Mutagenic and carcinogenic N-nitroso compounds: Possible environmental hazards

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

1967 • 1,408 citations

Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten

1967 • 1,336 citations

Carcinogenic Nitroso Compounds

1967 • 1,109 citations

A MODEL FOR GASTRIC CANCER EPIDEMIOLOGY

1975 • 1,091 citations

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

1975 • 1,030 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

The Production of Malignant Primary Hepatic Tumours in the Rat by Feeding Dimethylnitrosamine

1956 • 877 citations

Formation of N-nitroso compounds: Chemistry, kinetics, and in vivo occurrence

1975 • 759 citations

Detection of chemical mutagens by the dominant lethal assay in the mouse

1972 • 572 citations

Ascorbate-Nitrite Reaction: Possible Means of Blocking the Formation of Carcinogenic N -Nitroso Compounds

1972 • 506 citations

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1970 • 500 citations

Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo

1962 • 399 citations

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1968 • 378 citations

Some Toxic Properties of Dimethylnitrosamine

1954 • 317 citations

In vitro and host-mediated “rec-assay” procedures for screening chemical mutagens; and phloxine, a mutagenic red dye detected

1972 • 301 citations

Some chemical aspects of dose-response relationships in alkylation mutagenesis

1974 • 284 citations

Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes☆

1971 • 267 citations

Carcinoma and Intestinal Metaplasia of the Stomach in Colombian Migrants<xref ref-type="fn" rid="FN2">2</xref>

1970 • 266 citations

The properties of in templates for RNA polymerase

1973 • 264 citations

Transplacentare Erzeugung maligner Tumoren des Nervensystems

1968 • 264 citations

Role of nutrition in the drug-metabolizing enzyme system.

1974 • 250 citations

Cell‐mediated mutagenesis of mammalian cells with chemical carcinogens

1974 • 243 citations

Oesophageal Cancer Studies in the Caspian Littoral of Iran: The Caspian Cancer Registry

1973 • 230 citations

Chemical Mutagens in the Human Environment

1968 • 224 citations

Rapid detection of mutagens and carcinogens.

1971 • 218 citations

Microsomal metabolism of dimethylnitrosamine and the cytochrome P-450 dependency of its activation to a mutagen.

1973 • 212 citations

A Host-Mediated Microbial Assay for the Detection of Mutagenic Compounds

1969 • 209 citations

The decomposition and toxicity of dialkylnitrosamines in rats

1962 • 200 citations

Scientific Foundations of Oncology

1976 • 196 citations

Human, rat and mouse liver‐mediated mutagenicity of vinyl chloride in S. typhimurium strains

1975 • 194 citations

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

1975 • 193 citations

Bacteria and the N-Nitrosation of Secondary Amines

1971 • 186 citations

<italic>Brief Communication:</italic> Carcinogenicity of N-Methyl-N-nitrosourea: Possible Role of Excision Repair of O<sup>6</sup>-Methylguanine From DNA

1974 • 182 citations

Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nervous system by ethylnitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues

1974 • 181 citations

Specific Carcinogenic and Teratogenic Effects of ‘Indirect’ Alkylating Methyl and Ethyl compounds, and their Dependency on Stages of Ontogenic Developments

1973 • 173 citations

Chemical Carcinogens as Frameshift Mutagens: Salmonella DNA Sequence Sensitive to Mutagenesis by Polycyclic Carcinogens

1974 • 169 citations

Induction of mitotic gene conversion by mutagens.

1971 • 165 citations

Mechanism of Alkylation of Nucleic Acids by Nitrosodimethylamine

1968 • 162 citations

Survival in Toxic Environments

1974 • 160 citations

Specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo

1975 • 159 citations

Toxic liver injury and carcinogenesis. Methylation of proteins of rat-liver slices by dimethylnitrosamine in vitro

1962 • 153 citations

Isolation and identification of a hepatotoxic factor in herring meal produced from sodium nitrite preserved herring

1964 • 149 citations

Estimation of Steam-Volatile N-Nitrosamines in Foods at the 1 µg/kg Level

1972 • 142 citations

Nitrosamine-induced carcinogenesis. The alkylation of N-7 of guanine of nucleic acids of the rat by diethylnitrosamine, N-ethyl-N-nitrosourea and ethyl methanesulphonate

