Microtubule dynamics in serum-starved and serum-stimulated swiss 3T3 mouse fibroblasts: Implications for the relationship between serum-induced contractility and microtubules

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Dynamic instability of microtubule growth

1984 • 3,187 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING

1996 • 1,900 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion

1980 • 1,333 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro.

1997 • 451 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

Cellular Tensegrity: Exploring How Mechanical Changes in the Cytoskeleton Regulate Cell Growth, Migration, and Tissue Pattern during Morphogenesis

1994 • 428 citations

p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

1989 • 376 citations

Real-time observations of microtubule dynamic instability in living cells.

1988 • 364 citations

The role of microtubule dynamics in growth cone motility and axonal growth.

1995 • 362 citations

Involvement of microtubules in the control of adhesion-dependent signal transduction

1996 • 358 citations

Association of mitogen-activated protein kinase with the microtubule cytoskeleton.

1995 • 354 citations

Direct observation of microtubule dynamics in living cells

1988 • 318 citations

Signal transduction and actin filament organization

1996 • 309 citations

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle.

1995 • 305 citations

Fibroblast contractility and actin organization are stimulated by microtubule inhibitors

1989 • 303 citations

Selective stabilization of microtubules oriented toward the direction of cell migration.

1988 • 296 citations

Effect of colcemid on the locomotory behaviour of fibroblasts

1970 • 296 citations

Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.

1988 • 288 citations

Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.

1995 • 279 citations

Rho: a connection between membrane receptor signalling and the cytoskeleton

1996 • 271 citations

Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. Signaling pathways and cross-talk with platelet-derived growth factor.

1994 • 264 citations

Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain.

1995 • 229 citations

Microtubule Dynamics: Mechanism, Regulation, and Function

1991 • 228 citations

Tension and compression in the cytoskeleton of PC 12 neurites.

1985 • 224 citations

Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: Implications for the role of dynamic microtubules in cell locomotion

1995 • 218 citations

Microtubule Disruption Induces the Formation of Actin Stress Fibers and Focal Adhesions in Cultured Cells: Possible Involvement of the Rho Signal Cascade.

1996 • 214 citations

Evidence that microtubule depolymerization early in the cell cycle is sufficient to initiate DNA synthesis

1981 • 202 citations

Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific.

1993 • 197 citations

New features of microtubule behaviour observed in vivo

1988 • 191 citations

Phosphorylation of Microtubule-associated Proteins MAP2 and MAP4 by the Protein Kinase p110mark

1996 • 188 citations

Contact formation during fibroblast locomotion: involvement of membrane ruffles and microtubules.

1988 • 171 citations

Vinblastine suppresses dynamics of individual microtubules in living interphase cells.

1995 • 161 citations

Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin

1996 • 152 citations

Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation

1994 • 147 citations

Cytoskeleton

1988 • 129 citations

Okadaic acid induces interphase to mitotic-like microtubule dynamic instability by inactivating rescue.

1992 • 118 citations

Dynamics of microtubule depolymerization in monocytes.

1986 • 109 citations

Antitubulin agents enhance the stimulation of DNA synthesis by polypeptide growth factors in 3T3 mouse fibroblasts.

1979 • 108 citations

Cytochalasin separates microtubule disassembly from loss of asymmetric morphology.

1981 • 105 citations

Microtubules are stabilized in confluent epithelial cells but not in fibroblasts.

1990 • 103 citations

Modulation of microtubule dynamic instability in vivo by brain microtubule associated proteins

1995 • 99 citations

Microtubule-associated protein 2 alters the dynamic properties of microtubule assembly and disassembly

1993 • 91 citations

A thermodynamic model for force integration and microtubule assembly during axonal elongation

1988 • 80 citations

Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations

1990 • 78 citations

Stable expression of heterologous microtubule-associated proteins (MAPs) in Chinese hamster ovary cells: evidence for differing roles of MAPs in microtubule organization.

1994 • 75 citations

Induction of stable microtubules in 3T3 fibroblasts by TGF-β and serum

1994 • 75 citations

Kinetics of G1 transit following brief starvation for serum factors

1984 • 74 citations

Opposing microtubule- and actin-dependent forces in the development and maintenance of structural polarity in retinal photoreceptors

1989 • 65 citations

Initiation of DNA Synthesis in Cell Cultures by Colcemid

1971 • 55 citations

Myosin II phosphorylation and the dynamics of stress fibers in serum-deprived and stimulated fibroblasts.

1992 • 52 citations

Interphase microtubule dynamics are cell type-specific

1990 • 51 citations

Effect upon mitogenic stimulation of calcium-dependent phosphorylation of cytoskeleton-associated 350,000- and 80,000-mol-wt polypeptides in quiescent 3Y1 cells.

1985 • 51 citations

Distribution of detyrosinated microtubules in motile NRK fibroblasts is rapidly altered upon cell‐cell contact: Implications for contact inhibition of locomotion

1992 • 43 citations

Activation of microtubule-associated protein kinase by microtubule disruption in quiescent rat 3Y1 cells

1991 • 40 citations

Special type of morphological reorganization induced by phorbol ester: reversible partition of cell into motile and stable domains.

1987 • 37 citations

Rapid phosphorylation of microtubule-associated proteins through distinct mitogenic pathways.

1988 • 34 citations

Microtubules can modulate pseudopod activity from a distance inside macrophages

1996 • 33 citations

Influence of adhesion and cytoskeletal integrity on fibroblast traction

1996 • 31 citations

Depletion of lysophosphatidic acid triggers a loss of oriented detyrosinated microtubules in motile fibroblasts

1996 • 30 citations

Stimulation of microtubule dynamic turnover in living cells treated with okadaic acid

1996 • 25 citations

Microtubule-dependent effect of phorbol ester on the contractility of cytoskeleton of cultured fibroblasts.

1988 • 24 citations

Microtubule dynamic turnover is suppressed during polarization and stimulated in hepatocyte growth factor scattered Madin-Darby canine kidney epithelial cells

1996 • 20 citations

Disruption of microtubules induces formation of actin fibrils in density‐inhibited 3T3 cells.

1993 • 16 citations

Thursday, November 19, 1992: Symposia

1992 • 3 citations