Generation of Mouse Osteoclastogenic Cell Lines Immortalized with SV40 Large T Antigen

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

1994 • 1,253 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

1988 • 943 citations

Osteoclast-Like Cell Formation and its Regulation by Osteotropic Hormones in Mouse Bone Marrow Cultures*

1988 • 745 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

1997 • 735 citations

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1

1997 • 531 citations

The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells

1989 • 501 citations

Successful Bone-Marrow Transplantation for Infantile Malignant Osteopetrosis

1980 • 449 citations

The Effect of Calcium-Regulating Hormones and Prostaglandins on Bone Resorption by Osteoclasts Disaggregated from Neonatal Rabbit Bones*

1985 • 419 citations

Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone

1995 • 357 citations

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

1994 • 340 citations

In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes.

1982 • 333 citations

Immortalization of precursor cells from the mammalian CNS

1988 • 328 citations

1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow.

1985 • 280 citations

Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multinucleated osteoclasts.

1986 • 265 citations

Control of bone resorption by hematopoietic tissue. The induction and reversal of congenital osteopetrosis in mice through use of bone marrow and splenic transplants.

1975 • 248 citations

Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution

1995 • 241 citations

Identification of Committed Mononuclear Precursors for Osteoclast-Like Cells Formed in Long Term Human Marrow Cultures*

1990 • 232 citations

Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells.

1984 • 212 citations

Tumor suppressor genes

1994 • 206 citations

Generation of osteoclasts from isolated hematopoietic progenitor cells

1989 • 201 citations

A Comparative Study of Disaggregated Chick and Rat Osteoclasts in Vitro: Effects of Calcitonin and Prostaglandins*

1987 • 181 citations

Macrophages in T and B Cell Compartments and Other Tissue Macrophages Recognized by Monoclonal Antibody MOMA‐2

1987 • 173 citations

A Carboxyl-Terminal Peptide from the Parathyroid Hormone-Related Protein Inhibits Bone Resorption by Osteoclasts*

1991 • 168 citations

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

1995 • 167 citations

Preparation and characterization of a mouse osteoclast-like multinucleated cell population

1992 • 159 citations

Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse.

1993 • 148 citations

Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts

1986 • 131 citations

Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex.

1993 • 113 citations

Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas

1995 • 112 citations

A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth

1986 • 101 citations

Cell cycle targets of the DNA tumor viruses

1994 • 101 citations

New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro

1993 • 93 citations

Phorbol ester induced osteoclast-like differentiation of a novel human leukemic cell line (FLG 29.1).

1992 • 90 citations

Effect of medium pH on osteoclast activity and osteoclast formation in cultures of dispersed rabbit osteoclasts

1993 • 82 citations

TAF-like function of SV40 large T antigen.

1996 • 81 citations

Osteopetrosis in the ia rat cured by spleen cells from a normal littermate

1976 • 65 citations

Osteoclast formation from cloned pluripotent hemopoietic stem cells

1989 • 60 citations

The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex

1996 • 57 citations

Induction of Mononuclear Precursor Cells with Osteoclastic Phenotypes in a Rat Bone Marrow Culture System Depleted of Stromal Cells

1993 • 55 citations

Differentiation of HL-60 Cells into Cells with the Osteoclast Phenotype*

1991 • 53 citations

Human osteoclast and giant cell differentiation: the apparent switch from nonspecific esterase to tartrate resistant acid phosphatase activity coincides with the in situ expression of osteopontin mRNA.

1995 • 51 citations

Purification and characterization of fully functional human osteoclast precursors

1996 • 50 citations

Targeting simian virus 40 T antigen to the osteoclast in transgenic mice causes osteoclast tumors and transformation and apoptosis of osteoclasts.

1995 • 47 citations

Trypsinized osteoclast-like multinucleated cells formed in rat bone marrow cultures efficiently form resorption lacunae on dentine

1992 • 46 citations

Heat-treated osteoblastic cell (ROS17/2.8)-conditioned medium induces the formation of osteoclast-like cells

1993 • 45 citations

Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control

1996 • 43 citations

In vitro differentiation of the murine macrophage cell line BDM-1 into osteoclast-like cells.

1995 • 36 citations

Human fetal osteoclasts fail to express macrophage antigens.

1985 • 33 citations

The effects of stimulators of intracellular cyclic AMP on rat and chick osteoclasts in vitro: Validation of a simplified light microscope assay of bone resorption

1990 • 30 citations

A bone marrow fraction enriched for granulocyte-macrophage progenitors gives rise to osteoclasts in vitro

1988 • 27 citations

Interleukin-3-dependent hematopoietic stem cell lines capable of osteoclast formation in vitro

1991 • 25 citations

Characterization of a silencer element in the first exon of the human osteocalcin gene

1995 • 18 citations