Cloning and Deletion Mutagenesis of the α2δ Calcium Channel Subunit from Porcine Cerebral Cortex

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

Arzneimittelforschung

2005 • 8,820 citations

The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel

1996 • 1,164 citations

STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS

1995 • 941 citations

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 • 922 citations

Primary structure and functional expression from complementary DNA of a brain calcium channel

1991 • 871 citations

‘Zinc fingers’: a novel protein motif for nucleic acid recognition

1987 • 676 citations

Sequence and Expression of mRNAs Encoding the α ₁ and α ₂ Subunits of a DHP-Sensitive Calcium Channel

1988 • 579 citations

The Roles of the Subunits in the Function of the Calcium Channel

1991 • 550 citations

Structure and functional expression of α1, α2, and β subunits of a novel human neuronal calcium channel subtype

1992 • 499 citations

The naming of voltage-gated calcium channels

1994 • 360 citations

The complete mitochondrial DNA sequence of the horse, Equus caballus: extensive heteroplasmy of the control region

1994 • 309 citations

Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution‐state structure of the nucleocapsid protein from HIV‐1

1992 • 291 citations

Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene.

1990 • 288 citations

The effect of gabapentin on brain gamma‐aminobutyric acid in patients with epilepsy

1996 • 286 citations

Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides.

1991 • 260 citations

The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed byd-serine

1996 • 234 citations

Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies

1993 • 227 citations

Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain

1991 • 191 citations

Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons

1993 • 174 citations

Primary structure of the low molecular weight nucleic acid-binding proteins of murine leukemia viruses.

1981 • 153 citations

Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin

1993 • 145 citations

Importance of the Different |β Subunits in the Membrane Expression of the α1A and α2 Calcium Channel Subunits: Studies Using a Depolarization‐sensitive α1A Antibody

1997 • 145 citations

The Hansenula polymorpha PER8 gene encodes a novel peroxisomal integral membrane protein involved in proliferation.

1995 • 134 citations

Calcium channels: Structure, function, and classification

1994 • 121 citations

Spinal gabapentin is antinociceptive in the rat formalin test

1997 • 116 citations

Gabapentin as a novel treatment for postherpetic neuralgia

1996 • 114 citations

Rat brain expresses an alternatively spliced form of the dihydropyridine-sensitive L-type calcium channel alpha 2 subunit.

1992 • 114 citations

Antiepileptic Drug Mechanisms of Action

1993 • 110 citations

Perspectives on zinc finger protein function and evolution - an update

1994 • 103 citations

Human neuronal voltage-dependent calcium channels: Studies on subunit structure and role in channel assembly

1993 • 99 citations

Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: Are there common or different sites of action?

1983 • 97 citations

Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro

1995 • 86 citations

Effects of gabapentin on release of gamma-aminobutyric acid from slices of rat neostriatum.

1993 • 80 citations

Isolation of the [3H]Gabapentin-Binding Protein/α2δ Ca2+Channel Subunit from Porcine Brain: Development of a Radioligand Binding Assay for α2δ Subunits Using [3H]Leucine

1998 • 77 citations

Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.

1991 • 71 citations

[3H]Gabapentin may label a system-L-like neutral amino acid carrier in brain

1993 • 65 citations

The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis

1995 • 60 citations

The α2/δ subunit of voltage sensitive Ca²⁺ channels is a single transmembrane extracellular protein which is involved in regulated secretion

1996 • 60 citations

Use of site‐directed antibodies to probe the topography of theα₂ subunit of voltage‐gated Ca²⁺ channels

1995 • 51 citations

Clustering of the acetylcholine receptor by the 43-kD protein: involvement of the zinc finger domain.

1993 • 45 citations

Native‐type DHP‐sensitive calcium channel currents are produced by cloned rat aortic smooth muscle and cardiac α₁ subunits expressed in Xenopus laevis ooeytes and are regulated by α₂‐ and β‐subunits

1992 • 43 citations

Spermine modulation of specific [³H]‐gabapentin binding to the detergent‐solubilized porcine cerebral cortex α₂δ calcium channel subunit

1997 • 29 citations

Gabapentin for the Treatment of Hemifacial Spasm

1996 • 25 citations

The large glycoprotein subunit of the skeletal muscle voltage‐sensitive calcium channel

1988 • 23 citations

INTRODUCTION

1994 • 1 citations

Alzheimer's disease—a guide for carers

2005 • 1 citations