1971 • 140 citations

The Cytoplasm of Hepatocytes during Carcinogenesis

1968 • 140 citations

The Enzymatic Release of O ⁶ -methylguanine and 3-methyladenine from DNA Reacted with the Carcinogen N -methyl- N -nitrosourea

1974 • 138 citations

N‐NITROSO COMPOUNDS IN ORGANOTROPIC AND TRANSPLACENTAL CARCINOGENESIS*

1969 • 136 citations

Induction of Liver Cell Adenomata in the Rat by a Single Treatment with N-Methyl-N-Nitrosourea given at Various Times after Partial Hepatectomy

1974 • 133 citations

Rapid induction of bladder cancer in rats with N-methyl-N-nitrosourea I. Histology

1972 • 126 citations

Induction of mitotic gene conversion with nitrous acid, 1-methyl-3-nitro-1-nitrosoguanidine and other alkylating agents in Saccharomyces cerevisiae

1967 • 123 citations

The rate of breakdown of methyl methanesulphonate, dimethyl sulphate and N-methyl-N-nitrosourea in the rat

1968 • 113 citations

In vitro metabolism and microsome-mediated mutagenicity of dialkylnitrosamines in rat, hamster, and mouse tissues.

1975 • 109 citations

Inactivation and mutation of coliphage T2 by N-methyl- and N-ethyl-N-nitrosourea

1969 • 109 citations

Dimethylnitrosamine; its Hepatotoxic Effect in Sheep and its Occurrence in Toxic Batches of Herring Meal

1965 • 104 citations

The origin of urinary dimethylamine

1965 • 103 citations

[Induction of neurogenic malignancies by one single dose of ethyl-nitrosourea (ENU) given to newborn and juvenile BD IX-strain rats].

1970 • 103 citations

Cellular injury and carcinogenesis. The effect of a protein-free high-carbohydrate diet on the metabolism of dimethylnitrosamine in the rat

1971 • 99 citations

Die Wirkung krebsausl�sender Nitrosamine und Nitrosamide auf das Adenin-6-45-R�ckmutationssystem vonSaccharomyces cerevisiae

1964 • 97 citations

Chromatographic methods for the study of amines from biological material

1961 • 97 citations

Nitrosopyrrolidine and Dimethylnitrosamine in Bacon

1973 • 97 citations

The Host-Mediated Assay, a Practical Procedure for Evaluating Potential Mutagenic Agents in Mammals

1971 • 97 citations

The Properties of 7-Methylguanine-containing Templates for Ribonucleic Acid Polymerase

1970 • 97 citations

Effect of Beta-Oxidized Nitrosamines on Syrian Hamsters. III. 2,2′-Dihydroxydi-n-propylnitrosamine2

1975 • 96 citations

Nitrosaminsynthese durch Bakterien

1968 • 96 citations

Toxicology of N-nitroso compounds

1975 • 96 citations

The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals

1973 • 95 citations

The induction of tumours in the rat by a single oral dose of N-nitrosomethylurea.

1969 • 95 citations

Zur Entstehung carcinogener Nitrosamine am Beispiel des Tabakrauchs

1962 • 94 citations

Gas chromatographic determination and mass spectrometric confirmation of N-nitrosodimethylamine in smoke-processed marine fish

1971 • 94 citations

Cellular analysis of renal neoplasia: induction of renal tumors in dietary-conditioned rats by dimethylnitrosamine, with a reappraisal of morphological characteristics.

1970 • 92 citations

Mutagenicity of two potent carcinogens, dimethylnitrosamine and diethylnitrosamine, in Neurospora crassa

1966 • 92 citations

Nitrosocarbaryl as a Potent Mutagen of Environmental Significance

1974 • 91 citations

Erzeugung neurogener Malignome durch einmalige Gabe von �thyl-nitrosoharnstoff (�NH) an neugeborene und junge BD IX-Ratten

1970 • 88 citations

Mitotic recombination induced inSaccharomyces cerevisiae with nitrous acid, diethylsulfate and carcinogenic, alkylating nitrosamides

1966 • 88 citations

CLINICAL MANIFESTATIONS AND STUDIES IN PARENCHYMATOUS HEPATITIS

1937 • 86 citations

Nitrates, nitrites, and methemoglobinemia

1970 • 85 citations

Advances in the Chemistry of AliphaticN-Nitrosamines

1971 • 84 citations

The catalysis of nitrosation by thiocyanate from saliva

1971 • 83 citations

Chemical carcinogenesis: mechanisms and approaches to its control.

