Control of muscle development by dueling HATs and HDACs

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

TRANSCRIPTIONAL CONTROL OF MUSCLE DEVELOPMENT BY MYOCYTE ENHANCER FACTOR-2 (MEF2) PROTEINS

1998 • 1,026 citations

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

2000 • 1,024 citations

Control of Mouse Cardiac Morphogenesis and Myogenesis by Transcription Factor MEF2C

1997 • 1,024 citations

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

1998 • 984 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1997 • 770 citations

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 • 744 citations

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3- 3-dependent cellular localization

2000 • 595 citations

The Human Histone Deacetylase Family

2001 • 541 citations

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

1999 • 539 citations

Regulation of Skeletal Myogenesis by Association of the MEF2 Transcription Factor with Class II Histone Deacetylases

2000 • 537 citations

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

2000 • 511 citations

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

2000 • 504 citations

MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type

2000 • 455 citations

p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation

1999 • 444 citations

Regulation of the MEF2 Family of Transcription Factors by p38

1999 • 429 citations

Differential Roles of p300 and PCAF Acetyltransferases in Muscle Differentiation

1997 • 419 citations

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

2000 • 409 citations

Regulation of Histone Acetyltransferases p300 and PCAF by the bHLH Protein Twist and Adenoviral Oncoprotein E1A

1999 • 372 citations

Molecular Mechanisms of Myogenic Coactivation by p300: Direct Interaction with the Activation Domain of MyoD and with the MADS Box of MEF2C

1997 • 363 citations

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.

1996 • 361 citations

Acetylation of MyoD Directed by PCAF Is Necessary for the Execution of the Muscle Program

1999 • 351 citations

A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity

1999 • 343 citations

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation

2001 • 325 citations

Human p300 Protein Is a Coactivator for the Transcription Factor MyoD

1996 • 319 citations

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

2000 • 317 citations

Muscle differentiation: more complexity to the network of myogenic regulators

1998 • 286 citations

Identification of a Signal-Responsive Nuclear Export Sequence in Class II Histone Deacetylases

2001 • 284 citations

p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

1997 • 281 citations

HDAC4, a Human Histone Deacetylase Related to Yeast HDA1, Is a Transcriptional Corepressor

1999 • 280 citations

Regulation of Histone Deacetylase 4 by Binding of 14-3-3 Proteins

2000 • 271 citations

Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis.

1997 • 259 citations

Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development

2000 • 252 citations

A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

2001 • 250 citations

Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors

1999 • 250 citations

Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis

2000 • 219 citations

Association of COOH-terminal-binding Protein (CtBP) and MEF2-interacting Transcription Repressor (MITR) Contributes to Transcriptional Repression of the MEF2 Transcription Factor

2001 • 210 citations

mHDA1/HDAC5 Histone Deacetylase Interacts with and Represses MEF2A Transcriptional Activity

2000 • 203 citations

A Dynamic Role for HDAC7 in MEF2-mediated Muscle Differentiation

2001 • 201 citations

MEF-2 function is modified by a novel co-repressor, MITR

1999 • 194 citations

The SMRT Corepressor Is Regulated by a MEK-1 Kinase Pathway: Inhibition of Corepressor Function Is Associated with SMRT Phosphorylation and Nuclear Export

2000 • 187 citations

The Insulin-like Growth Factor-Phosphatidylinositol 3-Kinase-Akt Signaling Pathway Regulates Myogenin Expression in Normal Myogenic Cells but Not in Rhabdomyosarcoma-derived RD Cells

2000 • 182 citations

Cabin1 Represses MEF2-Dependent Nur77 Expression and T Cell Apoptosis by Controlling Association of Histone Deacetylases and Acetylases with MEF2

2000 • 156 citations

The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation

2000 • 142 citations

CREB-binding Protein/p300 Activates MyoD by Acetylation

2000 • 125 citations

A Novel Rb- and p300-Binding Protein Inhibits Transactivation by MyoD

2000 • 123 citations

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

2000 • 120 citations

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5

2000 • 119 citations

The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis

2001 • 115 citations

Crystal structure of MEF2A core bound to DNA at 1.5 Å resolution

2000 • 114 citations

The Nuclear Receptor Corepressor N-CoR Regulates Differentiation: N-CoR Directly Interacts with MyoD

1999 • 74 citations

Control of Cardiac-specific Transcription by p300 through Myocyte Enhancer Factor-2D

2001 • 72 citations

Ability of adenovirus 5 E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300 kDa cellular protein.

1992 • 68 citations

SMRTe Inhibits MEF2C Transcriptional Activation by Targeting HDAC4 and 5 to Nuclear Domains

2001 • 60 citations

The Nuclear Receptor Corepressor N-CoR Regulates Differentiation: N-CoR Directly Interacts with MyoD

1999 • 17 citations

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