Current best treatment for non-alcoholic fatty liver disease

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

2002 • 18,132 citations

Nonalcoholic Fatty Liver Disease

2002 • 5,091 citations

Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆

1999 • 3,339 citations

Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis

1999 • 1,610 citations

The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years

1990 • 1,475 citations

Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma

2002 • 1,445 citations

Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease

1999 • 1,148 citations

Nonalcoholic steatohepatitis: An expanded clinical entity

1994 • 1,113 citations

Liver fibrosis in overweight patients

2000 • 966 citations

Executive Summary of the Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults

1998 • 912 citations

The natural history of nonalcoholic fatty liver: A follow-up study

1995 • 898 citations

Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

2003 • 893 citations

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

1997 • 815 citations

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

2000 • 746 citations

AHA Dietary Guidelines

2000 • 683 citations

Metformin reverses fatty liver disease in obese, leptin-deficient mice

2000 • 680 citations

Therapeutic effects of restricted diet and exercise in obese patients with fatty liver

1997 • 624 citations

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1998 • 611 citations

Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: A pilot study

1996 • 564 citations

Nonalcoholic steatohepatitis: A study of 49 patients

1989 • 555 citations

Vitamin E treatment of nonalcoholic steatohepatitis in children: A pilot study

2000 • 532 citations

Alcohollike liver disease in nonalcoholics

1988 • 485 citations

Alterations in Liver ATP Homeostasis in Human Nonalcoholic Steatohepatitis

1999 • 481 citations

Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis

2002 • 471 citations

Obesity Induces Expression of Uncoupling Protein-2 in Hepatocytes and Promotes Liver ATP Depletion

1999 • 442 citations

Thiazolidinediones: a new class of antidiabetic drugs

1999 • 429 citations

Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study

2001 • 428 citations

Nonalcoholic Steatohepatitis in Children

2000 • 420 citations

Plasma transforming growth factor‐β1 level and efficacy of α‐tocopherol in patients with non‐alcoholic steatohepatitis: a pilot study

2001 • 415 citations

Hepatic effects of dietary weight loss in morbidly obese subjects

1991 • 415 citations

Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis

2001 • 399 citations

A Pilot Study of A Thiazolidinedione, Troglitazone, in Nonalcoholic Steatohepatitis

2001 • 392 citations

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

1996 • 391 citations

Liver involvement in obese children. Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population.

1997 • 384 citations

Effect of weight reduction on hepatic abnormalities in overweight patients

1990 • 381 citations

Fatty infiltration of liver in hyperlipidemic patients.

2000 • 347 citations

Choline deficiency: A cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation

1995 • 314 citations

Effect on Hepatic Morphology of Treatment of Obesity by Fasting, Reducing Diets and Small-Bowel Bypass

1970 • 297 citations

Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice

1996 • 277 citations

Frequency of nonalcoholic steatohepatitis as a cause of advanced liver disease

2001 • 266 citations

Hepatic Steatosis After Intestinal Bypass—Prevention and Reversal by Metronidazole, Irrespective of Protein-Calorie Malnutrition

1982 • 233 citations

Effect of iron depletion in carbohydrate-intolerant patients with clinical evidence of nonalcoholic fatty liver disease

2002 • 230 citations

A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C

1997 • 224 citations

Persistent hyperaminotransferasemia resolving after weight reduction in obese children

1994 • 202 citations

Nonalcoholic Steatohepatitis in Obesity: A Reversible Condition

1986 • 201 citations

Dietary Betaine Promotes Generation of Hepatic S‐Adenosylmethionine and Protects the Liver from Ethanol‐Induced Fatty Infiltration

1993 • 178 citations

Liver morphology and function tests in obesity and during total starvation

1967 • 147 citations

Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients

1992 • 145 citations

Lack of efficacy of ursodeoxycholic acid for the treatment of liver abnormalities in obese children

2000 • 135 citations

Treatment of Nonalcoholic Fatty Liver: Present and Emerging Therapies

2001 • 127 citations

Intestinal Bypass Surgery for Morbid Obesity: Long-Term Results

2014 • 120 citations

Polymyxin B reduces cecal flora, TNF production and hepatic steatosis during total parenteral nutrition in the rat

1991 • 112 citations

Use of ursodeoxycholic acid in patients with liver disease

2002 • 76 citations

A possible beneficial effect of metronidazole in reducing TPN-associated liver function derangements

1985 • 74 citations

Jejunoileal Bypass as a Treatment of Morbid Obesity

1977 • 69 citations

Treatment of non-alcoholic steatohepatitis

2002 • 69 citations

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2001 • 66 citations

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2000 • 66 citations

Atorvastatin for the treatment of NASH

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Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients

1992 • 52 citations

Pharmacological Approaches for the Treatment of Obesity

2002 • 43 citations

Steatosis and Collagen Content in Experimental Liver Cirrhosis Are Affected by Dietary Monounsaturated and Polyunsaturated Fatty Acids

1997 • 28 citations

Phlebotomy reduces transaminase levels in patients with non-alcholic steatohepatitis

2000 • 15 citations

Serum markers of liver fibrosis in patients with Non-Alcoholic Steatohepatitis (NASH). Correlation to liver morphology and effect of therapy

2000 • 10 citations