Comparative Vibrational Spectroscopy of Intracellular Tau and Extracellular Collagen I Reveals Parallels of Gelation and Fibrillar Structure

Neuropathological stageing of Alzheimer-related changes

1991 • 14,533 citations

Sol-Gel Science

1990 • 3,199 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Circular Dichroism and the Conformational Analysis of Biomolecules

1996 • 1,897 citations

Molecular Size Distribution in Three Dimensional Polymers. I. Gelation¹

1941 • 1,795 citations

New insight into protein secondary structure from resolution-enhanced infrared spectra

1988 • 1,248 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

1989 • 989 citations

Tau in Alzheimer's disease

1998 • 936 citations

Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( ³⁰⁶ VQIVYK ³¹¹ ) forming β structure

2000 • 923 citations

Responsive Hydrogels from the Intramolecular Folding and Self-Assembly of a Designed Peptide

2002 • 882 citations

Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

1977 • 834 citations

Staging of Alzheimer-Related Cortical Destruction

1993 • 810 citations

Evolution of the neuropathology of Alzheimer's disease

1996 • 673 citations

Structural characterization of the core of the paired helical filament of Alzheimer disease.

1988 • 566 citations

RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments

1996 • 502 citations

Polyproline II structure in a sequence of seven alanine residues

2002 • 472 citations

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.

1992 • 463 citations

The Biosynthesis of Collagen

1974 • 434 citations

Spectroscopy of biological systems

1987 • 411 citations

Polymerization of τ into Filaments in the Presence of Heparin: The Minimal Sequence Required for τ ‐ τ Interaction

1996 • 387 citations

Protein Gels

1948 • 370 citations

The physical properties of cytoplasm

1950 • 360 citations

A nucleated assembly mechanism of Alzheimer paired helical filaments

1998 • 327 citations

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.

1995 • 317 citations

Infrared spectra and resonance interaction of amide‐I vibration of the antiparallel‐chain pleated sheet

1976 • 311 citations

New chain conformations of poly(glutamic acid) and polylysine

1968 • 306 citations

UV Resonance Raman-Selective Amide Vibrational Enhancement: Quantitative Methodology for Determining Protein Secondary Structure

1998 • 290 citations

Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.

1988 • 288 citations

Direct evidence that growth cones pull

1989 • 287 citations

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

1992 • 274 citations

The cytomechanics of axonal elongation and retraction.

1989 • 262 citations

Transmembrane molecular assemblies in cell-extracellular matrix interactions

1991 • 244 citations

Poly(Pro)II Helixes in Globular Proteins: Identification and Circular Dichroic Analysis

1994 • 239 citations

Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix

1995 • 234 citations

UV Resonance Raman excitation profiles of the aromatic amino acids

1986 • 230 citations

Wavelength dependence of the preresonance Raman cross sections of CH3CN, SO42−, ClO4−, and NO3−

1985 • 228 citations

Spectroscopy of biological systems

1986 • 225 citations

Structural bases of collagen stabilization induced by proline hydroxylation

2001 • 201 citations

Image reconstruction of the Alzheimer paired helical filament.

1985 • 184 citations

Dihedral ψ Angle Dependence of the Amide III Vibration: A Uniquely Sensitive UV Resonance Raman Secondary Structural Probe

2001 • 183 citations

Spontaneous Fiber Formation and Hydrogelation of Nucleotide Bolaamphiphiles

2002 • 171 citations

The cytomatrix: a short history of its study.

1984 • 169 citations

Assembly of Collagen Matrices as a Phase Transition Revealed by Structural and Rheologic Studies

2003 • 137 citations

Deep-ultraviolet Raman excitation profiles and vibronic scattering mechanisms of phenylalanine, tyrosine, and tryptophan

1989 • 136 citations

Combinatorial Library of Low Molecular‐Weight Organo‐ and Hydrogelators Based on Glycosylated Amino Acid Derivatives by Solid‐Phase Synthesis

2003 • 132 citations

MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth

1996 • 126 citations

Circular dichroism of collagen, gelatin, and poly(proline) II in the vacuum ultraviolet

1976 • 116 citations

UVRR spectroscopy of the peptide bond. 2. Carbonyl H-bond effects on the ground- and excited-state structures of N-methylacetamide

1991 • 115 citations

Tyrosine hydrogen-bonding and environmental effects in proteins probed by ultraviolet resonance Raman spectroscopy

1988 • 110 citations

The infrared spectrum and water binding of collagen as a function of relative humidity

1971 • 109 citations

α-Helix Structure in Alzheimer's Disease Aggregates of Tau-Protein

2002 • 108 citations

Stereochemistry of collagen*

1988 • 108 citations

Stereochemistry of collagen.

