A Novel cis -Regulatory Element, the PTS, Mediates an Anti-Insulator Activity in the Drosophila Embryo

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators

1999 • 1,076 citations

The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome

1989 • 939 citations

A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1993 • 858 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer

1985 • 531 citations

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

1992 • 418 citations

MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.

1995 • 391 citations

A group of scs elements function as domain boundaries in an enhancer-blocking assay.

1992 • 383 citations

Characterization of the chicken β-globin insulator

1997 • 381 citations

Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.

1993 • 358 citations

Polycombing the Genome: PcG, trxG, and Chromatin Silencing

1998 • 352 citations

THE BITHORAX COMPLEX

1987 • 326 citations

The abdominal region of the bithorax complex

1985 • 326 citations

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo.

1992 • 324 citations

POLYCOMBLIKE: A GENE THAT APPEARS TO BE REQUIRED FOR THE NORMAL EXPRESSION OF THE BITHORAX AND ANTENNAPEDIA GENE COMPLEXES OF DROSOPHILA MELANOGASTER

1982 • 258 citations

The 87A7 chromomere

1985 • 249 citations

abdA expression in Drosophila embryos.

1990 • 241 citations

Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex.

1996 • 237 citations

Modulation of enhancerá¤-promoter interactions by insulators in the Drosophilaembryo

1995 • 226 citations

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

1990 • 225 citations

Stopped at the border: boundaries and insulators

1999 • 222 citations

Different core promoters possess distinct regulatory activities in the Drosophila embryo

1998 • 219 citations

In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element

1990 • 202 citations

A Polycomb and GAGA Dependent Silencer Adjoins the Fab-7 Boundary in the Drosophila Bithorax Complex

1997 • 202 citations

The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.

1990 • 197 citations

The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain

2000 • 190 citations

Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster.

1991 • 180 citations

McpandFab-7: molecular analysis of putative boundaries of cis-regulatory domains in the bithorax complex ofDrosophila melanogaster

1994 • 166 citations

The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo.

1996 • 166 citations

The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex.

1993 • 154 citations

Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression

1997 • 137 citations

Silencers in abdominal-B, a homeotic Drosophila gene.

1993 • 130 citations

Chromatin domain boundaries in the Bithorax complex

1998 • 130 citations

Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated.

1990 • 118 citations

Characterization of the transvection mediating region of the Abdominal-B locus in Drosophila

1999 • 116 citations

Promoter specificity mediates the independent regulation of neighboring genes.

1996 • 115 citations

A silencer is required for maintenance of transcriptional repression throughoutDrosophiladevelopment

1997 • 106 citations

Compatibility between enhancers and promoters determines the transcriptional specificity of gooseberry and gooseberry neuro in the Drosophila embryo.

1994 • 105 citations

Dividing the empire: boundary chromatin elements delimit the territory of enhancers

1999 • 103 citations

Transvection in the iab-5,6,7 region of the bithorax complex of Drosophila: homology independent interactions in trans.

1995 • 102 citations

Control of the expression of the bithorax complex genes abdominal-A and Abdominal-B by c/s-regulatory regions in Drosophila embryos

1991 • 101 citations

Molecular definition of the morphogenetic and regulatory functions and the cis-regulatory elements of the Drosophila Abd-B homeotic gene

1991 • 96 citations

Transvection in the Drosophila Abd-B Domain: Extensive Upstream Sequences Are Involved in Anchoring Distant cis-Regulatory Regions to the Promoter

1998 • 88 citations

Distance-independent inactivation of an enhancer by the suppressor of Hairy-wing DNA-binding protein of Drosophila.

1993 • 87 citations

Polycomb Group Repression Is Blocked by the Drosophila suppressor of Hairy-wing [su(Hw)] Insulator

1998 • 77 citations

Two distinct mechanisms for differential positioning of gene expression borders involving the Drosophila gap protein giant

1998 • 68 citations

The molecular biology of olfactory perception.

1996 • 62 citations

Cis and trans interactions between the iab regulatory regions and abdominal-A and abdominal-B in Drosophila melanogaster.

1995 • 61 citations

Enhancer traps in the Drosophila bithorax complex mark parasegmental domains.

1994 • 57 citations

Functional specificity of the homeodomain protein fushi tarazu: the role of DNA-binding specificity in vivo.

1993 • 54 citations

Genetic and Molecular Analysis of Chromatin Domains

1993 • 49 citations

Chromatin boundaries: Punctuating the genome

1998 • 43 citations

Heritable Chromatin States Induced by the Polycomb and Trithorax Group Genes

2007 • 37 citations