1971 • 82 citations

Comparative investigations on the chemical induction of point mutations and dominant lethal mutations in mice

1972 • 80 citations

Formation of Nitrosamines in a Meat Curing Mixture

1973 • 80 citations

Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and chromosome aberrations in chinese hamster cells

1973 • 79 citations

Evaluation of short-term tests for carcinogenicity

1974 • 79 citations

Naturally occurring nitrate and nitrite in foods in relation to infant methaemoglobinaemia

1971 • 78 citations

NITROSO COMPOUNDS

1969 • 78 citations

Chemically Induced Delayed Germinal Mutation in Drosophila

1965 • 77 citations

Effect of a single treatment with the alkylating carcinogens dimethylnitrosamine, diethylnitrosamine and methyl methanesulphonate, on liver regenerating after partial hepatectomy

1975 • 76 citations

Metabolism of Dimethylnitrosamine by Human Liver Slices in Vitro

1970 • 76 citations

Induction of Squamous Carcinoma of the Lung and of the Stomach and Oesophagus by Diazomethane and N-Methyl-N-Nitroso-Urethane, Respectively

1962 • 75 citations

Chemical Studies on Tobacco Smoke. XXXIII. N'-Nitrosonornicotine in Tobacco: Analysis of Possible Contributing Factors and Biologic Implications2

1975 • 74 citations

Carcinogen in a Transkeian Bantu Food Additive

1969 • 74 citations

Carcinogenic response of the respiratory tract of Syrain golden hamsters to different doses of diethylnitrosamine.

1968 • 73 citations

Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea—Evidence for transfer of the intact methyl group

1973 • 72 citations

Factors affecting metabolism and mutagenicity of dimethylnitrosamine and diethylnitrosamine.

1975 • 69 citations

Mammalian blood-mediated mutagenicity tests using a multipurpose strain of Escherichia coli K-12

1973 • 66 citations

Mutagenicity of nitrosamides and nitrosamidines in micro-organisms and plants

1976 • 65 citations

Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.

1970 • 64 citations

[The effect of phenobarbital and halogenated hydrocarbons on nitrosamine carcinogenesis].

1969 • 64 citations

Cellular injury and carcinogenesis. Inhibition of metabolism of dimethylnitrosamine by aminoacetonitrile

1970 • 63 citations

New developments in mutagenicity screening techniques with yeast.

1973 • 60 citations

Die Beeinflussung der Nitrosamincarcinogenese durch Phenobarbital und Halogenkohlenwasserstoffe

1969 • 60 citations

CHEMICAL INDUCTION OF DOMINANT LETHALS IN FEMALE MICE

1969 • 60 citations

Genetics of somatic mammalian cells XII: Mutagenesis by carcinogenic nitroso compounds

1971 • 56 citations

Microbial Mutagenicity of Streptozotocin in Animal-mediated Assays

1969 • 55 citations

Increased Carcinogenic Action of Dimethylnitrosamine after Prior Administration of Carbon Tetrachloride

1973 • 55 citations

Induction of mitotic gene conversion in Saccharomyces cerevisiae by N-nitrosated pesticides

1974 • 54 citations

Bacterial Production of Di-Methyl Nitrosamine in Salted Fish

1973 • 54 citations

The effect of dietary protein deficiency on the ability of isolated hepatic microsomes to alter the mutagenicity of a primary and a secondary carcinogen.

1974 • 54 citations

Blastomogenic Effect of Dimethylnitrosamine on Pregnant Rats and their Offspring

1968 • 53 citations

Interaction of N-alkyl-N-nitrosourethanes with thiols

1965 • 53 citations

In vitro versus in vivo metabolic activation of mutagens.

1973 • 51 citations

Development of host-mediated mutagenicity tests

1974 • 50 citations

The evidence for the presence of dimethylnitrosamine in meat products

1972 • 50 citations

Dimethylnitrosamine in frankfurters

1972 • 50 citations

Effects of diet and microsomal enzyme induction on the toxicity of dimethyl nitrosamine.

