In vitro metabolism and microsome-mediated mutagenicity of dialkylnitrosamines in rat, hamster, and mouse tissues.

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

1967 • 1,408 citations

Carcinogenic Nitroso Compounds

1967 • 1,109 citations

The Detection of Chemical Mutagens with Enteric Bacteria

1971 • 414 citations

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1968 • 378 citations

Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes☆

1971 • 267 citations

Induction of kidney tumours in the rat with dimethylnitrosamine (N‐nitrosodimethylamine)

1962 • 209 citations

Differential effect of polycyclic hydrocarbons on the demethylation of the carcinogen dimethylnitrosamine by rat tissues

1968 • 96 citations

Induction of tumors in the Syrian hamster with diethylnitrosamine (N-nitrosodiethylamine).

1963 • 91 citations

Metabolism of Dimethylnitrosamine by Human Liver Slices in Vitro

1970 • 76 citations

Carcinogenic response of the respiratory tract of Syrain golden hamsters to different doses of diethylnitrosamine.

1968 • 73 citations

Induction of Liver Tumors in the Syrian Golden Hamster by Feeding Dimethylnitrosamine<xref ref-type="fn" rid="FN2">2</xref>

1964 • 55 citations

Effect of Route of Administration on the Carcinogenic Action of Diethylnitrosamine (N-Nitrosodiethylamine)

1964 • 54 citations

Mechanism of 3-methylcholanthrene-induced inhibition of dimethylnitrosamine demethylase in rat liver.

1970 • 54 citations

In vitro versus in vivo metabolic activation of mutagens.

1973 • 51 citations

Combined Carcinogenic Effects of Dimethyl-nitrosamine and 3-Methylcholanthrene in the Rat<xref ref-type="fn" rid="FN2">2</xref>

1968 • 49 citations

The Effects of Multiple and Single Administration of Dimethylnitrosamine to Hamsters

1967 • 44 citations

Selektive Erzeugung von Carcinomen der Nasenhöhle bei Ratten durch N,N′-Di-Nitrosopiperazin, Nitrosopiperidin, Nitrosomorpholin, Methyl-allyl-, Dimethyl- und Methyl-vinyl-nitrosamin

1964 • 41 citations

Protection against Dimethylnitrosamine Toxicity by Pregnenolone-16α-Carbonitrile

1972 • 36 citations

Effect of inducers of drug-metabolizing enzymes on diethylnitrosamine metabolism and toxicity

1971 • 32 citations

Carcinogenic Response of the Hamster Respiratory Tract to Single Subcutaneous Administrations of Diethyinitrosamine at Birth<xref ref-type="fn" rid="FN2">2</xref>

1970 • 27 citations

Die Minimaldosis f�r die Wirkung von Di�thylnitrosamin auf die Trachea beim Goldhamster

1966 • 26 citations

Histopathological and autoradiographic studies on kidney tumors induced by N-nitrosodimethylamine in rat.

1966 • 26 citations

The effect of metabolic activation with rat liver preparations on the mutagenicity of several N-nitrosamines on a streptomycin-dependent strain of Escherichia coli

1974 • 25 citations

Metabolism of carcinogenic compounds. I. Effect of phenobarbital and methylcholanthrene on the activities of N-demethylation of carcinogenic compounds by liver microsomes of male and female rats.

1967 • 24 citations

Metabolism of dimethylnitrosamine by amphibians and fish in vitro

1973 • 20 citations