Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

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1994 • 4,698 citations

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1994 • 2,251 citations

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1988 • 2,203 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

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lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Interleukin-6 family of cytokines and gp130

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The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease

1993 • 848 citations

Local administration of antisense phosphorothiate olignucleotides to the p65 subunit of NF–κB abrogates established experimental colitis in mice

1996 • 839 citations

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 • 795 citations

Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop.

1993 • 600 citations

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1993 • 504 citations

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

1990 • 489 citations

Nuclear factor kappa B, a mediator of lipopolysaccharide effects

1993 • 476 citations

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1992 • 476 citations

Functional analysis of the human vascular cell adhesion molecule 1 promoter.

1992 • 442 citations

Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80.

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Isolation and functional characterization of human intestinal mucosal lymphoid cells.

1977 • 403 citations

Constitutive NF-kB Activity in Neurons

1994 • 400 citations

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1993 • 400 citations

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1993 • 369 citations

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1992 • 325 citations

The biological properties of interleukin-1.

1994 • 320 citations

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1994 • 304 citations

Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease.

1996 • 280 citations

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B.

1993 • 254 citations

A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.

1986 • 234 citations

Expression of leukocyte adhesion molecules by mucosal mononuclear phagocytes in inflammatory bowel disease

1991 • 197 citations

Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells

1993 • 196 citations

Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis.

1990 • 158 citations

Enhanced mucosal cytokine production in inflammatory bowel disease

1992 • 151 citations

Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent

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Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum.

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Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis

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The structure of the colonic mucosa. The epithelium and subepithelial reticulohistiocytic complex.

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1965 • 111 citations

NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.

1994 • 110 citations

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1993 • 108 citations

Selective Recognition of the Activated Form of Transcription Factor NF-χB by a Monoclonal Anfibody

1995 • 98 citations

Alterations of the phenotype of colonic macrophages in inflammatory bowel disease

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Interleukin 2 receptor expression by macrophages in inflammatory bowel disease.

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Immunology of inflammatory bowel disease

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An Evolutionary and Functional Approach to the TNF Receptor/Ligand Family

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Balance between pro- and antiinflammatory-cytokines in the colonic mucosa in inflammatory bowel diseases (IBD)

1995 • 7 citations