1969 • 50 citations

The occurrence and determination of N-Nitroso compounds

1975 • 50 citations

Cellular injury and carcinogenesis. Evidence for the alkylation of rat liver nucleic acids in vivo by N-nitrosomorpholine

1974 • 49 citations

A comparison of the mutagenic action of the methyl and ethyl derivatives of nitrosamides and nitrosamidines on Escherichia coli

1974 • 49 citations

Effect of some radiomimetic agents on deoxyribonucleic acid synthesis in Escherichia coli and transformation in Bacillus subtilis

1965 • 48 citations

Dimethylnitrosamine in Chinese marine salt fish

1973 • 47 citations

Differential mutagenicity of the amine and amide derivatives of nitroso compounds in Drosophila melanogaster

1966 • 47 citations

Factors affecting dimethylnitrosamine formation from simple precursors by rat intestinal bacteria

1972 • 47 citations

Nitrosopyrrolidine in Cooked Bacon

1973 • 46 citations

Mutagenicity of nitrosamides and nitrosamidines in micro-organisms and plants

1976 • 45 citations

Carcinogenic properties of certain rubber additives

1968 • 45 citations

Failure to Induce Tumors in Swiss Mice After Concurrent Administration of Amino Acids and Sodium Nitrite<xref ref-type="fn" rid="FN2">2</xref>

1972 • 45 citations

Nitrosamide als mutagene Agentien

1963 • 44 citations

The occurrence of tumours in f₁, f₂ and f₃ descendants of bd rats exposed to n‐nitrosomethylurea during pregnancy

1975 • 44 citations

Nitrosamines in Cigarette Smoke Condensate

1973 • 44 citations

Repression of dimethylnitrosamine-demethylase by typical inducers of microsomal mixed-function oxidases

1975 • 44 citations

MUTAGENICITY OF ALKYLATING CARCINOGENS*

1969 • 43 citations

The in vivo Formation of N-Nitrosamines in the Rat Bladder and their Subsequent Absorption

1974 • 42 citations

Rat and mouse tissue-mediated mutagenicity of ring-substituted 3,3-dimethyl-1-phenyltriazenes in Salmonella typhimurium

1976 • 42 citations

Genetic aspects of carcinogenesis

1971 • 42 citations

Mutagenic properties of N‐acetyl‐2‐aminofluorene and its metabolites in relation to the molecular mechanisms of carcinogenesis

1972 • 41 citations

The reaction of nitrite with pesticides. II. Formation, chemical properties and carcinogenic activity of the N-nitroso derivative of N-methyl-1-naphthyl carbamate (carbaryl)

1975 • 41 citations

Nitrosamine carcinogenesis: the importance of the persistence in DNA of alkylated bases in the organotropism of tumour induction

1976 • 41 citations

Mutagen specificity in the induction of karyotic versus cytoplasmic respiratory deficient mutants in yeast by nitrous acid and alkylating nitrosamides

1968 • 41 citations

The detection of chemical mutagens using the L5178y-Asn-murine leukemia in vitro and in a host-mediated assay.

1974 • 40 citations

Struktur von Metaboliten carcinogener Dialkylnitrosamine im Rattenurin

1973 • 39 citations

A comparison of chemically induced reversion patterns of salmonella typhimurium and saccharomyces cerevisiae mutants, using in vitro plate tests

1972 • 39 citations

In vitro metabolic activation of chemical mutagens. I. Development of an in vitro mutagenicity assay liver microsomal enzymes for the activation of dimethylnitrosamine to a mutagen

1975 • 38 citations

The inhibition of dimethylnitrosamine carcinogenesis in rat liver by aminoacetonitrile

1971 • 38 citations

Specific excision of ethylated purines from DNA of Escherichia coli treated with N-ethyl-N-nitrosourea

1975 • 38 citations

Mutagene Wirkung von Dimethylnitrosamin bei Drosophila melanogaster

1962 • 38 citations

Protection against Dimethylnitrosamine Toxicity by Pregnenolone-16α-Carbonitrile

1972 • 36 citations

Verteilung von N-[14C] Methyl-N-nitroharnstoff in der Ratte nach systemischer Applikation

1971 • 36 citations

Metabolic activation of mutagens in mammals host-mediated assay utilizing the induction of mitotic gene conversion in saccharomyces cerevisiae

