Lerk2 (Ephrin-B1) Is a Collapsing Factor for a Subset of Cortical Growth Cones and Acts by a Mechanism Different from AL-1 (Ephrin-A5)

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Effects of cytochalasin and phalloidin on actin.

1987 • 1,989 citations

Taxol stabilizes microtubules in mouse fibroblast cells.

1980 • 1,942 citations

Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.

1988 • 851 citations

Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 • 851 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Ligands for EPH-Related Receptor Tyrosine Kinases that Require Membrane Attachment or Clustering for Activity

1994 • 720 citations

Designing CD4 immunoadhesins for AIDS therapy

1989 • 612 citations

Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

1996 • 536 citations

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

1996 • 526 citations

Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo

1996 • 418 citations

Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors

1997 • 394 citations

Growth cone advance is inversely proportional to retrograde F-actin flow

1995 • 371 citations

The role of microtubule dynamics in growth cone motility and axonal growth.

1995 • 362 citations

Microtubule behavior in the growth cones of living neurons during axon elongation.

1991 • 343 citations

Making the connection: Cytoskeletal rearrangements during growth cone guidance

1995 • 343 citations

Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.

1996 • 334 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1994 • 332 citations

Effects of cytochalasin, phalloidin and pH on the elongation of actin filaments

1991 • 329 citations

Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain

1995 • 315 citations

Collapse of growth cone structure on contact with specific neurites in culture

1987 • 284 citations

The enrichment of a neuronal growth cone collapsing activity from embryonic chick brain

1990 • 279 citations

Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

1986 • 275 citations

The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor.

1993 • 262 citations

Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation

1995 • 261 citations

Cytoskeletal remodeling during growth cone-target interactions.

1993 • 250 citations

Localized collapsing cues can steer growth cones without inducing their full collapse

1995 • 241 citations

B61 is a ligand for the ECK receptor protein-tyrosine kinase

1994 • 239 citations

Axonal guidance in the chick visual system: Posterior tectal membanes induce collapse of growth cones from the temporal retina

1990 • 208 citations

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis.

1994 • 174 citations

ELF-2, a New Member of the Eph Ligand Family, Is Segmentally Expressed in Mouse Embryos in the Region of the Hindbrain and Newly Forming Somites

1995 • 155 citations

Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.

1994 • 141 citations

Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases.

1995 • 141 citations

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain

1994 • 135 citations

The role of microtubules in growth cone turning at substrate boundaries.

1995 • 127 citations

Eph receptor tyrosine kinases and their ligands in neural development

1996 • 125 citations

Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments.

1996 • 115 citations

Function of the Eph-related kinase rtk1 in patterning of the zebrafish forebrain

1996 • 113 citations

eph, the largest known family of putative growth factor receptors

1994 • 112 citations

Development of excitotoxicity in cultured hippocampal neurons

1989 • 105 citations

AL‐1‐induced Growth Cone Collapse of Rat Cortical Neurons is Correlated with REK7 Expression and Rearrangement of the Actin Cytoskeleton

1997 • 103 citations

Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk.

1995 • 101 citations

Axon guidance: A compelling case for repelling growth cones

1995 • 95 citations

The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.

1994 • 78 citations

Telling Axons Where to Grow: A Role for Eph Receptor Tyrosine Kinases in Guidance

1995 • 76 citations

Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily.

1994 • 74 citations

Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins.

1995 • 68 citations

Similarities and Differences in the Way Transmembrane-Type Ligands Interact with the Elk Subclass of Eph Receptors

1996 • 68 citations

In vitro experiments on axonal guidance and growth-cone collapse

1990 • 44 citations

Microtubules and the Mechanism of Directed Organelle Movement

1986 • 22 citations