1988 • 103 citations

Strategy and Tactics in the Raman Spectroscopy of Biomolecules

1977 • 96 citations

The collagens; biochemistry and pathophysiology

1993 • 81 citations

Microheterogeneity Controls the Rate of Gelation of Actin Filament Networks

2002 • 76 citations

Hierarchical Phosphorylation of Recombinant Tau by the Paired‐Helical Filament‐Associated Protein Kinase Is Dependent on Cyclic AMP‐Dependent Protein Kinase

1999 • 71 citations

Vibrational spectra and normal coordinate analysis of p-cresol and its deuterated analogs

1988 • 70 citations

Ultraviolet resonance Raman study on the binding mode of enkephalin to phospholipid membranes

1992 • 69 citations

Secondary Structural Studies of Bovine Caseins: Structure and Temperature Dependence of β-Casein Phosphopeptide (1-25) as Analyzed by Circular Dichroism, FTIR Spectroscopy, and Analytical Ultracentrifugation

2002 • 68 citations

Ultraviolet resonance Raman spectroscopy of X—Proline bonds: A new marker band of hydrogen bonding at the imide CO site

1990 • 67 citations

A protein kinase associated with paired helical filaments in Alzheimer disease.

1992 • 65 citations

Amyloid, prions, and other protein aggregates

1999 • 62 citations

Biomolecular spectroscopy

1994 • 61 citations

Extracellular matrix allows PC12 neurite elongation in the absence of microtubules.

1990 • 60 citations

Rapid Loop Dynamics of Yersinia Protein Tyrosine Phosphatases

1997 • 58 citations

Saturation effects on ultraviolet resonance Raman intensities: Excimer/YAG laser comparison and aromatic amino acid cross‐sections

1990 • 57 citations

Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover.

1994 • 54 citations

Cytoskeletal mechanisms of neuronal degeneration

2001 • 52 citations

Interference reflection microscopic study of dorsal root growth cones on different substrates: Assessment of growth cone–substrate contacts

1988 • 51 citations

The Conformations of Filamentous and Soluble Tau Associated with Alzheimer Paired Helical Filaments

2002 • 39 citations

Amide III Mode φ, ψ Dependence in Peptides: A Vibrational Frequency Map

2001 • 38 citations

Structure Changes in Hemoglobin upon Deletion of C-Terminal Residues, Monitored by Resonance Raman Spectroscopy

1998 • 32 citations

In-plane force constants of the peptide group: Least-squares adjustment starting from ab initio values of N-methylacetamide

1984 • 31 citations

UV Resonance Raman Study of β93-Modified Hemoglobin A: Chemical Modifier-Specific Effects and Added Influences of Attached Poly(ethylene glycol) Chains

2001 • 25 citations

Microtubule dynamics in serum-starved and serum-stimulated swiss 3T3 mouse fibroblasts: Implications for the relationship between serum-induced contractility and microtubules

1998 • 23 citations

Aqueous Gel Formation of a Synthetic Peptide Derived from the β-Sheet Domain of Platelet Factor-4

2002 • 18 citations

The regulation of nerve fiber length by intercalated elongation and retraction

1985 • 17 citations

Oxidized and phosphorylated synthetic peptides corresponding to the second and third tubulin‐binding repeats of the τ protein reveal structural features of paired helical filament assembly

1997 • 17 citations

Raman Spectroscopic Characterization of Association and Thermoreversible Gelation in Aqueous Systems of Poly(N-acetamidoacrylamide)

1999 • 16 citations

UV resonance Raman study of angiotensin II conformation in nonaqueous environments: Lipid micelles and acetonitrile

2000 • 15 citations

Conformational differences in CO derivatives of HbA, HbC (Eβ6K) and HbS (Eβ6V) in the presence and absence of inositol hexaphosphate detected using ultraviolet resonance Raman spectroscopy

1998 • 14 citations

Regulatory roles of microtubule-associated proteins in neuronal morphogenesis. Involvement of the extracellular matrix

1999 • 14 citations

Conformational Changes in FmetHbS Probed with UV Resonance Raman and Fluorescence Spectroscopic Methods

1998 • 12 citations