CD4+ T cell responses in mice lacking MHC class II molecules specifically on B cells

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

Mice lacking MHC class II molecules

1991 • 869 citations

Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

1996 • 665 citations

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

1996 • 581 citations

B220: a B cell-specific member of the T200 glycoprotein family

1981 • 525 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Cytoplasmic Domain Heterogeneity and Functions of IgG Fc Receptors in B Lymphocytes

1992 • 462 citations

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors.

1984 • 422 citations

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the J_H locus

1993 • 404 citations

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1998 • 380 citations

Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.

1984 • 351 citations

B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo.

1995 • 303 citations

B Lymphocytes Induce the Formation of Follicular Dendritic Cell Clusters in a Lymphotoxin α–dependent Fashion

1998 • 296 citations

T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes.

1987 • 286 citations

H-2 Dependence of Co-Operation Between T and B Cells in Vivo

1972 • 285 citations

Successful T cell priming in B cell-deficient mice.

1995 • 284 citations

Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex

1975 • 276 citations

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

1997 • 257 citations

The B cell is the initiating antigen-presenting cell in peripheral lymph nodes.

1987 • 240 citations

Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies.

1991 • 212 citations

B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes.

1993 • 210 citations

Compartmentalization of MHC class II gene expression in transgenic mice

1988 • 201 citations

The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice.

1988 • 199 citations

Can B cells turn on virgin T cells?

1988 • 192 citations

Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex.

1978 • 185 citations

Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation.

1984 • 182 citations

Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgG

1992 • 173 citations

CD8 T cell memory in B cell-deficient mice.

1996 • 158 citations

Cutaneous leishmaniasis in anti-IgM-treated mice: enhanced resistance due to functional depletion of a B cell-dependent T cell involved in the suppressor pathway.

1984 • 153 citations

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

1996 • 149 citations

Antigen presentation by splenic B cells: resting B cells are ineffective, whereas activated B cells are effective accessory cells for T cell responses.

1985 • 145 citations

Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice

1997 • 133 citations

Gene-targeted B-deficient mice reveal a critical role for B cells in the CD4 T cell response

1995 • 109 citations

CD4+ T cell activation and tolerance induction in B cell knockout mice.

1996 • 103 citations

Long-lasting CD8 T cell memory in the absence of CD4 T cells or B cells.

1996 • 101 citations

Defective induction of antigen‐reactive proliferating T cells in B cell‐deprived mice

1981 • 99 citations

Absence of an antigen‐specific helper T cell required for the expression of the Tn 15 idiotype in mice treated with anti‐μ antibody

1980 • 92 citations

T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.

1986 • 88 citations

T cells discriminate between Ia antigens expressed on allogeneic accessory cells and B cells: a potential function for carbohydrate side chains on Ia molecules.

1983 • 86 citations

Antigen-Primed T Cells from B Cell-Deficient JHD Mice Fail to Provide B Cell Help

1998 • 83 citations

B cells are not essential for peripheral T-cell tolerance.

1996 • 65 citations

Altered response of CD4⁺ T cell subsets to Plasmodium chabaudi chabaudi in B cell-deficient mice

1993 • 62 citations

The role of the B cells in the adoptive transfer of collagen‐induced arthritis from DBA/1 (H‐2^q) to SCID (H−2^d) mice

1995 • 57 citations

Capacity of small B cell‐enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C‐treated stimulators

1985 • 51 citations

Role of B-cell and Fc receptors in the selection of T-cell epitopes

1998 • 48 citations

Strong priming of T cells adoptively transferred into scid mice.

1991 • 42 citations

Co-transfer of B cells converts resistance into susceptibility in T cell-reconstituted, Leishmania major-resistant C.B-17 scid mice by a non-congnate mechanism

1996 • 30 citations

Antigen‐specific B cells are required for the secondary response of T cells but not for their priming

1996 • 18 citations

Bacterial superantigens induce T cell unresponsiveness in B cell‐deficient mice

1995 • 12 citations