1973 • 36 citations

Chromosome Aberrations in Xeroderma Pigmentosum Cells Exposed to the Carcinogens, 4-Nitroquinoline-1-oxide and N-Methyl-N'-nitro-nitrosoguanidine

1973 • 35 citations

�ber die Wirkung von Nitrosaminen auf Mikroorganismen

1962 • 35 citations

Nicht-Mutagenit�t von Nitrosaminen bei Neurospora crassa

1963 • 35 citations

Rapid formation of carcinogenic N-nitrosamines by interaction of nitrite with fungicides derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the rat stomach

1974 • 34 citations

The activity of some nitroso compounds in the mouse dominant-lethal mutation assay

1973 • 34 citations

INDUCTION OF MITOTIC CROSSING OVER IN SACCHAROMYCES CEREVISIAE BY BREAKDOWN PRODUCTS OF DIMETHYLNITROSAMINE, DIETHYLNITROSAMINE, 1-NAPHTHYLAMINE AND 2-NAPHTHYLAMINE FORMED BY AN IN VITRO HYDROXYLATION SYSTEM

1973 • 33 citations

Alkylation of Nucleic Acids of Rat Liver and Lung by Deuterated <italic>N</italic>-Nitrosodiethylamine <italic>In Vivo</italic><xref ref-type="fn" rid="FN1">2</xref>

1971 • 33 citations

Carcinogenic Effect of di- n -Propylnitrosamine in Syrian Golden Hamsters 2

1973 • 33 citations

Mutagenicity of Primary and Secondary Carcinogens Altered by Normal and Induced Hepatic Microsomes

1973 • 33 citations

N-Dimethylnitrosamine in Tobacco Smoke Condensate

1972 • 33 citations

The mode of action of N-methyl-N′-nitro-N-nitrosoguanidine in mutagenesis

1972 • 32 citations

Metabolism of Dimethylnitrosamine to Mutagenic Intermediates by Kidney Microsomal Enzymes and Correlation With Reported Host Susceptibility to Kidney Tumors2

1975 • 32 citations

In vitro metabolic activation of chemical mutagens II. The relationships among mutagen formation, metabolism and carcinogenicity for dimethylnitrosamine and diethylnitrosamine in the livers, kidneys and lungs of BALB/cJ, C57BL/6J and RF/J mice

1975 • 32 citations

Induction of pancreatic neoplasms by 2, 2′-dioxopropyl-N-propylnitrosamine

1975 • 32 citations

Mutagenicity of dimethylnitrosamine and diethylnitrosamine for Saccharomyces in an in vitro hydroxylation system

1971 • 32 citations

Mutagenicity of N-nitrosopiperazines for Salmonella typhimurium in the host-mediated assay.

1972 • 32 citations

Mutagenicity of N-nitrosomorpholine in the host-mediated assay

1971 • 31 citations

Mutagenic activation or dimethylnitrosamine and diethylnitrosamine in the host-mediated assay and the microsomal system

1974 • 31 citations

Cytochrome P-450 Content and the Ability of Liver Microsomes From Patients Undergoing Abdominal Surgery to Alter the Mutagenicity of a Primary and a Secondary Carcinogen2

1973 • 30 citations

The mutational spectrum produced in Drosophila by N-methyl-N′-nitro-N-nitrosoguanidine

1969 • 30 citations

Mutation fixation in MNNG-treated haemophilus influenzae as determined by transformation

1974 • 30 citations

Regulatory gene mutations affecting arginine biosynthesis in Escherichia coli

1971 • 28 citations

Carcinogenic Effects of Di-<italic>n</italic>-propylnitrosamine, β-Hydroxypropyl-<italic>n</italic>-propylnitrosamine, and Methyl-<italic>n</italic>-propylnitrosamine on Sprague-Dawley Rats

1975 • 28 citations

Comparison of the genetic activity of dimethylnitrosamine, ethyl methanesulfonate, 2-acetylaminofluorene and ICR-170 in Saccharomyces cerevisiae strains D3, D4 and D5 using in vitro assays with and without metabolic activation

1974 • 28 citations

Effect of Beta-Oxidized Nitrosamines on Syrian Golden Hamsters. II. 2-Oxopropyl-n-propylnitrosamine2

1974 • 28 citations

Molecular Mechanisms of Chemical Carcinogenesis

1975 • 28 citations

Activation of nitrosomorpholine and nitrosopyrrolidine to bacterial mutagens

1974 • 27 citations

Mutagenic properties of benzo(a)pyrene and its methylated derivatives in relation to the molecular mechanisms of hydrocarbon carcinogenesis.

