Interplay between chromatin structure and transcription

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

1994 • 539 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

Histone Function in Transcription

1990 • 354 citations

The yeast cell-type-specific repressor α2 acts cooperatively with a non-cell-type-specific protein

1988 • 348 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array

1993 • 336 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome.

1988 • 316 citations

Origin Recognition Complex (ORC) in Transcriptional Silencing and DNA Replication in S. cerevisiae

1993 • 314 citations

Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.

1994 • 308 citations

Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast

1988 • 270 citations

The SNF/SWI family of global transcriptional activators

1994 • 269 citations

Chromatin Structure and Transcription

1992 • 259 citations

Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast.

1986 • 254 citations

Role of DNA replication in the repression of silent mating type loci in yeast

1984 • 254 citations

(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene.

1993 • 251 citations

A histone octamer can step around a transcribing polymerase without leaving the template

1994 • 238 citations

Silencers and Domains of Generalized Repression

1994 • 233 citations

A yeast protein that influences the chromatin structure of UASG and functions as a powerful auxiliary gene activator.

1990 • 229 citations

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast

1994 • 227 citations

Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast

1993 • 207 citations

Irresistible force meets immovable object: Transcription and the nucleosome

1991 • 175 citations

ATP-Dependent Nucleosome Reconfiguration and Transcriptional Activation from Preassembled Chromatin Templates

1994 • 163 citations

Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae.

1992 • 162 citations

TFIIF-TAF-RNA polymerase II connection.

1994 • 148 citations

A bacteriophage RNA polymerase transcribes in vitro through a nucleosome core without displacing it

1987 • 148 citations

Chromatin and gene expression: Constant questions, but changing answers

1994 • 130 citations

Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae

1992 • 121 citations

Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci.

1992 • 120 citations

In vitro replication through nucleosomes without histone displacement

1990 • 111 citations

Chromatin transitions during activation and repression of galactose-regulated genes in yeast.

1993 • 109 citations

GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo.

1993 • 109 citations

Nucleosome Disruption by Transcription Factor Binding in Yeast

1993 • 87 citations

Nucleosome positioning and gene regulation

1994 • 85 citations

Relation of Nucleosomes to DNA Sequences

1978 • 82 citations

On the displacement of histones from DNA by transcription

1988 • 75 citations

Transcriptional Activation: Switched-on chromatin

1994 • 60 citations

In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors.

1990 • 60 citations

Histones and the Regulation of Heterochromatin in Yeast

1993 • 53 citations

Octamer displacement and redistribution in transcription of single nucleosomes

1994 • 45 citations

New approaches to chromatin function.

1990 • 45 citations

36 Integration of Multiple Regulatory Inputs in the Control of HO Expression in Yeast

1992 • 29 citations