p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

1995 • 733 citations

Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation

1995 • 639 citations

Regulation of Human Leukocyte p21-Activated Kinases Through G Protein—Coupled Receptors

1995 • 415 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

Unconventional Myosins

1995 • 362 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)

1996 • 309 citations

Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members

1996 • 275 citations

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1996 • 268 citations

Role of Type I Myosins in Receptor-Mediated Endocytosis in Yeast

1996 • 263 citations

Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton.

1996 • 229 citations

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis.

1995 • 198 citations

Membrane ruffling and signal transduction

1994 • 183 citations

TEDS rule: A molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head

1995 • 179 citations

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

1996 • 176 citations

Localization and specificity of the phospholipid and actin binding sites on the tail of Acanthamoeba myosin IC

1992 • 130 citations

Inhibition of contractile vacuole function in vivo by antibodies against myosin-I

1993 • 120 citations

Regulation of calmodulin-binding myosins

1995 • 113 citations

Genomic Sequence Information Should Be Released Immediately and Freely in the Public Domain

1996 • 111 citations

Myosin-I moves actin filaments on a phospholipid substrate: implications for membrane targeting.

1992 • 107 citations

Monomeric Acanthamoeba myosins I support movement in vitro.

1985 • 106 citations

Activation of Myosin-I by Members of the Ste20p Protein Kinase Family

1996 • 100 citations

Regulation of Class I and Class II Myosins by Heavy Chain Phosphorylation

1996 • 95 citations

Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly.

1996 • 92 citations

Cloning and Characterization of a Dictyostelium Myosin I Heavy Chain Kinase Activated by Cdc42 and Rac

1996 • 88 citations

The localization and sequence of the phosphorylation sites of Acanthamoeba myosins I

1989 • 85 citations

Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation

1995 • 80 citations

Molecular Cloning and Sequencing of the Cytostatic G Protein-activated Protein Kinase PAK I

1996 • 77 citations

The actin binding site in the tail domain of Dictyostelium myosin 1C (myoC) resides within the glycine‐ and proline‐rich sequence (tail homology region 2)

1994 • 69 citations

A myosin family reunion

1996 • 63 citations

Quantification and localization of phosphorylated myosin I isoforms in Acanthamoeba castellanii.

1995 • 59 citations

The Renaturable 69- and 63-kDa Protein Kinases That Undergo Rapid Activation in Chemoattractant-stimulated Guinea Pig Neutrophils Are p21-Activated Kinases

1996 • 59 citations

Purification and characterization of a third isoform of myosin I from Acanthamoeba castellanii

1989 • 57 citations

The Catalytic Domain of Acanthamoeba Myosin I Heavy Chain Kinase

1996 • 56 citations

Acanthamoeba myosin I heavy chain kinase is activated by phosphatidylserine-enhanced phosphorylation.

1990 • 53 citations

Activation of actin-activated ATPase in smooth muscle by phosphorylation of myosin light chain with protease-activated kinase I.

1984 • 48 citations

Substrate specificity of Acanthamoeba myosin I heavy chain kinase as determined with synthetic peptides.

1990 • 47 citations

Purification and Characterization of a Dictyostelium Protein Kinase Required for Actin Activation of the Mg2+ATPase Activity of Dictyostelium Myosin ID

1995 • 47 citations

Localization of the actin-binding sites of Acanthamoeba myosin IB and effect of limited proteolysis on its actin-activated Mg2+-ATPase activity.

1988 • 40 citations

[2] Purification of myosin I and myosin I heavy chain kinase from Acanthamoeba castellanii

1991 • 29 citations

The Catalytic Domain of Acanthamoeba Myosin I Heavy Chain Kinase

1996 • 24 citations

Phosphorylation and activation of smooth muscle myosin by Acanthamoeba myosin I heavy chain kinase.

1984 • 23 citations

Properties of Acanthamoeba Myosin I Heavy Chain Kinase Bound to Phospholipid Vesicles

1995 • 14 citations

Preparation of a phospholipid-insensitive, autophosphorylation-activated catalytic fragment of Acanthamoeba myosin I heavy chain kinase.

1992 • 12 citations

Autophosphorylation-independent activation of Acanthamoeba myosin I heavy chain kinase by plasma membranes.

1993 • 12 citations

Chapter 2 Acanthamoeba Myosin I: Past, Present, and Future

1991 • 9 citations