1973 • 27 citations

Mutagenic selectivity of carcinogenic nitroso compounds

1975 • 27 citations

Mutagenicity of dimethylnitrosamine in the metabolic process by rat liver microsomes☆

1973 • 26 citations

The mutagenic activity of N-nitroso-N-methylurethane and N-nitroso-N-ethylurethane in Schizosaccharomyces pombe

1966 • 26 citations

Differential effect of phenobarbitone, pregnenolone-16α-carbonitrile and aminoacetonitrile on dialkyinitrosamine metabolism and mutagenicity in vitro

1975 • 26 citations

The metabolism of N-methyl-N′-nitro-N-nitrosoguanidine in rats

1970 • 25 citations

Effect of polychlorinated biphenyls (Aroclor 1254) on inducible and repressible microsomal N-demethylases in the mouse and rat.

1975 • 25 citations

The lethal and mutagenic effects of N-nitroso-N-methyl-urethane and N-nitroso-N-ethylurethane in Colletotrichum coccodes

1964 • 25 citations

The effect of metabolic activation with rat liver preparations on the mutagenicity of several N-nitrosamines on a streptomycin-dependent strain of Escherichia coli

1974 • 25 citations

Metabolism of carcinogenic compounds. I. Effect of phenobarbital and methylcholanthrene on the activities of N-demethylation of carcinogenic compounds by liver microsomes of male and female rats.

1967 • 24 citations

Reaction kinetics of N-methyl-N'-nitro-N-nitrosoguanidine and N-ethyl-N'-nitro-N-nitrosoguanidine

1974 • 23 citations

Erzeugung von Tumoren im peripheren und zentralen Nervensystem durch Trimethyl-nitroso-harnstoff an Ratten

1965 • 23 citations

Microorganisms as test systems for mutagenicity

1971 • 23 citations

The influence of metabolism on mutagenic activity in the host-mediated assay

1971 • 20 citations

Mutagenic activity of N-methyl-N′-nitro-N-nitroso-guanidine NTG and N-methyl-N-nitrosourea (NMU) in Aspergillus nidulans

1974 • 20 citations

Involvement of DNA replication and repair in mutagenesis of Haemophilus influenzae induced by N-nitrosocarbaryl

1974 • 20 citations

N-nitrosocarbaryl-induced mutagenesis in Haemophilus influenzae strains deficient in repair and recombination

1975 • 19 citations

�ber das Spektrum einiger biochemischer Mutanten bei Escherichia coli nach Einwirkung von R�ntgenstrahlen und cancerogenen Substanzen

1964 • 19 citations

Cysteine protection against reversion to methionine independence induced by N-nitroso-N-methylurethane in Schizosaccharomyces pombe

1964 • 19 citations

Mutagenicity of primary amines combined with nitrate

1974 • 18 citations

Eine Ungew�hnliche Dosiswirkungs-Beziehung der N-Nitroso-N-Methylacetamid Induzierten Mutations-Raten beiSaccharomyces Cerevisiae

1963 • 18 citations

Cytogenetic studies in Sprague-Dawley rats during the administration of a carcinogenic nitroso compound—Diethylnitrosamine

1971 • 18 citations

An organ-specific host-mediated microbial assay for detecting chemical mutagens in vivo: Demonstration of mutagenic action in rat testes following streptozotocin treatment

1971 • 18 citations

Induction by N-methyl-N′-nitro-N-nitrosoguanidine and UV light of petite mutants in aerobically and anaerobically cultivated saccharomyces cerevisiae

1970 • 18 citations

Diethylnitrosamine-Induced Chromosome Changes in Rat Liver Cells2

1974 • 18 citations

Decreased toxicity of dimethylnitrosamine in rats after treatment with carbon tetrachloride

1973 • 18 citations

Die Wirkung von Methyl- und Äthylnitrosourethan, Diäthylsulfat und Methylmethansulfonat auf zwei Genorte von Neurospora sowie einen Mutationsort von Saccharomyces

