Perspectives on zinc finger protein function and evolution - an update

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Cloning of the zebrafishkrox-20gene (krx-20) and its expression during hindbrain development

1993 • 708 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

1993 • 679 citations

Binding of the Wilms' Tumor Locus Zinc Finger Protein to the EGR-1 Consensus Sequence

1990 • 588 citations

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo

1993 • 582 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

1991 • 549 citations

Developmental Expression of Sp1 in the Mouse

1991 • 533 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.

1980 • 511 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

Transcriptional Repression Mediated by the WT1 Wilms Tumor Gene Product

1991 • 492 citations

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.

1990 • 478 citations

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

1993 • 469 citations

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins.

1993 • 464 citations

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

1993 • 452 citations

A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

1988 • 428 citations

Zinc Finger Phage: Affinity Selection of Fingers with New DNA-Binding Specificities

1994 • 417 citations

The GLI gene is a member of the Kruppel family of zinc finger proteins

1988 • 396 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

1991 • 368 citations

Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene.

1992 • 354 citations

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition

1993 • 347 citations

The GLI-Kruppel family of human genes.

1988 • 302 citations

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.

1988 • 301 citations

The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

1993 • 297 citations

The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects.

1993 • 280 citations

Developmental expression of Sp1 in the mouse.

1991 • 276 citations

Base sequence discrimination by zinc-finger DNA-binding domains

1991 • 261 citations

Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila.

1990 • 246 citations

Isolation of a 7S particle from Xenopus laevis oocytes: a 5S RNA-protein complex.

1979 • 244 citations

Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.

1991 • 243 citations

Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation

1980 • 233 citations

Molecular analysis of the C. elegans sex-determining gene tra-1: A gene encoding two zinc finger proteins

1992 • 233 citations

Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins.

1993 • 227 citations

Toward rules relating zinc finger protein sequences and DNA binding site preferences.

1992 • 223 citations

Modulation of DNA Binding Specificity by Alternative Splicing of the Wilms Tumor wt1 Gene Transcript

1992 • 221 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

Protein-mediated nuclear export of RNA: 5S rRNA containing small RNPs in xenopus oocytes

1990 • 205 citations

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.

1991 • 201 citations

The Drosophila su(Hw) gene, which controls the phenotypic effect of the gypsy transposable element, encodes a putative DNA-binding protein.

1988 • 184 citations

RNA and DNA binding zinc fingers in Xenopus TFIIIA

1992 • 169 citations

A Drosophila homologue of human Sp1 is a head-specific segmentation gene

1993 • 166 citations

odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos.

1994 • 165 citations

Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt)

1992 • 164 citations

Determination of the base recognition positions of zinc fingers from sequence analysis.

1992 • 140 citations

The genomic organization and expression of the WT1 gene

1992 • 140 citations

The GLI Gene Encodes a Nuclear Protein Which Binds Specific Sequences in the Human Genome

1990 • 131 citations

Molecular Basis for Specific Recognition of Both RNA and DNA by a Zinc Finger Protein

1993 • 131 citations

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

1993 • 130 citations

Transcriptional repressor ZF5 identifies a new conserved domain in zina finger proteins

1993 • 120 citations

Cloning of GT Box-Binding Proteins: A Novel Spl Multigene Family Regulating T-Cell Receptor Gene Expression

1992 • 114 citations

Structure of tbe gene forXenopustranscription factor TMIIIA

1986 • 108 citations

Wilms' tumour: reconciling genetics and biology

1992 • 107 citations

Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury.

1993 • 96 citations

A Novel, Tissue-Restricted Zinc Finger Protein (HF-1b) Binds to the Cardiac Regulatory Element (HF-1b/MEF-2) in the Rat Myosin Light-Chain 2 Gene

1993 • 85 citations

Evolutionary conserved modules associated with zinc fingers in Xenopus laevis.

1989 • 85 citations

Molecular cloning of rat Wilms' tumor complementary DNA and a study of messenger RNA expression in the urogenital system and the brain.

1992 • 81 citations

The GLI-Kruppel Family of Human Genes

1988 • 78 citations

Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction

1991 • 65 citations

Expression of a Zinc Finger Gene in HTLV-I- and HTLV-II-Transformed Cells

1990 • 62 citations

Mutations in 5S DNA and 5S RNA have different effects on the binding of Xenopus transcription factor IIIA

1991 • 58 citations

Isolation, Characterization, and Expression of the Murine Wilms’ Tumor Gene (WT1) During Kidney Development

1991 • 57 citations

The Early Response Gene NGFI-C Encodes a Zinc Finger Transcriptional Activator and Is a Member of the GCGGGGGCG (GSG) Element-Binding Protein Family

1991 • 54 citations

cDNA sequence of the human cellular early growth response gene Egr-1

1990 • 51 citations

A novel, tissue-restricted zinc finger protein (HF-1b) binds to the cardiac regulatory element (HF-1b/MEF-2) in the rat myosin light-chain 2 gene.

1993 • 48 citations

Clone pAT 133 identifies a gene that encodes another human member of a class of growth factor-induced genes with almost identical zinc-finger domains.

1991 • 41 citations

The FAR domain defines a new Xenopus laevis zinc finger protein subfamily with specific RNA homopolymer binding activity

1994 • 31 citations

Isolation and sequence of a rat glucose-6-phosphate dehydrogenase promoter

1994 • 26 citations

Evidence for a Clustered Genomic Organization of FAX-Zinc Finger Protein Encoding Transcription Units in Xenopus laevis

1993 • 18 citations

Kid-1, a Putative Renal Transcription Factor: Regulation during Ontogeny and in Response to Ischemia and Toxic Injury

1993 • 14 citations