cDNA Cloning and Functional Analysis of the p97 Subunit of the 26S Proteasome, a Polypeptide Identical to the Type‐1 Tumor‐Necrosis‐Factor‐Receptor‐Associated Protein‐2/55.11

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Getting started with yeast

2002 • 3,496 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1994 • 2,480 citations

[1] Getting started with yeast

1991 • 2,456 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

1995 • 862 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

The SIT4 protein phosphatase functions in late G1 for progression into S phase.

1991 • 340 citations

A 200‐amino acid ATPase module in search of a basic function

1995 • 339 citations

Proteasomes: protein degradation machines of the cell

1994 • 320 citations

One-Step Gene Disruption in Yeast

1989 • 310 citations

Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor

1995 • 265 citations

Production and characterization of monoclonal antibodies specific to multi‐ubiquitin chains of polyubiquitinated proteins

1994 • 245 citations

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit

1993 • 244 citations

Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome.

1994 • 238 citations

A cDNA for a Protein That Interacts with the Human Immunodeficiency Virus Tat Transactivator

1990 • 234 citations

PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family.

1994 • 200 citations

Primary structures of two homologous subunits of PA28, a γ‐interferon‐inducible protein activator of the 20S proteasome

1995 • 196 citations

Calculation of the isoelectric points of polypeptides from the amino acid composition

1986 • 185 citations

cDNA Cloning and Interferon γ Down-Regulation of Proteasomal Aubunits X and Y

1994 • 181 citations

Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease.

1994 • 175 citations

KEKE motifs

1994 • 173 citations

Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family

1992 • 171 citations

New human gene encoding a positive modulator of HIV Tat-mediated transactivation

1992 • 163 citations

Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome.

1996 • 143 citations

Identification, Purification, and Characterization of a PA700-dependent Activator of the Proteasome

1996 • 138 citations

Subunits of the regulatory complex of the 26S protease

1995 • 127 citations

Proteasomes are essential for yeast proliferation. cDNA cloning and gene disruption of two major subunits.

1990 • 127 citations

Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae.

1995 • 94 citations

Molecular biology of proteasomes

1995 • 93 citations

Inhibition of Ubiquitin-mediated Proteolysis by the Arabidopsis 26 S Protease Subunit S5a

1995 • 90 citations

Construction of a human full-length cDNA bank

1994 • 82 citations

Molecular Structures of 20S and 26S Proteasomes

1993 • 79 citations

Rapid Degradation of AU-Rich Element (ARE) mRNAs Is Activated by Ribosome Transit and Blocked by Secondary Structure at Any Position 5′ to the ARE

1995 • 76 citations

The Yeast SEN3 Gene Encodes a Regulatory Subunit of the 26S Proteasome Complex Required for Ubiquitin-Dependent Protein Degradation In Vivo

1995 • 74 citations

Purification and characterization of an endogenous inhibitor specific to the Z‐Leu‐Leu‐Leu‐MCA degrading activity in proteasome and its identification as heat‐shock protein 90

1994 • 73 citations

Molecular cloning of cDNA for proteasomes from rat liver: primary structure of component C3 with a possible tyrosine phosphorylation site

1990 • 73 citations

Cloning and Sequencing a Non-ATPase Subunit of the Regulatory Complex of the Drosophila 26S Protease

1995 • 62 citations

A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its ‘death domain’

1995 • 61 citations

cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p

1995 • 60 citations

CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p.

1996 • 54 citations

Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila

1990 • 42 citations

cDNA Cloning of p40, a Regulatory Subunit of the Human 26S Proteasome, and a Homolog of the Mov-34 Gene Product

1995 • 28 citations

cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family

1996 • 27 citations

Cloning and Sequencing a Non-ATPase Subunit of the Regulatory Complex of the Drosophila 26S Protease

1995 • 11 citations