Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1989 • 1,269 citations

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.

1988 • 745 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Tumors secreting human TNF/cachectin induce cachexia in mice

1987 • 634 citations

Crohn's Disease (Regional Enteritis) of the Large Intestine and its Distinction from Ulcerative Colitis

1960 • 560 citations

Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease.

1989 • 430 citations

Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.

1987 • 372 citations

Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings

1989 • 365 citations

The role of cachectin/TNF in endotoxic shock and cachexia

1988 • 335 citations

Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor.

1988 • 300 citations

Intestinal lymphocyte subpopulations in inflammatory bowel disease: an analysis by immunohistological and cell isolation techniques.

1984 • 273 citations

Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease.

1983 • 264 citations

In vivo profiles of eicosanoids in ulcerative colitis, Crohn's colitis, and Clostridium difficile colitis

1988 • 185 citations

Methane excretion in man--a study of breath, flatus, and faeces.

1985 • 184 citations

Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis.

1990 • 158 citations

Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum.

1989 • 140 citations

Heterogeneity of HLA-DR-positive histiocytes in human intestinal lamina propria: a combined histochemical and immunohistological analysis.

1983 • 130 citations

Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease.

1983 • 118 citations

The Pathology of Regional Enteritis

1951 • 117 citations

Histological diagnosis of chronic inflammatory bowel disease in childhood.

1985 • 111 citations

Macrophage heterogeneity in normal colonic mucosa and in inflammatory bowel disease.

1988 • 107 citations

Food Allergy and Intolerance

1987 • 93 citations

Altered patterns of secretion of monomeric IgA and IgA subclass 1 by intestinal mononuclear cells in inflammatory bowel disease

1986 • 92 citations

Crohn's disease in childhood.

1977 • 87 citations

Dendritic cells and scavenger macrophages in chronic inflammatory bowel disease.

1989 • 87 citations

Immunoregulatory Function of Lamina Propria T Cells in Crohn's Disease

1985 • 74 citations

Interleukin 2 receptor expression by macrophages in inflammatory bowel disease.

1988 • 70 citations

The detection and enumeration of cytokine-secreting cells in mice and man and the clinical application of these assays

1989 • 64 citations

HLA-DR expression in human fetal intestinal epithelium.

1988 • 60 citations

Immunoregulatory function of human intestinal mucosa lymphoid cells: evidence for enhanced suppressor cell activity in inflammatory bowel disease.

1983 • 55 citations

T cell-B cell regulation in the intestinal lamina propria in Crohn's disease

1985 • 45 citations

Selective biopsy of human Peyer's patches during ileal endoscopy

1987 • 42 citations

Expression of HLA-DR antigens in inflammatory bowel disease mucosa: Role of intestinal lamina propria mononuclear cell-derived interferon ?

1988 • 41 citations

Differential secretion of tumor necrosis factor‐α and granulocyte/macrophage colony‐stimulating factors but not interferon‐γ from CD4 compared to CD8 human T cell clones

1989 • 27 citations

Regional enteritis in childhood

1972 • 13 citations