Retinoic acid receptor α1 isoform is induced by estradiol and confers retinoic acid sensitivity in human breast cancer cells

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Statistical methods

1967 • 19,533 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

The retinoids—Biology, chemistry and medicine

1996 • 1,192 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

The Retinoids-Biology, Chemistry and Medicine

1994 • 987 citations

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

1991 • 856 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit.

1987 • 320 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

1990 • 248 citations

Mitogenic stimulation of human breast cancer cells in a growth factor‐defined medium: Synergistic action of insulin and estrogen

1988 • 245 citations

Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues.

1994 • 218 citations

High frequency of retinoic acid receptor beta abnormalities in human lung cancer.

1991 • 216 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen.

1994 • 198 citations

Expression and regulation of retinoic acid receptors in human breast cancer cells.

1992 • 143 citations

Retinoic acid resistance of estradiol-independent breast cancer cells coincides with diminished retinoic acid receptor function

1993 • 126 citations

Implication of RARB in Epidermoid (Squamous) Lung Cancer

1991 • 83 citations

Estradiol induction of retinoic acid receptors in human breast cancer cells.

1993 • 81 citations

Retinoid-sensitive cells and cell lines

1990 • 80 citations

Antiestrogenic effects of all-trans-retinoic acid and 1,25-dihydroxyvitamin D3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms.

1994 • 80 citations

Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent

1987 • 76 citations

Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-α)

1990 • 70 citations

Estrogen receptor‐negative breast cancer cells transfected with the estrogen receptor exhibit increased RARα gene expression and sensitivity to growth inhibition by retinoic acid

1993 • 67 citations

The retinoids: Biology, chemistry and medicine (2nd edn)

1994 • 56 citations

Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines

1984 • 48 citations

Retinoic acid inhibition of human breast carcinoma proliferation is accompanied by inhibition of the synthesis of a Mr 39,000 protein.

1990 • 45 citations

Contemporary issues in clinical nutrition

1983 • 29 citations

Modulation of microfilament protein composition by transfected cytoskeletal actin genes.

1988 • 20 citations

EXPRESSION OF THE RETINOIC ACID NUCLEAR RECEPTORS (RARS) AND RETINOID X-RECEPTOR (RXR) GENES IN ESTROGEN-RECEPTOR POSITIVE AND NEGATIVE BREAST-CANCER

1994 • 11 citations