1967 • 17 citations

Forward mutation studies with N-nitroso-N-methyl-urethane and N-nitroso-N-ethylurethane in Schizosaccharomyces pombe

1967 • 17 citations

Effect of N-nitroso-N-methylurea on viability and mutagenic response of repair-deficient strains of Escherichia coli

1974 • 17 citations

Some Effects of Chemical Carcinogens on Cell Organelles

1975 • 17 citations

�ber die mutagene Wirkung von R�ntgenstrahlen, N-nitroso-N-methyl-urethan und N-nitroso-morpholin bei Drosophila melanogaster

1964 • 17 citations

Reduction by pretreatment with dibenamine of hepatotoxicity induced by carbon tetrachloride, thioacetamide or dimethylnitrosamine

1974 • 16 citations

POSSIBILITIES OF HAZARD FROM NITROSAMINES IN INDUSTRY

1972 • 16 citations

Dietary modifications affecting the mutagenicity of N-nitroso compounds in the host-mediated assay.

1975 • 16 citations

Chemical constitution and mutagenic efficiency: Mutation induction inSaccharomyces cerevisiae by a homologous series of N-nitroso-N-methylcarbonamides

1966 • 16 citations

N-methyl-N′-nitro-N-nitrosoguanidine and hydroxylamine induced mutants of the rII region of phage T4

1974 • 15 citations

Zur Reaktion von Nitrit mit Pestiziden

1974 • 15 citations

Keine Mutationsausl�sung durch N-Nitrosopiperidin und N-N-Dinitrosopiperazin bei Escherichia coli

1965 • 15 citations

Toxicity of dimethylnitrosamine for the rat testis

1970 • 14 citations

Microsomal activation of dimethylnitrosamine to metabolites mutagenic in Neurospora crassa

1975 • 13 citations

Dimethylnitrosamine-induced inhibition of hepatic protein synthesis in vitro and the effect of pretreatment with cystamine or pregnenolone-16alpha-carbonitrile.

1975 • 13 citations

Screening of compounds structurally and functionally related to N-methyl-N'-nitro-N-nitrosoquanidine, a gastric carcinogen.

1974 • 13 citations

Chemical mutagenesis in E. coli B/R; the influence of repair systems for UV damage

1969 • 13 citations

Dibenamine: Selective protection against diethylnitrosamine-induced hepatic carcinogenesis but not oral, pharyngeal and esophageal carcinogenesis

1974 • 12 citations

Zur Reaktion von Nitrit mit Pestiziden: Bildung, chemische Eigenschaften und cancerogene Wirkung der N-Nitrosoverbindung des Herbizids N-methyl-N?-(2-benzothiazolyl-harnstoff (Benthiazuron)

1974 • 12 citations

Recent Topics In Chemical Carcinogenesis.

1976 • 11 citations

Mutagenic selectivity of carcinogenic nitroso compounds I. N-methyl-N-nitrosourethane

1975 • 11 citations

Analysis of a case of mutagen specificity in Neurospora crassa

1972 • 10 citations

Some Factors Affecting the Host-Mediated Assay Response

1973 • 10 citations

The evaluation of mutagenicity tests within the scope of toxicological trials

1971 • 10 citations

Action of supermutagens on the transforming DNA of Bacillus subtilis

1972 • 10 citations

A nitrosated arginine derivative, a powerful mutagen

1973 • 7 citations

Organic Analyses of Selected Areas of Surveyor III recovered on the Apollo 12 Mission

1971 • 5 citations

Die mutagene Wirkung von N-nitroso-N-methylacetamid bei Drosophila melanogaster

1967 • 5 citations

Mutation and recombination experiments with yeast as prescreening tests for carcinogenic effects?

1974 • 5 citations

Verteilung und Verweilzeit von Dimethylnitrosamin im Organismus der Ratte

1967 • 4 citations

Revertants of an Escherichia coli K-12 strain with high sensitivity to radiations and chemicals

1973 • 4 citations

Analysis of the storage effect of nitrosoethylurethane (NEU) in Neurospora crassa

1973 • 4 citations

Modern Trends in Toxicology - 2.

1975 • 4 citations

Zu Max Bodensteins sechzigstem Geburtstag

1931 • 2 citations

Die mutagene Wirkung von N-Nitroso-N-Methylacetamid beiEscherichia Coli

1967 • 2 citations