclasts

1993 • 82 citations

Characterization of Mouse Atp6i Gene, the Gene Promoter, and the Gene Expression

2001 • 67 citations

Characterization of Mouse Cathepsin K Gene, the Gene Promoter, and the Gene Expression

1999 • 57 citations

Generation of Mouse Osteoclastogenic Cell Lines Immortalized with SV40 Large T Antigen

1998 • 38 citations

The catalytic cycle of the vacuolar H(+)-ATPase. Comparison of proton transport in kidney- and osteoclast-derived vesicles.

1994 • 33 citations