Insulin resistance and mitochondrial abnormalities in NASH: A cool look into a burning issue

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Nonalcoholic Steatohepatitis Mayo Clinic Experiences With a Hitherto Unnamed Disease

1980 • 2,667 citations

Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities

2001 • 2,021 citations

Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis

1999 • 1,610 citations

Association of nonalcoholic fatty liver disease with insulin resistance

1999 • 1,560 citations

The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years

1990 • 1,475 citations

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.

1995 • 1,316 citations

The natural history of nonalcoholic fatty liver: A follow-up study

1995 • 898 citations

Nonalcoholic fatty liver disease

2002 • 894 citations

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

2000 • 746 citations

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1998 • 611 citations

Liver Pathology and the Metabolic Syndrome X in Severe Obesity

1999 • 592 citations

Mitochondrial abnormalities in non-alcoholic steatohepatitis

1999 • 494 citations

Alcohollike liver disease in nonalcoholics

1988 • 485 citations

Alterations in Liver ATP Homeostasis in Human Nonalcoholic Steatohepatitis

1999 • 481 citations

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

1996 • 391 citations

Mitochondrial Adaptations to Obesity-Related Oxidant Stress

2000 • 362 citations

Age as Independent Determinant of Glucose Tolerance

1991 • 259 citations

Comparison of serum concentrations of α-tocopherol and β-carotene in a cross-sectional sample of obese and nonobese children (NHANES III)

1999 • 200 citations

Nonalcoholic fatty liver disease

2020 • 184 citations

Transdifferentiation of Rat Hepatic Stellate Cells Results in Leptin Expression

1998 • 181 citations

Evidence for mitochondrial DNA damage by lipid peroxidation

1988 • 160 citations

Liver steatosis in juvenile obesity: correlations with lipid profile, hepatic biochemical parameters and glycemic and insulinemic responses to an oral glucose tolerance test

2000 • 157 citations

Inhibition of cytochrome c oxidase activity by 4-hydroxynonenal (HNE)

1998 • 147 citations

Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes

1997 • 94 citations

Effect of leptin on cytochrome P-450, conjugation, and antioxidant enzymes in the ob/ob mouse.

1999 • 78 citations

Role of Hyperinsulinemia and Glucose Intolerance in the Pathogenesis of Nonalcoholic Fatty Liver in Patients with Normal Body Weight

1998 • 51 citations

Glutathione depletion by hyperphagia-induced obesity

1989 • 37 citations

Abnormal antioxidant defence in some tissues of congenitally obese mice

1984 • 33 citations

Leptin and TNF alpha levels in hepatitis C and its relationship withhepatic fibrosis

2000 • 1 citations