CD8 T cell memory in B cell-deficient mice.

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

How B and T cells talk to each other

1994 • 659 citations

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

1990 • 558 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Immune function in mice lacking the perforin gene.

1994 • 474 citations

The Follicular Dendritic Cell: Long Term Antigen Retention During Immunity

1980 • 377 citations

T cell memory is short-lived in the absence of antigen.

1991 • 367 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release.

1984 • 346 citations

Regulation of apoptosis in the immune system

1994 • 321 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo

1984 • 296 citations

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction

1978 • 296 citations

T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes.

1987 • 286 citations

T and B memory cells

1994 • 285 citations

Successful T cell priming in B cell-deficient mice.

1995 • 284 citations

Immunological Memory

1993 • 250 citations

The B cell is the initiating antigen-presenting cell in peripheral lymph nodes.

1987 • 240 citations

Lipopolysaccharide interferes with the induction of peripheral T cell death

1995 • 240 citations

Human cytotoxic T-cell memory: long-lived responses to vaccinia virus

1996 • 216 citations

B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes.

1993 • 210 citations

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

1992 • 204 citations

Antigens, Lymphoid Cells and the Immune Response

1971 • 200 citations

The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice.

1988 • 199 citations

The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen.

1994 • 190 citations

Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response

1987 • 185 citations

Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus

1993 • 185 citations

Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation.

1984 • 182 citations

A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge

1993 • 176 citations

Antigen presentation to cytotoxic T lymphocytes in vivo.

1995 • 168 citations

Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion.

1995 • 168 citations

Fine dissection of a nine amino acid glycoprotein epitope, a major determinant recognized by lymphocytic choriomeningitis virus-specific class I-restricted H-2Db cytotoxic T lymphocytes.

1988 • 166 citations

Immunological Memory

1993 • 166 citations

On the cellular basis of immunological T cell memory

1995 • 159 citations

Hepatitis B virus immunopathology

1995 • 142 citations

T cell memory. Long-term persistence of virus-specific cytotoxic T cells.

1989 • 109 citations

T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.

1986 • 88 citations

Immune therapy of a persistent and disseminated viral infection

1987 • 77 citations

Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells

1987 • 76 citations

Strong priming of T cells adoptively transferred into scid mice.

1991 • 42 citations

T cell development in B cell-deficient mice. II. Serological characterization of suppressor T cell factors (TsF1) produced in normal mice and in mice treated chronically with rabbit anti-mouse IgM antibodies.

1985 • 37 citations

Cellular immunity to intracellular bacteria

1993 • 34 citations

Numbers of cytolytic T lymphocytes (CTL) and CTL precursor cells in spleens of mice acutely infected with lymphocytic choriomeningitis virus

1986 • 14 citations