Action of supermutagens on the transforming DNA of Bacillus subtilis

REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS

1961 • 2,206 citations

Optimal conditions for mutagenesis by N-methyl-N′-nitro-N-nitrosoguanidine in escherichia coli K12

1965 • 1,394 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1970 • 500 citations

Mutagenesis of the replication point by nitrosoguanidine: Map and pattern of replication of the Escherichia coli chromosome

1968 • 297 citations

A new chemical mutagen for bacteria, 1-methyl-3-nitro-1-nitrosoguanidine

1960 • 212 citations

Mutagenic and Inactivating DNA Alterations

1966 • 122 citations

Inactivation and mutation of coliphage T2 by N-methyl- and N-ethyl-N-nitrosourea

1969 • 109 citations

Diazomethane as the active agent in nitrosoguanidine mutagenesis and lethality

1968 • 107 citations

Denaturation of deoxyribonucleic acid by formamide

1961 • 88 citations

INDUCTION OF MUTATIONS IN TRANSFORMING DNA BY HYDROXYLAMINE

1962 • 81 citations

Genetic effects of N-methyl-N′-nitro-N-nitrosoguanidine in Neurospora crassa

1970 • 69 citations

Enzymes of the tryptophan operon of Bacillussubtilis

1969 • 66 citations

Messenger and template activities of chemically modified polynucleotides

1970 • 65 citations

The mutagenic activity of 1-alkyl-1-nitrosoureas and 1-alkyl-3-nitro-1-nitrosoguanidines

1967 • 57 citations

The mutagenic and lethal effects of monofunctional methylating agents in strains of Haemophilus influenzae defective in repair processes

1971 • 49 citations

Effect of some radiomimetic agents on deoxyribonucleic acid synthesis in Escherichia coli and transformation in Bacillus subtilis

1965 • 48 citations

Chemical modification of viral ribonucleic acid. VII. Action of methylating agents and nitrosoguanidine on polynucleotides including tobacco mosaic virus ribonucleic acid

1969 • 48 citations

Chemical modification of viral ribonucleic acid. VIII. Chemical and biological effects of methylating agents and nitrosoguanidine on tobacco mosaic virus

1969 • 46 citations

The influence of pH on the mutagenicity in yeast of N-methylnitrosamides and nitrous acid

1965 • 42 citations

Chemical modification of viral RNA. VI. The action of N-methyl-N'-nitro-N-nitrosoguanidine.

1967 • 41 citations

Inactivation and mutagenesis on isolated DNA. I. Theory of inactivation of transforming DNA

1967 • 34 citations

Inactivation and mutagenesis on isolated DNA II. Kinetics of mutagenesis and efficiency of different mutagens

1968 • 33 citations

Mutagenicity of alkyl and nitroso-alkyl compounds acting on tobacco mosaic virus and its RNA

1969 • 33 citations

Reaction of Nitrosoguanidine ( N -Methyl- N ′-Nitro- N -Nitrosoguanidine) with Tobacco Mosaic Virus and Its RNA

1968 • 32 citations

Transforming activity in single-stranded DNA from Bacillus subtilis

1968 • 29 citations

Study of the methylation and lack of deamination of deoxyribonucleic acid by N-methyl-N′-nitro-N-nitrosoguanidine

1969 • 26 citations

The mutagenic activity of N-nitroso-N-methylurethane and N-nitroso-N-ethylurethane in Schizosaccharomyces pombe

1966 • 26 citations

Mechanism of mutagenesis by N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG). Methylation of nucleic acids by N‐trideuteriomethyl‐N′‐nitro‐N‐nitrosoguanidine (D3‐MNNG) in the presence of cysteine and in cells of Escherichia coli

1971 • 18 citations

Forward mutation studies with N-nitroso-N-methyl-urethane and N-nitroso-N-ethylurethane in Schizosaccharomyces pombe

1967 • 17 citations

Chemical constitution and mutagenic efficiency: Mutation induction inSaccharomyces cerevisiae by a homologous series of N-nitroso-N-methylcarbonamides

1966 • 16 citations

Theoretical relationship between probability of marker integration and length of donor DNA in pneumococcal transformation

1968 • 14 citations

II. Produkte der Reaktion von 1-Nitroso-3-nitro-1-methyl-guanidin mit Nucleobasen, Nucleosiden, Nucleosidphosphaten und Homopolyribonucleinsäuren

1968 • 11 citations

Action of N-methyl-N′-nitro-N-nitrosoguanidine on transforming DNA of Bacillus subtilis

1970 • 6 citations